Bax Antibody (SPM336) [Alexa Fluor® 647] NBP2-34763AF647 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemBax Antibody (SPM336) [Alexa Fluor® 647]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $559.00Supplier Page View Company Product Page
Catalog NumberNBP2-34763AF647
PurityProtein A or G purified
Research AreaApoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Antibody TypePrimary Antibodies
NCBI Full Gene NameBCL2 associated X, apoptosis regulator
NCBI Gene AliasesBCL2L4
StorageStore at 4C in the dark
ReactivityHu, Mk
ClonalityMonoclonal
ApplicationsWB, FCM, ICC, IF, IHC, IHC-p
ImmunogenA synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. (Uniprot: Q07812)
HostMouse
CloneSPM336
IsotypeIgG1 Kappa
TargetBax
Format50mM Sodium Borate
Conjugate/TagAlexa Fluor 647
Quantity0.1 ml

Specifications/Features

Available conjugates: Available conjugates: Allophycocyanin, Alexa Fluor 750, Alexa Fluor 647

Specificity: Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Sizes Available: 0.1 ml

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