Brilliant Violet 570™ anti-human CD4 300534 from BioLegend

Product Specs
ItemBrilliant Violet 570™ anti-human CD4
CompanyBioLegend
Price $429.00Supplier Page View Company Product Page
Catalog Number300534
Quantity100 tests
ApplicationsFC - Quality tested
Conjugate/TagBrilliant Violet 570™
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ReactivityHuman
IsotypeMouse IgG1, kappa
CloneRPA-T4
HostMouse
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ClonalityMonoclonal
TargetCD4
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)

Add to Compare List

BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) IL-12-engineered human PSMA-CAR T cells for the treatment of advanced prostate cancerMolecular Therapy AdvancesJune 11, 2026Lupita S. Lopez, Ziyou Cui, Yukiko Yamaguchi, John P. Murad, Zhiyuan Yang, Ke Zou, Jason Yang, Wen-Chung Chang, Stephen J. Forman, Vivien W. Chan, et al.human antigens used include: CD3 (BD Biosciences, Cat: 563109, Clone: SK7), CD4 (BD BioLegend, Cat: 300534, Clone: RPA-T4), CD8 (Invitrogen, Cat: 56-008-742, Clone: SK1), CD19 (BD Biosciences, Cat: 557835, Clone:

(2) HIV broadly neutralizing antibody escape dynamics drive the outcome of AAV-vectored immunotherapy in humanized miceImmunityMarch 10, 2026Nicolas M.S. Galvez, Adam D. Nitido, Seo Bin Yoo, Yi Cao, Cailin E. Deal, Christine L. Boutros, Scott W. MacDonald, Yentli E. Soto Soto Albrecht, Evan C. Lam, Maegan L. Sheehan, et al.flow cytometry to determine the baseline CD3+ (BioLegend, Cat#300434 - RRID:AB_10962690), CD4+ (BioLegend, Cat#300534 - RRID: AB_2563791), and CD8+ (BioLegend, Cat#300554 - RRID: AB_2564382) T cells engraftment. The next

(3) Oncogenic roles of young human de novo genes and their potential as neoantigens in cancer immunotherapyCell GenomicsSeptember 10, 2025Chunfu Xiao, Xiaoge Liu, Peiyu Liu, Xinwei Xu, Chao Yao, Chunqiong Li, Qi Xiao, Tiannan Guo, Li Zhang, Yongjun Qian, et al.FITC anti-human CD45,Biolegend,Cat#304005; RRID: AB_314393 Brilliant Violet 570 anti-human CD4,Biolegend,Cat#300533; RRID: AB_10896788 Brilliant Violet 421 anti-human CD137 (4-1BB),Biolegend,Cat#309819; RRID: AB_10895902 PE-Cy7

(4) Coupling IL-2 with IL-10 to mitigate toxicity and enhance antitumor immunityCell Reports MedicineAugust 19, 2025Julie J. Ahn, Steven Dudics, David P. Langan, Jeffrey D. Smith, Alice H. Hsu, Jacob C. McCright, Sawyer R. Smith, Alicia L. Castleberry, Benjamin I. George, Javier A. Goitía Vázquez, et al.T cell subsets were identified using previously described phenotypic markers,33 anti-human CD4 BV570 (Biolegend, 300534), CD45RA BV480 (BD, 566114) CD45RO BUV805 (BD, 748367), CD25 BUV661 (BD, 741685), CD95 BUV615 (BD, 752346),

(5) Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18Nat CommunJuly 2, 2025Fanfan Fan, Jun Wang, Kun Liu, Shiyue Zhang, Jian Gao, Xiongfei Li, Jiaqiang Ma, Yue Zhao, Teng Li, Han Su, et al.The following antibodies were used: anti-CD3D BUV395 (BD, Cat#564001), anti-CD4 BV570 (Biolegend, Cat#300534), anti-CD8 AF700 (BD, Cat#557945), anti-CD25 APC (Biolegend, Cat#302610), anti-CD127 BV421 (Biolegend,

(6) A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint TherapiesMolecular Cancer TherapeuticsJuly 2, 2025Keith Abayasiriwardana, Lei Wu, Hanane Laklai, Malgorzata Nocula-Lugowska, Lioudmila Tchistiakova, Jatin Narula, Amy Jackson-Fisher, Jonathon Golas, My-Hanh Lam, Veronika Grinstein, et al.MDA-MB-468 tumor studies consisted of Brilliant Violet 570 anti-human CD4 antibody (BioLegend, Cat. # 300533, RRID:AB_10896788), Brilliant Violet 605 anti-human CD3 antibody (BioLegend, Cat. # 317321, RRID:AB_11126166),

(7) Disrupted priming within draining lymph nodes drives immune quiescence in gastric cancerbioRxivMay 25, 2025Sohrab Salehi, Emily E. Stroobant, Hannah Lees, Ya-Hui Lin, Shoji Shimada, Miseker Abate, Matthew J. Zatzman, Nicholas Ceglia, Samuel S. Freeman, Monika Laszkowska, et al.collected and stained with a viability dye followed by surface staining with anti-CD4 (RPA-T4, BioLegend 300534, 1:100), anti-CD8 (RPA-T8, BD Biosciences 612914, 1:1200), TotalSeq-A Human Universal Cocktail, and

(8) A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint TherapiesMol Cancer TherMay 14, 2025Keith Abayasiriwardana, Lei Wu, Hanane Laklai, Malgorzata Nocula-Lugowska, Lioudmila Tchistiakova, Jatin Narula, Amy Jackson-Fisher, Jonathon Golas, My-Hanh Lam, Veronika Grinstein, et al.MDA-MB-468 tumor studies consisted of Brilliant Violet 570 anti-human CD4 antibody (BioLegend, Cat. # 300533, RRID:AB_10896788), Brilliant Violet 605 anti-human CD3 antibody (BioLegend, Cat. # 317321, RRID:AB_11126166),

(9) BH3 mimetics augment cytotoxic T cell killing of acute myeloid leukemia via mitochondrial apoptotic mechanismCell Death DiscovMarch 26, 2025Kapil Saxena, Shao-Hsi Hung, Esther Ryu, Shailbala Singh, Qi Zhang Tatarata, Zhihong Zeng, Zhe Wang, Marina Y. Konopleva, Cassian YeeAntibody/fluorophore,Company,Catalog "CD3, Brilliant Violet 785 (BV785)",Biolegend,344842 "CD4, BV570",Biolegend,300534 "CD8, APC",Biolegend,344722 "CD16, PE",Biolegend,302008 "CD34, APC",Biolegend,343509 "CD38, APC-Cy7",Biolegend,356615 "CD45,

(10) BH3 Mimetics Augment Cytotoxic T Cell Killing of Acute Myeloid Leukemia via Mitochondrial Apoptotic MechanismResearch squareDecember 9, 2024Yee C, Saxena K, Ryu E, Hung SH, Singh S, Zhang Q, Zeng Z, Wang Z, Konopleva M.Antibody/fluorophore,Company,Catalog "CD3, Brilliant Violet 785 (BV785)",Biolegend,344842 "CD4, BV570",Biolegend,300534 "CD8, APC",Biolegend,344722 "CD16, PE",Biolegend,302008 "CD34, APC",Biolegend,343509 "CD38, APC-Cy7",Biolegend,356615 "CD45,

(11) Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infectionNature communicationsApril 17, 2024Phetsouphanh C, Jacka B, Ballouz S, Jackson KJL, Wilson DB, Manandhar B, Klemm V, Tan HX, Wheatley A, Aggarwal A, et al.[1:100]), CD25 (2A3, #340939 [1:20]), and CD19 (HIB19, #557921 [1:100]) (BioLegend, USA); CD4 (OKT4, 300533 [1:100]), CD127 (A019D5, #351325 [1:100]), HLA-DR (L234, #307671 [1:100]), CCR7 (G043H7, 353217 [1:100]),

(12) Immunomodulatory response to neoadjuvant nivolumab in non-metastatic clear cell renal cell carcinomaScientific reportsJanuary 17, 2024Singla N, Nirschl TR, Obradovic AZ, Shenderov E, Lombardo K, Liu X, Pons A, Zarif JC, Rowe SP, Trock BJ, et al.65-0865-14), followed by fluorophore conjugated antibodies specific for human CD4 (BV570 Biolegend, Cat 300534), CD8 (BV650 Biolegend, Cat # 301041), PD-1 (PE-Cy7 Biolegend, Cat # 329918) and CD3 (AF700 BD Biosciences,

(13) Decoding NY-ESO-1 TCR T cells: transcriptomic insights reveal dual mechanisms of tumor targeting in a melanoma murine xenograft modelFrontiers in immunologyJanuary 1, 2024Alsalloum A, Alrhmoun S, Perik-Zavosdkaia O, Fisher M, Volynets M, Lopatnikova J, Perik-Zavodskii R, Shevchenko J, Philippova J, Solovieva O, et al.anti-CD8-PeCy7 (BioLegend Cat# 344712), anti-CD3-AF700 (BioLegend Cat# 300324), anti-CD4-Bv570 (BioLegend Cat# 300534), anti-CD45RA-Bv711 (BioLegend Cat# 304138), anti-CD62L-AF488 (BioLegend Cat# 304816), anti-CD95(Fas)-PerCPP-Cy5.5

(14) TCR-Engineered Lymphocytes Targeting NY-ESO-1: In Vitro Assessment of Cytotoxicity against TumorsBiomedicinesOctober 16, 2023Alaa Alsalloum, Saleh Alrhmoun, Julia Shevchenko, Marina Fisher, Julia Philippova, Roman Perik-Zavodskii, Olga Perik-Zavodskaia, Julia Lopatnikova, Vasily Kurilin, Marina Volynets, et al.anti-CD107a-APC/Cyanine7 (cat#328630), anti-CD3-AF700 (cat #300324), anti-CD8-PeCy7 (cat #344712), anti-CD4-Bv570 (cat #300534), CD137(4-1BB)-BV711TM (cat #309832), anti-CD154 (CD40L)-PerCP/Cy5 (cat #310834), anti-CD69-AF647 (cat

(15) Viral competition assay to assess the role of HIV-1 proteins in immune evasionSTAR ProtocolsMarch 1, 2023Gabriel Duette, Samantha Cronin, Anthony D. Kelleher, Sarah Palmer(1:100)",BD Biosciences,612940 "Brilliant Violet 570™ Anti-Human CD4, Clone RPA-T4 (1:100)",BioLegend,300534 "PerCP-Cy™5.5 Mouse Anti-Human CD8, Clone RPA-T8 (1:100)",BD Biosciences,560662 ,, "Chemicals, peptides,

(16) Reference long-read isoform-aware transcriptomes of 4 human peripheral blood lymphocyte subsetsG3 (Bethesda, Md.)November 4, 2022Woolley CR, Chariker JH, Rouchka EC, Ford EE, Hudson EA, Waigel SJ, Smith ML, Mitchell TC.monocyte "BD, 560367",CD45,+,+,+,+,+,+,+,+,+ "ThermoFisher, 58-0038-42",CD3,+,+,+,+,+,−,−,, "BioLegend, 300534",CD4,+,,,,−,,−,, "ThermoFisher, 64-0088-42",CD8,,,+,+,−,,−,, "BD, 564057",CD56,,+,,+,,+,−,, "BD,

(17) Cellular and humoral functional responses after BNT162b2 mRNA vaccination differ longitudinally between naive and subjects recovered from COVID-19Cell reportsJanuary 11, 2022Lozano-Rodríguez R, Valentín-Quiroga J, Avendaño-Ortiz J, Martín-Quirós A, Pascual-Iglesias A, Terrón-Arcos V, Montalbán-Hernández K, Casalvilla-Dueñas JC, Bergón-Gutiérrez M, Alcamí J, et al.(clone UCHT1),Biolegend,Cat# 300436; RRID:AB_2562124 Anti-human CD4 BV570 (clone RPA-T4),Biolegend,Cat# 300534; RRID:AB_2563791 Anti-human CD4 cFluor-YG584 (clone K3),Cytek Biosciences,Cat# R7-20042; RRID: AB_2885083 Anti-human

(18) Panel Optimization for High-Dimensional Immunophenotyping Assays Using Full-Spectrum Flow CytometryCurr ProtocSeptember 1, 2021Ferrer-Font L, Small SJ, Lewer B, Pilkington KR, Johnston LK, Park LM, Lannigan J, Jaimes MC, Price KM.

(19) In vitro co-culture of human intestinal organoids and lamina propria-derived CD4⁺ T cellsSTAR protocolsJune 18, 2021Schreurs RRCE, Baumdick ME, Drewniak A, Bunders MJ.CCR7-PE-Cy7 (3D12),BD Pharmingen,Cat# 560922; RRID: AB_10561680 Anti-human CD4-BV570 (RPA-T4),BioLegend,Cat# 300533; RRID: AB_10896788 Live-Dead Fixable Red Dead Cell Stain Kit,Invitrogen,Cat# L23102 ,, Biological

(20) Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assayCytotherapyJanuary 1, 2021Lazarski CA, Datar AA, Reynolds EK, Keller MD, Bollard CM, Hanley PJ.

Be the First to Write a Review!

Brilliant Violet 570™ anti-human CD4 from BioLegend

Description

BioLegend

Citations (29)

Reviews

Brilliant Violet 570™ anti-human CD4 from BioLegend

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map