HXK II (1A7) Antibody sc-130358 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHXK II (1A7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-130358
NCBI Gene AliasesHKII, HXK2
Antibody TypePrimary Antibodies
Clone1A7
Quantity50 µg/500 µl
ClonalityMonoclonal
ApplicationsWB, IP, ELISA
FormatPurified
Hostmouse
Conjugate/TagUnconjugated
Reactivitymouse, rat, human
NCBI Full Gene Namehexokinase 2
TargetHXK II
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) HHEX-PRKAR2B axis-mediated PKA activation drives glucose metabolism-dependent progression of pancreatic ductal adenocarcinomaiScienceFebruary 20, 2026Wen J, Li Q, Xu S, Lu W, Wu F, Lou J, Wang L.cat. ab32096, Abcam), KLF5 (1:1000, cat. sc-398014, Santa Cruz Biotechnology), and HK2 (1:1000, cat. sc-130358, Santa Cruz Biotechnology). Horseradish peroxidase (HRP)-conjugated anti-rabbit IgG (1:3000, cat. 7074,

(2) Targeting Glycolysis with 2-Deoxy-D-Glucose and Lysosomal Integrity with L-Leucyl-L-Leucine Methyl Ester as Antimelanoma StrategyPharmaceuticsOctober 9, 2025Kosic M, Bosnjak M, Mandic M, Vucicevic L, Marjanovic MM, Poulsen SE, Harhaji-Trajkovic L.(all from Cell Signaling Technology, Beverly, MA, USA), or anti-cathepsin C (sc-74590) and anti-HK2 (sc-130358) (both from Santa Cruz Biotechnology). β-Actin (#4967S, Cell Signaling Technology) and glyceraldehyde-3-phosphate

(3) The Antitumor Role of Incomptine A in a Breast Cancer Murine Model: Impairment of Hexokinase II Expression and Apoptosis InductionCellsAugust 2, 2025Angel Giovanni Arietta-García, Fernando Calzada, Antonio Franco-Vadillo, Irais Monserrat Barrientos-Buendía, Francisco Javier Alarcón-Aguilar, Elihú Bautista, Paola Santana-Sánchez, Israel Ramírez-Sánchez, Rosa María Ordoñez-Razoprimary antibodies against hexokinase II (HKII) (1:2500, Santa Cruz Biotechnology, Dallas, TX, USA. sc-130358), aldolase A (ALDOA) (1:2500, Santa Cruz Biotechnology, Dallas, TX, USA. sc-390733), lactate dehydrogenase

(4) Asymmetric cell division of ALDH1-positive cancer stem cells generates glycolytic metabolically diverse cell populationsSci RepApril 22, 2025Shoma Tamori, Chika Matsuda, Takahiro Kasai, Shigeo Ohno, Kazunori Sasaki, Kazunori Akimoto1:500), PFKP (D2E5) rabbit mAb (Cell Signaling, 12746S, 1:500), HXK II (1A7) mouse mAb (Santa Cruz, sc-130358, 1:500), and PKM2 XP® rabbit mAb (Cell Signaling, 4053S, 1:500). The secondary antibodies used were

(5) Effects of seven days' fasting on physical performance and metabolic adaptation during exercise in humansNature communicationsJanuary 2, 2025Kolnes KJ, Nilsen ETF, Brufladt S, Meadows AM, Jeppesen PB, Skattebo Ø, Johansen EI, Birk JB, Højlund K, Hingst J, et al.Prof. D. G. Hardie (University of Dundee, Scotland, UK). Commercial antibodies against Hexokinase II (sc-130358) and AMPKα2 (sc-19131) were from Santa Cruz Biotechnology, while antibodies against citrate synthase

(6) GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control studyEBioMedicineNovember 1, 2023Tramutola A, Bakels HS, Perrone F, Di Nottia M, Mazza T, Abruzzese MP, Zoccola M, Pagnotta S, Carrozzo R, de Bot ST, et al.1:1000, RRID: AB_301846), Rab11-A (sc-166912, Santa Cruz Biotec., 1:1000, RRID: AB_10611645), HK-II (sc-130358, Santa Cruz, 1:1000, RRID:AB_2295219), OXPHOS (Ab110411, Abcam, 1:5000, RRID:AB_2756818), NDUFUB8 (NBP2-75586,

(7) Advances in the Properties of Incomptine A: Cytotoxic Activity and Downregulation of Hexokinase II in Breast Cancer Cell LinesInt J Mol SciAugust 3, 2023Angel Giovanni Arietta-García, Fernando Calzada, Israel Ramírez-Sánchez, Elihú Bautista, Normand García-Hernandez, Rosa María Ordoñez-Razofollowing protein-specific antibodies overnight at 4 °C: mouse anti-HKII (1:2500, Santa Cruz Biotechnology, sc-130358), mouse anti-ALDOA (1:2500, Santa Cruz Biotechnology, sc-390733), and mouse anti-LDH (1:2500, Santa Cruz Biotechnology

(8) Prox1 Suppresses the Proliferation of Breast Cancer Cells via Direct Inhibition of c-Myc Gene ExpressionCellsJuly 17, 2023Michail A, Gkikas D, Stellas D, Kaltezioti V, Politis PK.antibodies we used were rabbit anti-c-Myc (Abcam, ab32072, Waltham, Boston), mouse anti-HK2 (Santa Cruz, sc-130358, Dallas, TX, USA), rabbit anti PDK1 (proteintech 10026-1-AP, Rosemont, IL, USA), mouse anti-MPC1 (proteintech

(9) Leucine and Arginine Availability Modulate Mouse Embryonic Stem Cell Proliferation and MetabolismInternational journal of molecular sciencesNovember 18, 2022Correia B, Sousa MI, Branco AF, Rodrigues AS, Ramalho-Santos J.1:1000),rabbit anti-PKM2 (Cat.No:ab137852, Abcam, Cambridge, UK; 1:250), mouse anti-HXK II (Cat.No:sc-130358, Santa Cruz, Dallas, TX, USA; 1:200), mouse anti-PDH-E1alpha (Cat.No:sc-377092, Santa Cruz, Dallas,

(10) Iron controls T helper cell pathogenicity by promoting glucose metabolism in autoimmune myopathyClinical and translational medicineAugust 1, 2022Lai Y, Zhao S, Chen B, Huang Y, Guo C, Li M, Ye B, Wang S, Zhang H, Yang N.wet transfer method. Membranes were incubated with the antibodies against HK2 (Santa Cruz, USA, Cat sc‐130358, 1:500), PFKFB4 (Abcam, Hong Kong, Cat ab137785, 1:2000), T‐bet (Abcam, Hong Kong, Cat ab181400, 1:1000),

(11) 17-β Estradiol up-regulates energy metabolic pathways, cellular proliferation and tumor invasiveness in ER+ breast cancer spheroidsFrontiers in oncologyJanuary 1, 2022Pacheco-Velázquez SC, Ortega-Mejía II, Vargas-Navarro JL, Padilla-Flores JA, Robledo-Cadena DX, Tapia-Martínez G, Peñalosa-Castro I, Aguilar-Ponce JL, Granados-Rivas JC, Moreno-Sánchez R, et al.

(12) Regulatory role of acetylation on enzyme activity and fluxes of energy metabolism pathwaysBiochimica et biophysica acta. General subjectsDecember 1, 2021Moreno-Sánchez R, Gallardo-Pérez JC, Pacheco-Velazquez SC, Robledo-Cadena DX, Rodríguez-Enríquez S, Encalada R, Saavedra E, Marín-Hernández Á.

(13) Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthaseNature communicationsAugust 10, 2021Carrer A, Tommasin L, Šileikytė J, Ciscato F, Filadi R, Urbani A, Forte M, Rasola A, Szabò I, Carraro M, et al.(14671, Cell Signaling), anti-ANT3 (PA5-35113, ThermoFischer), anti-OXPHOS (ab110411, Abcam), anti-HKII (sc130358, Santa Cruz), anti-UQCRC1 (sc65238, Santa Cruz), anti-Grim19 (sc271013, Santa Cruz), and anti-SDHA (sc166947,

(14) Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndromeFree radical biology & medicineMarch 1, 2021Lanzillotta C, Tramutola A, Di Giacomo G, Marini F, Butterfield DA, Di Domenico F, Perluigi M, Barone E.

(15) Contribution of the CK2 Catalytic Isoforms α and α'' to the Glycolytic Phenotype of Tumor CellsCellsJanuary 18, 2021Zonta F, Borgo C, Quezada Meza CP, Masgras I, Rasola A, Salvi M, Pinna LA, Ruzzene M.

(16) Metabolic characterization of a paused-like pluripotent stateBiochimica et biophysica acta. General subjectsAugust 1, 2020Sousa MI, Correia B, Rodrigues AS, Ramalho-Santos J.

(17) Hypoxic Exposure Increases Energy Expenditure by Increasing Carbohydrate Oxidation in MiceBioMed Research InternationalJune 24, 2020Yeram Park, Deunsol Hwang, Hun-Young Park, Jisu Kim, Kiwon Lim(1 : 1000, an38242), PGC1α (1 : 1000, ab54481) or mouse anti-rat β-actin (1 : 1000, sc47778), HK2 (1 : 1000, sc130358), and PDH (1 : 1000, sc377092) overnight at 4°C. Membranes were then incubated with the relevant secondary antibodies

(18) Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancerMolecular oncologyJune 1, 2020Wu J, Chai H, Xu X, Yu J, Gu Y.anti‐HIF1α (BD, Franklin lake, NJ, USA, Cat#610959), anti‐HK2 (Santa Cruz, Santa Cruz, CA, USA, Cat#sc‐130358), anti‐LDHA (Santa Cruz, Cat#sc‐133123), anti‐PCNA (CST, Danvers, MA, USA, Cat#2586s), Flag (Sigma,

(19) The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transportPhysiological reportsJune 1, 2020Møller LLV, Nielsen IL, Knudsen JR, Andersen NR, Jensen TE, Sylow L, Richter EA.,Thermo Fisher Scientific; PA1−1065,Rabbit; Polyclonal antibody,"1:1,000",2% milk HKII,AB_2295219,Santa Cruz Biotechnology; Sc−130358,Mouse; Monoclonal antibody,"1:1,000",2% milk PAK1,AB_330222,"Cell Signaling Technology; 2,602",Rabbit;

(20) Brain insulin resistance triggers early onset Alzheimer disease in Down syndromeNeurobiology of diseaseApril 1, 2020Tramutola A, Lanzillotta C, Di Domenico F, Head E, Butterfield DA, Perluigi M, Barone E.

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HXK II (1A7) Antibody

HXK II (1A7) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HXK II (1A7) Antibody from Santa Cruz Biotechnology, Inc.

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