Supplier Page from Novus Biologicals, a Bio-Techne Brand for Kappa Light Chain Antibody (KLC264) [Alexa Fluor® 647]
Available conjugates: Available conjugates: PE/Atto594, CoraFluor 1, DyLight 550, Alexa Fluor 700, mFluor Violet 500 SE, FITC, Alexa Fluor 647, DyLight 350, PE/Cy5.5, Biotin, DyLight 594, Janelia Fluor 549, mFluor Violet 450 SE, Janelia Fluor 646Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Sizes Available: 0.1 ml