MUC1 Antibody (SPM132) [Alexa Fluor® 647] NBP2-34737AF647 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemMUC1 Antibody (SPM132) [Alexa Fluor® 647]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberNBP2-34737AF647
Quantity0.1 ml
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,CyTOF-ready,Immunocytochemistry/ Immunofluorescence
Conjugate/TagAlexa Fluor 647
Format50mM Sodium Borate
ReactivityHuman
TargetMUC1
IsotypeIgG1 Kappa
CloneSPM132
HostMouse
ImmunogenHuman milk fat globule membranes (Uniprot: P15941)
ClonalityMonoclonal
PurityProtein A or G purified
Research AreaCancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Full Gene Namemucin 1, cell surface associated
NCBI Gene AliasesADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM

Specifications/Features

Available conjugates: Available conjugates: Alexa Fluor 647

Specificity: In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This monoclonal antibody reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

Sizes Available: 0.1 ml

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