p27/Kip1 Antibody (SPM348) [Alexa Fluor® 488] NBP2-34766AF488 from Novus Biologicals, a Bio-Techne Brand

Product Specs
Itemp27/Kip1 Antibody (SPM348) [Alexa Fluor® 488]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberNBP2-34766AF488
Quantity0.1 ml
ApplicationsImmunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,Immunocytochemistry/ Immunofluorescence
Conjugate/TagAlexa Fluor 488
Format50mM Sodium Borate
ReactivityHuman,Monkey,Mouse,Rat
Targetp27/Kip1
IsotypeIgG1 Kappa
CloneSPM348
HostMouse
ImmunogenPurified GST-p27 fusion protein of Mouse origin (Uniprot: P46527)
ClonalityMonoclonal
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Full Gene Namecyclin dependent kinase inhibitor 1B
NCBI Gene AliasesCDKN4, KIP1, MEN1B, MEN4, P27KIP1
Research AreaBreast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Prostate Cancer, Tumor Suppressors
PurityProtein A or G purified

Specifications/Features

Available conjugates: Available conjugates: Alexa Fluor 350, Alexa Fluor 647, DyLight 488, HRP, Alexa Fluor 700, Janelia Fluor 549, Alexa Fluor 532, DyLight 650, Alexa Fluor 488

Specificity: This monoclonal antibody recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This monoclonal antibody is excellent for staining of formalin-fixed tissues.

Sizes Available: 0.1 ml

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