Supplier Page from Novus Biologicals, a Bio-Techne Brand for CD5 Antibody (C5/473) [Alexa Fluor® 647]
Available conjugates: Available conjugates: Alexa Fluor 405, DyLight 594, Alexa Fluor 647, Alexa Fluor 700, DyLight 680, Alexa Fluor 594, DyLight 405, Janelia Fluor 549, Alexa Fluor 532, DyLight 755, Alexa Fluor 750, Janelia Fluor 646Specificity: Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.Sizes Available: 0.1 ml