HSP27 Antibody (SPM252) [Alexa Fluor® 700] NBP2-34751AF700 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemHSP27 Antibody (SPM252) [Alexa Fluor® 700]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberNBP2-34751AF700
Quantity0.1 ml
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,CyTOF-ready,Immunocytochemistry/ Immunofluorescence
Conjugate/TagAlexa Fluor 700
Format50mM Sodium Borate
ReactivityChicken,Chimpanzee,Human,Mouse,Rat,Sheep
TargetHSP27
IsotypeIgG1 Kappa
CloneSPM252
HostMouse
ImmunogenPartially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells
ClonalityMonoclonal
PurityProtein A or G purified
Research AreaCancer, Cell Biology, Cell Cycle and Replication, Golgi Apparatus Markers, Membrane Trafficking and Chaperones, Neuroscience
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Full Gene Nameheat shock protein family B (small) member 1
NCBI Gene AliasesCMT2F, HEL-S-102, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27

Specifications/Features

Available conjugates: Available conjugates: Janelia Fluor 525, Alexa Fluor 350, Alexa Fluor 405, DyLight 594, mFluor Violet 500 SE, FITC, Alexa Fluor 647, mFluor Violet 450 SE, Biotin, Janelia Fluor 669, PE, PerCP, Janelia Fluor 549, DyLight 755, Alexa Fluor 700

Specificity: It recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced p29 and 24K protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.

Sizes Available: 0.1 ml

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