The NFIA Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NFIA, and nuclear factor I A. This antibody recognizes Human, Mouse, and Rat antigen. The NFIA Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The NFI (nuclear factor I) family consists of four members in vertebrates (NFI-A, NFI-B, NFI-C and NFI-X), and the four NFI genes are expressed in unique patterns during mouse embryogenesis and in the adult. Four isoforms of NFIA were found in human and they play various roles in DNA replication, DNA-dependent transcritpion via their DNA binding property. Multiple residues of NFIA can be phosphorylated resulting in mild shifts of its practical molecular weight. Recent finding also revealed its neuroprotective function in NMDA-induced neuronal damage. It is a rabbit polyclonal antibody raised against N-terminal of human original NFIA