The GUCY2D Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GUCY2D. This antibody recognizes Human, Mouse, and Rat antigen. The GUCY2D Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases