Kappa Light Chain Antibody (HP6053) [Alexa Fluor® 405] from Novus Biologicals, a Bio-Techne Brand

Available conjugates: Available conjugates: Alexa Fluor 350, Alexa Fluor 405, Janelia Fluor 669, Alexa Fluor 647, FITC, DyLight 680, mFluor Violet 500 SE, DyLight 350, DyLight 755, PE/Cy7, Allophycocyanin/Cy7, Alexa Fluor 700, DyLight 550, PE, Janelia Fluor 549, Alexa Fluor 532, mFluor Violet 450 SE, Biotin

Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Sizes Available: 0.1 ml