Supplier Page from Novus Biologicals, a Bio-Techne Brand for TAG-72 Antibody (CC49) [Alexa Fluor® 488]
Available conjugates: Available conjugates: Alexa Fluor 647, FITC, Biotin, DyLight 680, DyLight 405, Janelia Fluor 549, DyLight 650, Alexa Fluor 488, Janelia Fluor 646Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.Sizes Available: 0.1 ml