Vimentin Antibody (SPM576) [Alexa Fluor® 488] from Novus Biologicals, a Bio-Techne Brand

Available conjugates: Available conjugates: Janelia Fluor 525, DyLight 680, DyLight 755, mFluor Violet 500 SE, FITC, mFluor Violet 610 SE, CoraFluor 1, Alexa Fluor 488, Biotin, DyLight 550, PE, Alexa Fluor 594, DyLight 405, PerCP, Alexa Fluor 405, DyLight 488, DyLight 650, Alexa Fluor 700, Janelia Fluor 646

Specificity: This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Sizes Available: 0.1 ml