Chorionic Gonadotropin beta Chain (hCG beta) Antibody (SPM105) [Alexa Fluor® 488] NBP2-34392AF488 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemChorionic Gonadotropin beta Chain (hCG beta) Antibody (SPM105) [Alexa Fluor® 488]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberNBP2-34392AF488
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Gene AliasesCGB, CGB5, CGB7, CGB8, LHB, hCGB
NCBI Full Gene Namechorionic gonadotropin subunit beta 3
Research AreaCancer
PurityProtein A or G purified
ReactivityHuman (Hu)
ClonalityMonoclonal
ApplicationsIHC, IHC-p
ImmunogenRecombinant Chorionic Gonadotropin beta Chain (hCG beta) protein (Uniprot: P01233)
HostMouse
CloneSPM105
IsotypeIgG1 Kappa
TargetChorionic Gonadotropin beta Chain (hCG beta)
Format50mM Sodium Borate
Conjugate/TagAlexa Fluor 488
Quantity0.1 ml

Specifications/Features

Available conjugates: Available conjugates: DyLight 755, Alexa Fluor 488

Specificity: This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Sizes Available: 0.1 ml

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