Supplier Page from Novus Biologicals, a Bio-Techne Brand for Insulin Antibody (SPM531) [Alexa Fluor® 405]
Available conjugates: Available conjugates: DyLight 550, mFluor Violet 500 SE, FITC, Alexa Fluor 647, DyLight 350, DyLight 680, Alexa Fluor 594, Alexa Fluor 405, DyLight 488, mFluor Violet 450 SESpecificity: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Sizes Available: 0.1 ml