Supplier Page from Novus Biologicals, a Bio-Techne Brand for Insulin Antibody (SPM531) [Alexa Fluor® 700]
Available conjugates: Available conjugates: mFluor Violet 610 SE, DyLight 350, Alexa Fluor 532, Alexa Fluor 647, DyLight 488, DyLight 755, Biotin, DyLight 550, PE, Alexa Fluor 594, Alexa Fluor 350, FITC, HRP, Allophycocyanin, Alexa Fluor 700, Alexa Fluor 405, DyLight 650, Janelia Fluor 646, CoraFluor 1, mFluor Violet 500 SE, DyLight 680, DyLight 405, mFluor Violet 450 SE, Alexa Fluor 488Specificity: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Sizes Available: 0.1 ml