CD5 Antibody (CD5/54/F6) [Alexa Fluor® 488] NBP2-34593AF488 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemCD5 Antibody (CD5/54/F6) [Alexa Fluor® 488]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $559.00Supplier Page View Company Product Page
Catalog NumberNBP2-34593AF488
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Full Gene NameCD5 molecule
NCBI Gene AliasesLEU1, T1
Research AreaAdaptive Immunity, Cell Biology, Cytokine Research, Immunology
PurityProtein A or G purified
ReactivityHu, Rb, Rt, Bv, Ck, GP, Hr, Mk, Pg
ClonalityMonoclonal
ApplicationsFCM, IHC, IHC-p
ImmunogenRecombinant fragment (around aa450-495) of human CD5 protein (intracellular region). (Uniprot: P06127 )
HostMouse
CloneCD5/54/F6
IsotypeIgG1 Kappa
TargetCD5
Format50mM Sodium Borate
Conjugate/TagAlexa Fluor 488
Quantity0.1 ml

Specifications/Features

Available conjugates: Available conjugates: Allophycocyanin, Alexa Fluor 488

Specificity: Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Sizes Available: 0.1 ml

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