The AR Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AKR1B1, Akr1b3, Akr1b7, aldose reductase, Amphiregulin, Androgen Receptor, AR, AREG, AREGB, DHTR, HUMARA, and TFM. This antibody recognizes Human, Mouse, and Rat antigen. The AR Polyclonal Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3)