Histone H4 (D2X4V) Rabbit mAb 13919S from Cell Signaling Technology

Product Specs
ItemHistone H4 (D2X4V) Rabbit mAb
CompanyCell Signaling Technology
Price $357.00 Inquire
Catalog Number13919S
Quantity100 µl
ApplicationsW, IHC-P, IF-IC
ReactivityH, M, R, Mk, Dm, Z
TargetH4
HostRabbit
NCBI Full Gene NameH4 clustered histone 1
NCBI Gene AliasesH4-16, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, HIST1H4A
ClonalityMonoclonal
Research AreaChromatin Regulation / Nuclear Function
CloneD2X4V
Molecular Weight11

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stabilityMolecular CellFebruary 19, 2026Carlos Origel Marmolejo, Celina Sanchez, Erin Helms, Melissa J. McEvoy, Juyoung Lee, Marcel Werner, Paige Roberts, Stephan Hamperl, Joshua C. Saldivar,Cell Signaling Technology,Cat#4499S; RRID:AB_10544537 Rabbit monoclonal anti-histone H4 (D2X4V),Cell Signaling Technology,Cat#13919S; RRID:AB_2798345 Mouse monoclonal anti-Human 53BP1,BD Biosciences,Cat# 612522; RRID:AB_2206766 Rabbit

(2) Fork Reversal Safeguards Epigenetic Inheritance During Replication StressResearch SquareJanuary 29, 2026Wenpeng Liu, Caixian Zhou, Caixian Zhou, Nadia I. Martin, Nadia Martin, Tae-Hee Gwit, Tae-Hee Hedglin, Roséa Hedglin, Roséa Chen, Tianpeng Zhang, et al.dilution), H3K9ac (Millipore 07-352) (1:100 dilution), H3K9me3 (CST 13969) (1:100 dilution), H4 (CST 13919) (1:100 dilution); mouse biotin (Millipore B7653) (1:200 dilution) and mouse H2B (Abcam ab52484) (1:100

(3) Suppressing the OTUD7A/KDM5B/GABPA axis enhances the sensitivity of cisplatin through inducing ferroptosis in KRAS-mutant LUADCell Death & DiseaseDecember 20, 2025Rujia Si, Ziyang Shen, Ying Sui, Yue Shi, Yihan Zhang, Bowen Hu, Xin Chen, Bing Feng, Miao Lin Zhu, Xiaofeng Sha, et al.Epizyme, Shanghai, China. Anti-SLC7A11, anti-FTH-1, anti-NRF2 (29650), anti-H3 (4499), and anti-H4 (13919) antibodies were acquired from Cell Signaling Technology, USA. Anti-GABPA (PA5-88319) and anti-OTUD7A

(4) Overexpression of ATase1 and ATase2 disrupts the secretome and causes a progeria phenotypeLife science allianceDecember 1, 2025Cheng TL, Wu F, Haque ME, Thiel AR, Wang D, Helgager JJ, Li L, Puglielli L.Histone H2B (#12364, 1:1,000; Cell Signaling), Histone H3 (#4499, 1:1,000; Cell Signaling), Histone H4 (#13919, 1:1,000; Cell Signaling), and Ubiquitin (#3936, 1:1,000; Cell Signaling). Both donkey anti-rabbit and

(5) BMI1 regulates human erythroid self-renewal through both gene repression and gene activationNat CommunAugust 15, 2025Kathleen E. McGrath, Jayme L. Olsen, Anne D. Koniski, Kristin E. Murphy, Michael Getman, Hyun Hyung An, Vincent P. Schulz, Ah Ram Kim, Bin Zhang, Taylor L. Carlson, et al.membrane and stained with primary antibodies including BMI1 (6964S, Cell Signaling Technology), H4 (13919, Cell Signaling Technology), Beta globin (sc-21757, Santa Cruz), Gamma globin (sc-21756, Santa Cruz),

(6) IFI16 Mediates Deacetylation of KSHV Chromatin via Interaction with NuRD and Sin3A Co-Repressor ComplexesVirusesJune 28, 2025Anandita Ghosh, Bala Chandran, Arunava Roy4499); Acetyl-Histone H3 anti-rabbit (Cell Signaling, 8173); Histone H4 anti-rabbit (Cell Signaling, 13919); Acetyl-Histone H4 anti-rabbit (Cell Signaling, 13534); anti-rabbit control IgG (Proteintech, 30000-0-AP);

(7) HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injuryCell Stem CellJune 5, 2025Wei-Chien Yuan, Andrew S. Earl, Sai Ma, Karel Alcedo, Jacquelyn O. Russell, Fabiana M. Duarte, Yen-Ting Chu, Pei-Chi Chang, Hsin-Yi Chen, Hsin-Hui Chi, et al.(Cell Signaling, Cat#9441, 1:1000), Histone 3 (Cell Signaling, Cat#4499S, 1:10000), Histone 4 (Cell Signaling, Cat#13919S, 1:1000), H3K14ac (Cell Signaling, Cat#7627S, 1:1000), and H4K12ac (Millipore Sigma, Cat#07–595, 1:1000).

(8) Salmonella typhi serine threonine kinase T4519 induces lysosomal membrane permeabilization by manipulating toll-like receptor 2-Cystatin B-Cathepsin B-NF-κB-reactive oxygen species pathway and promotes survival within human macrophagesPLoS PathogApril 1, 2025Swarnali Chakraborty, Debayan Ganguli, Theeya Nagaraja, Animesh Gope, Sudip Dey, Ananda Pal, Rahul Shubhra Mandal, Sudipta Sekhar Das, Santasabuj Daswere procured from Cell Signalling Technology: IκBα (cat # 9242S) p65 (cat # 8242S), histone H4 (cat # 13919S), β-actin (cat # 3700S), m-TOR (cat # 2983S), galectin-1 (cat # 12936S), TLR9 (cat #.13674S) and HRP-conjugated

(9) RACK7 Interacts with PRC2 Complex to Regulate Astrocyte DevelopmentAdvanced ScienceMarch 24, 2025Fangfang Jiao, Tianxiang Tang, Bowen Wang, Shengfei He, Yue Zhang, Li Dong, Bo Xu, Ying Liu, Ping Zhu, Rui GuoAnti‐histone H3K27me3 (#9733, Cell signaling technology), Anti‐Histone H3 (ab18521, Abcam), Anti‐Histone H4 (#13919, Cell signaling technology), Anti‐Ezh2(#5246, Cell signaling technology), Anti‐EED (#85322, Cell signaling technology

(10) HTLV-1-infected cells drive the differentiation of monocytes into macrophages in vitroBMC ImmunolMarch 20, 2025Sabrina de Souza, Guilherme Affonso Melo, Carolina Calôba, Maria Clara Salgado Campos, Juliana Vieira Pimenta, Fabianno Ferreira Dutra, Renata Meirelles Pereira, Juliana Echevarria-Limaperformed with rabbit antibodies against GAPDH (cat. n°. 5174, Cell Signaling Technology), H4 (cat. n°. 13919S, clone Cell Signaling Technology) and H2A (cat. n°. 2578S, Cell Signaling Technology). Four-fold concentrated

(11) The impact of circulating nucleosomes on inflammation in acute lung injuryThe FASEB JournalDecember 15, 2024Saugata Dutta, Yin Zhu, Sultan Almuntashiri, Payaningal R. Somanath, Shaheen Islam, Wenbo Zhi, Gustavo Ramírez, Nora Regino, María Jose Leyva‐Zilli, Victoria Muñoz‐Guido, et al.(Cat#12364T, Lot# 3, Cell Signaling Technology), H3 (Cat#4499T, Lot# 9, Cell Signaling Technology), or H4 (Cat#13919T, Lot# 3, Cell Signaling Technology). The membranes were then washed and incubated with HRP‐conjugated

(12) Monoubiquitinated H2B, a Main Chromatin Target of Formaldehyde, Is Important for S‐Phase Checkpoint Signaling and Genome StabilityMolecular CarcinogenesisDecember 1, 2024Sasmita Mishra, Casey Krawic, Michal W. Luczak, Anatoly Zhitkovich(Cell Signaling, 9733), H3K36me3 (Cell Signaling, 4909), H3K79me3 (EpigenTek, A-4045–050), H4 (Cell Signaling, 13919), H4K16ac (Cell Signaling, 13534), H4K12ac (Active Motif, 39165), H4K20me2 (Abcam, ab9052), and H4K20me3

(13) Nuclear localization of MTHFD2 is required for correct mitosis progressionNature CommunicationsNovember 12, 2024Natalia Pardo-Lorente, Anestis Gkanogiannis, Luca Cozzuto, Antoni Gañez Zapater, Lorena Espinar, Ritobrata Ghose, Jacqueline Severino, Laura García-López, Rabia Gül Aydin, Laura Martin, et al.H3K27me3 (Diagenode; #C15410195; 1:1000), H3 (Cell Signaling; #14269S; 1:1000) and H4 (Cell Signaling; #13919; 1:1000). For experiments with whole-cell extracts, these were obtained using an SDS lysis buffer (2%

(14) Aging‐associated reduction of chromosomal histones in mammalian oocytesGenes to CellsOctober 1, 2024Masashi Mori, Manami Koshiguchi, Osamu Takenouchi, Mei A. Mukose, Hinako M. Takase, Tappei Mishina, Hailiang Mei, Miho Kihara, Takaya Abe, Azusa Inoue, et al.(1:100, Active Motif), a mouse anti‐H3.3 (1:20000, Active Motif), and rabbit anti‐H4 antibody (1:200, no. 13919, Cell Signaling). Alexa Fluor 555 goat anti‐mouse IgG (H + L) (A21424) (1:500, Thermo Fisher) was used

(15) Sensitive Detection of Histones and γ-H2AX by Immunoblotting: Problems and SolutionsChemical research in toxicologySeptember 16, 2024Krawic C, Luczak MW, Zhitkovich A.(Cell Signaling, 9733), H3K79me3 (EpigenTek, A-4045–050), H3K27ac (Cell Signaling, 9733), H4 (Cell Signaling, 13919 and Millipore, 07–108), H4K8ac (Cell Signaling, 2576), H4K12ac (Active Motif, 39165), H4K16ac (Abcam,

(16) BMI1 regulates human erythroid self-renewal through both gene repression and gene activationbioRxivFebruary 9, 2024Kathleen E. McGrath, Anne D. Koniski, Kristin Murphy, Michael Getman, Hyun Hyung An, Vincent P. Schulz, Ah Ram Kim, Bin Zhang, Taylor L. Schofield, Julien Papoin, et al.membrane and stained with primary antibodies including BMI1 (6964S, Cell Signaling Technology), H4 (13919, Cell Signaling Technology), Beta globin (sc-21757, Santa Cruz), Gamma globin (sc-21756, Santa Cruz),

(17) Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver diseaseTheranosticsJanuary 1, 2024Yan-Hang Wang, Xin Chen, Yi-Zhen Bai, Peng Gao, Zhuo Yang, Qiang Guo, Ying-Yuan Lu, Jiao Zheng, Dan Liu, Jun Yang, et al.(#9368), PKCμ (#90039), p-PKCδ (#9374), Histone H3 (#4499), Histone H3 (acetyl K9, #9649), Histone H4 (#13919), HA tag (#11846), SCD1 (#2794), β-actin (#3700), rabbit IgG (#7074) and mouse IgG (#7076) were purchased

(18) Neutrophil elastase activates the release of extracellular traps from COPD blood monocyte‐derived macrophagesClinical and Translational ScienceNovember 22, 2023Shuo Zheng, Apparao B. Kummarapurugu, Gamze B. Bulut, Aamer Syed, Le Kang, Judith A. Voynowtemperature, membranes were incubated with rabbit anti‐histone H3 (#4499; CST), or anti‐histone H4 (#13919; CST), or anti‐PAD2 (#97647; CST), or anti‐PAD4 (#684202; Biolegend; 1:1000) antibodies, followed by

(19) Epigenetic dynamics during capacitation of naïve human pluripotent stem cellsScience AdvancesSeptember 29, 2023João Agostinho de Sousa, Chee-Wai Wong, Ilona Dunkel, Thomas Owens, Philipp Voigt, Adam Hodgson, Duncan Baker, Edda G. Schulz, Wolf Reik, Austin Smith, et al.#ab4729), and H3K9me3 (1:1000; Abcam, #ab8898) and for Fig. 3: H4 (1:1000; Cell Signaling Technology, #13919) and H3K27me3 (1:1000; Cell Signaling Technology, #9733). The secondary antibody used were an HRP-conjugated

(20) Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applicationsJournal of extracellular vesiclesAugust 1, 2023Zhang Z, Yu K, You Y, Jiang P, Wu Z, DeTure MA, Dickson DW, Ikezu S, Peng J, Ikezu T.Cell Signaling Technology), anti‐Golgin A2 (GM130, 1:100, #sc‐55591, Santa Cruz Biotechnology), anti‐Histon H4 (1:100, #13919S, Cell Signaling Technology), anti‐EEA1 (1:100, #sc‐137130, Santa Cruz), anti‐ATG9A (1:100, #13509, Cell Signaling Technology

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Histone H4 (D2X4V) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Histone H4 (D2X4V) Rabbit mAb from Cell Signaling Technology

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