Supplier Page from Novus Biologicals, a Bio-Techne Brand for Bax Antibody (SPM336) [Alexa Fluor® 488]
Available conjugates: Available conjugates: DyLight 350, HRP, DyLight 650, DyLight 405, DyLight 488, DyLight 755, Alexa Fluor 488Specificity: Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.Sizes Available: 0.1 ml