The ACSL5 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ACSL5, and FACL5. This antibody recognizes Human, Mouse, and Rat antigen. The ACSL5 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Acyl-CoA synthetase 5, a member of the ACSL gene family that catalyzes the activation of long-chain fatty acids for lipid biosynthesis, is the only ACSL isoform that is both, located on mitochondria and functionally involved in enterocyte apoptosis.ACSL5 could play a role in promoting fatty acid-induced lipoapoptosis in hepatocytes as important mechanism in fatty liver-related disorders(PMID:20470896). ACSL5 is most abundant in liver, brown adipose tissue, and intestine and is located on both the mitochondrial membrane and endoplasmic reticulum(PMID:20798351). It has 3 isoforms produced by alternative splicing. This antibody is specific to ACSL5