IGF-I/IGF-1 Antibody (SPM406) [Alexa Fluor® 647] from Novus Biologicals, a Bio-Techne Brand

Available conjugates: Available conjugates: DyLight 680, Alexa Fluor 647, DyLight 350, HRP, DyLight 550, PerCP, DyLight 405, Janelia Fluor 549, Alexa Fluor 750, Janelia Fluor 646

Specificity: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Sizes Available: 0.1 ml