Pyk2 (H364) Antibody 3090S from Cell Signaling Technology

Product Specs
ItemPyk2 (H364) Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number3090S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetPyk2
HostRabbit
NCBI Gene AliasesCADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK
NCBI Full Gene Nameprotein tyrosine kinase 2 beta
ClonalityPolyclonal
Research AreaMAP Kinase Signaling
CloneH364
Molecular Weight116

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) VS-4718 enhances apoptosis induced by low-dose carfilzomib and overcomes carfilzomib resistance in PSMB5-mutated proteasome inhibitor resistant multiple myelomaSci RepMarch 16, 2026Ellen Leich-Zbat, Sofia Catalina Heredia-Guerrero, Marietheres Evers, Thorsten Stühmer, Tina Grieb, Hilka Rauert-Wunderlich, Ralf C. Bargou, Andreas Rosenwald, Manik Chatterjee, Daniela Brünnertantibodies from Cell Signaling Technologies (Danvers, MA, USA) against the following targets: PYK2 ((H364), #3090, 1:1000), pPYK2 ((Y402) #3291, 1:2000), FAK ((D2R2E) #13009, 1:1000), pFAK ((Y397) #3283, 1:1000), CASP9

(2) Glycoprotein NMB mediates bidirectional GSC-TAM interactions to promote tumor progressionJCI InsightJuly 8, 2025Yang Liu, Lizhi Pang, Fatima Khan, Junyan Wu, Fei Zhou, Craig Horbinski, Shideng Bao, Jennifer S. Yu, Justin D. Lathia, Peiwen Chen(Cell Signaling Technology, 9355S), P-PYK2 (Cell Signaling Technology, 3291S), PYK2 (Cell Signaling Technology, 3090S), and CD44 (Cell Signaling Technology, 37259S). Brain tumor immune cell isolation. At the endpoint

(3) The olfactory receptor OR51E2 activates ERK1/2 through the Golgi-localized GÎ²Î³-PI3KÎ³-ARF1 pathway in prostate cancer cellsFrontiers in PharmacologyOctober 13, 2022Xin Xu, Mostafa Khater, Guangyu WuBD Biosciences. Rabbit polyclonal anti-ERK1/2 antibodies (9102) were from Cell Signaling Technology. Gallein (3090) was from Tocris Bioscience. AS-604850 (B2181) was from ApexBio. Plasmid construction FLAG-tagged

(4) The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancerThe Journal of biological chemistryNovember 1, 2021Diehl JN, Klomp JE, Snare KR, Hibshman PS, Blake DR, Kaiser ZD, Gilbert TSK, Baldelli E, Pierobon M, Papke B, et al.The following antibodies were obtained from Cell Signaling Technology: anti-DDR1 (5583S), anti-PYK2 (3090S), anti-STAT3 (9139S), antiphosphorylated STAT3 Tyr705 (9145S), anti-WEE1 (13084S), anti-CHK1 (2360S),

(5) Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9Current Research in Chemical BiologyAugust 28, 2021SeongShick Ryu, Gillian E. Gadbois, Andrew J. Tao, Benjamin J. Fram, Jie Jiang, Bridget Boyle, Katherine A. Donovan, Noah M. Krupnick, Bethany C. Berry, Debabrata Bhunia, et al.(Cell Signaling #13331T), NEK9 (Abcam #ab138488), Wee1 (Cell Signaling #13084T), PTK2B (Cell Signaling #3090S), and Tubulin (Cell Signalling #3873S) at 4 °C overnight. DyeLight800-labeled goat anti-rabbit IgG (Cell Signalling

(6) A high-speed, high-performance, microfabricated comprehensive two-dimensional gas chromatographLab on a ChipMarch 29, 2019Joshua J. Whiting et al.leaks, unimpeded flow, and a continuous channel seal. The columns were then statically coated. The 3090 columns were coated using a solution of —9.7 mg of 25 000 cSt vinyl-terminated PDMS (Gelest, Inc. Morrisville,

(7) PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-Catenin^Y654Cellular and molecular gastroenterology and hepatologyJanuary 1, 2019Gao C, Chen G, Zhang DH, Zhang J, Kuan SF, Hu W, Esni F, Gao X, Guan JL, Chu E, et al.(IB) β-actin,"Santa Cruz Biotechnology (Dallas, TX)",sc-81178,1:2000 (IB) PYK2,Cell Signaling Technology,3090,1:1000 (IB) PYK2,Santa Cruz Biotechnology,sc-1515,1:25 (IHC) p-PYK2Y402,Thermo Fisher Scientific,44-618G,"1:50

(8) Suppression of Abdominal Aortic Aneurysm Formation in Mice by Teneligliptin, a Dipeptidyl Peptidase-4 InhibitorJournal of Atherosclerosis and ThrombosisAugust 1, 2018Yusuke Takahara, Tomotake Tokunou, Toshihiro Ichikiantibody against MAC2 (CL8942AP), Ang II (4001), Glycyl-L-proline 4-methylcoumaryl-7-amide (Gly-Pro-MCA, 3090-v), and 7-Amino-4-methylcoumarin (AMC, 3099-v) were purchased from Peptide institute Inc. (Osaka, Japan).

(9) OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiencyMolecular psychiatryFebruary 1, 2018Ullrich M, Weber M, Post AM, Popp S, Grein J, Zechner M, Guerrero González H, Kreis A, Schmitt AG, Üçeyler N, et al.

(10) Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca²⁺ entry regulates disassembly of adherens junctionsAmerican journal of physiology. Lung cellular and molecular physiologyJune 1, 2017Soni D, Regmi SC, Wang DM, DebRoy A, Zhao YY, Vogel SM, Malik AB, Tiruppathi C.IL). Rabbit pAb specific to phospho-Pyk2 Y402 (cat. no. 3291) (48), rabbit pAb against Pyk2 (cat. no. 3090) (32), rabbit mAb against phospho-Src Y416 (cat. no. 6943) (24), and rabbit mAb against Src (cat. no.

(11) Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infectionPLoS pathogensMay 1, 2017Iampietro M, Younan P, Nishida A, Dutta M, Lubaki NM, Santos RI, Koup RA, Katze MG, Bukreyev A.TRAM1 (FabGennix #PTRAM-140AP), MyD88 (#4283S), IRAK4 (#4363S), phosphorylated IRAK4 (#11927S), Pyk2 (#3090S), phosphorylated Pyk2 (#3291S), p38 (#8690S), phosphorylated p38 (#4511S), NFκB (#6956S), phosphorylated

(12) Achievement of a target dose of bisoprolol may not be a preferred option for attenuating pressure overload-induced cardiac hypertrophy and fibrosisExperimental and therapeutic medicineOctober 1, 2016Xiang S, Zhang N, Yang Z, Bian Z, Yuan Y, Tang Q.

(13) Regulator of G protein signalling 14 attenuates cardiac remodelling through the MEK-ERK1/2 signalling pathwayBasic research in cardiologyJuly 1, 2016Li Y, Tang XH, Li XH, Dai HJ, Miao RJ, Cai JJ, Huang ZJ, Chen AF, Xing XW, Lu Y, et al.

(14) CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasisOncogeneJune 2, 2016Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, Richter JD.

(15) Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma CellsPLoS ONEJune 28, 2012Marco Genua, Shi-Qiong Xu, Simone Buraschi, Stephen C. Peiper, Leonard G. Gomella, Antonino Belfiore, Renato V. Iozzo, Andrea Morrionepost-transfection. siRNA efficiency was detected by immunobloting using anti-FAK (#3285) and anti-Pyk2 (#3090) polyclonal antibodies (both from Cell Signaling Technology, Beverly, MA, USA). ß-actin was detected

(16) Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growthNature communicationsJanuary 1, 0001"Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, et al."1:2000) and Tyro3 (5585, Cell Signalling, 1:1000), Cyr61 (ABC102, Millipore, 5 μg/ml), Pyk2 and p-Pyk2 (3090, 3291, Cell Signalling, 1:1000), Src and p-Src (2108, 6943, Cell Signalling, 1:1000), Tubulin (T5168,

(17) Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null GliomaCancer cellJanuary 1, 0001"Chen P, Zhao D, Li J, Liang X, Li J, Chang A, Henry VK, Lan Z, Spring DJ, Rao G, et al."AKT, #2910S; T416P-SRC, #6943S; SRC, #2109S; Notch1, #4380S; YAP1, #14074S; T402P-PYK2, #3291S; PYK2, #3090S; T397P-FAK, #3283S;FAK, #3285S; T1068P-EGFR, #3777S and EGFRviii, #64952S), Abcam (LOX, #ab174316; CXCL5,

(18) A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase DegraderCell chemical biologyJanuary 1, 0001"Huang HT, Dobrovolsky D, Paulk J, Yang G, Weisberg EL, Doctor ZM, Buckley DL, Cho JH, Ko E, Jang J, et al.",Cell Signaling Technology,Cat#12741T; RRID: AB_2617131 Rabbit polyclonal anti-Pyk2 (H364),Cell Signaling Technology,Cat#3090S; RRID: AB_2174095 Mouse monoclonal anti-α-tubulin (DM1A),Cell Signaling Technology,Cat#3873S; RRID:

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Pyk2 (H364) Antibody

Pyk2 (H364) Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Pyk2 (H364) Antibody from Cell Signaling Technology

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