Supplier Page from Novus Biologicals, a Bio-Techne Brand for alpha-Smooth Muscle Actin Antibody (SPM332) [Alexa Fluor® 488]
Available conjugates: Available conjugates: DyLight 594, PerCP, Alexa Fluor 405, mFluor Violet 450 SE, Alexa Fluor 488, Janelia Fluor 646Specificity: Actin is a major component of the cytoskeleton and is present in most cell types. This monoclonal antibody is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This monoclonal antibody does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.Sizes Available: 0.1 ml