The USH1C Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AIE-75, Harmonin, and Ush1c. This antibody recognizes Human, Mouse, and Rat antigen. The USH1C Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene