EGFR Antibody (GFR450) [Alexa Fluor® 488] NBP2-33068AF488 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemEGFR Antibody (GFR450) [Alexa Fluor® 488]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $559.00Supplier Page View Company Product Page
Catalog NumberNBP2-33068AF488
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Full Gene Nameepidermal growth factor receptor
NCBI Gene AliasesERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA
Research AreaCancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
PurityProtein A or G purified
ReactivityHuman (Hu)
ClonalityMonoclonal
ApplicationsFCM, ICC, IF, IHC-p, Array
ImmunogenRecombinant extracellular domain of human EGFR protein (Uniprot: P00533)
HostMouse
CloneGFR450
IsotypeIgG2a Kappa
TargetEGFR
Format50mM Sodium Borate
Conjugate/TagAlexa Fluor 488
Quantity0.1 ml

Specifications/Features

Available conjugates: Available conjugates: Alexa Fluor 488

Specificity: This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Sizes Available: 0.1 ml

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