The Mouse Anti Human Neuroblastoma RAS Viral Oncogene Homolog Antibody from MyBioSource.com is a Mouse Monoclonal antibody. The Mouse Anti Human Neuroblastoma RAS Viral Oncogene Homolog Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Introduction: NRAS binds GDP/GTP and has intrinsic GTPase activity. NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This transport is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. NRAS is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this NRAS gene result in juvenile myelomonocytic leukemia