Supplier Page from Novus Biologicals, a Bio-Techne Brand for Vimentin Antibody (VM452) [Alexa Fluor® 488]
Available conjugates: Available conjugates: DyLight 550, FITC, DyLight 350, HRP, Alexa Fluor 488, Allophycocyanin, Biotin, DyLight 594, DyLight 405, PerCP, Janelia Fluor 549, Alexa Fluor 532, mFluor Violet 450 SE, Alexa Fluor 750, Alexa Fluor 700Specificity: This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.Sizes Available: 0.1 ml