TRAIL (C92B9) Rabbit mAb 3219S from Cell Signaling Technology

Product Specs
ItemTRAIL (C92B9) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3219S
Quantity100 µl
ApplicationsW, W-S, IP, IHC-P, IF-IC, FC-FP, FC-L
ReactivityH
TargetTrail
IsotypeIgG
HostRabbit
NCBI Gene AliasesAPO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A, TRAIL
NCBI Full Gene NameTNF superfamily member 10
CloneC92B9
Molecular Weight28-30
ClonalityMonoclonal
Research AreaApoptosis

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Synthetic essentiality of TRAIL/TNFSF10 in VHL-deficient renal cell carcinomabioRxivMay 31, 2025Xuechun Wang, Loan Duong, Yujing Qin, Rossella Parrotta, Paresh Kumar Purohit, Yihao Fang, Guoqiang Liu, Jianping He, Jiling Wen, Yan Liu, et al.hour. Cells were incubated with the following primary antibodies: TRAIL (Cell Signaling Technology, #3219), Lamp1 conjugated with Alexa Fluor647 (Santa Cruz, SC-19992), and DR5 (Biolegend, #307302) at 4 C for

(2) Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapyStem Cell Research & TherapyNovember 4, 2024Miaomiao Ye, Tingxian Liu, Liqing Miao, Huihui Ji, Zhihui Xu, Huihui Wang, Jian’an Zhang, Xueqiong Zhuselection with 10 µg/mL Blasticidin-S (Solarbio, China), and the protein expression of TRAIL (1:1000, CST, #3219) was examined by western blotting. Exo extraction and characterization To obtain hCD-MSCs and hCD-MSCsTRAIL

(3) Tumor-associated macrophage clusters linked to immunotherapy in a pan-cancer censusnpj Precision OncologyAugust 9, 2024Chen Wei, Yijie Ma, Mengyu Wang, Siyi Wang, Wenyue Yu, Shuailei Dong, Wenying Deng, Liangyu Bie, Chi Zhang, Wei Shen, et al.with primary antibodies targeting CD8a (85336, CST, 1:600), PDCD1 (ab237728, Abcam, 1:500), TNFSF10 (3219, CST, 1:3000), CXCL9 (ab290643, Abcam, 1:6000), CD68 (76437, CST, 1:5000), and PanCK (ab7753, Abcam,

(4) Rickettsia rickettsii virulence determinants RARP2 and RapL mitigate IFN- β signaling in primary human dermal microvascular endothelial cellsmBioApril 10, 2024Liam Fitzsimmons, DeAnna Bublitz, Tina Clark, Ted Hackstadt(9172), phospho-STAT1 (9167), STAT2 (72604), phospho-STAT2 (88410), RIG-1 (3743), IRF-1 (8478), TRAIL (3219), and the isotype control mouse IgG2a antibody (61656) were from Cell Signaling Technologies (Danvers,

(5) Interferon alpha promotes caspase-8 dependent ultraviolet light-mediated keratinocyte apoptosis via interferon regulatory factor 1Frontiers in ImmunologyApril 10, 2024Shannon N. Loftus, Mehrnaz Gharaee-Kermani, Bin Xu, Tyson M. Moore, Andrew Hannoudi, Mischa J. Mallbris, Benjamin Klein, Johann E. Gudjonsson, J. Michelle Kahlenbergor BSA and incubated overnight at 4°C with primary antibodies (1:1000 dilution; XAF1 #13805; TRAIL #3219; IRF-1 #8478; Phospho-MLKL (Ser358) #91689; MLKL #14993; Cell Signaling Technology) followed by HRP-conjugated

(6) TRAIL predisposes non-small cell lung cancer to ferroptosis by regulating ASK-1/JNK1 pathwayDiscover OncologyFebruary 21, 2024Xiaofang Liu, Huiqian Deng, Mi Huang, Wei Zhou, Yilin Yangrehydrated, treated with 1% citric acid buffer, blocked with 3% H2O2 and incubated with TRAIL antibody (Cat#3219, 1:800, Cell Signaling Technology, Danvers, MA,USA) overnight at 4 °C followed by secondary antibody

(7) Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly(β-amino ester)sJournal of NanobiotechnologyOctober 28, 2023Yitong Zhao, Tao Bo, Chenfei Wang, Dingjin Yao, Chaolan Pan, Weiyi Xu, Hao Zhou, Ming Li, Si Zhang1:10000), Caspase 8 (Proteintech, 13423-1-AP, 1:800), Cleaved Caspase 8 (CST, 8592 S, 1:1000), TRAIL (CST, 3219 S, 1:1000) overnight at 4℃ and 1:10000 secondary antibodies (Proteintech, SA00001-1/, SA00001-2, 1:10000)

(8) Engineered cell-based therapies in ex vivo ready-made CellDex capsules have therapeutic efficacy in solid tumorsBiomedicine & PharmacotherapyJune 1, 2023Thijs A. van Schaik, Lucia Moreno-Lama, Touraj Aligholipour Aligholipour Farzani, Mian Wang, Kok-Siong Chen, Wanlu Li, Ling Cai, Yu Shrike Zhang, Khalid ShahMillipore). The membranes were incubated with primary antibodies against mIFNβ (#97450) and TRAIL (#3219) (Cell Signaling Technology), followed by peroxidase-linked secondary antibody (#7074, Cell Signaling Technology

(9) CRISPR screens identify gene targets at breast cancer risk lociGenome biologyMarch 29, 2023Tuano NK, Beesley J, Manning M, Shi W, Perlaza-Jimenez L, Malaver-Ortega LF, Paynter JM, Black D, Civitarese A, McCue K, et al.Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (CST#4370), Phospho-SAPK/JNK (Thr183/Tyr185) (CST#4668), TRAIL (CST#3219), RIP140 (Santa Cruz#sc518071), GAPDH (Santa Cruz#sc32233), c-Myc (CST#5605), TGFBR2 (Santa Cruz#sc17792),

(10) Raw Lacquer Extract from Toxicodendron vernicifluum in Combination with ONC201 Enhances the Inhibitory Effects on Colorectal Cancer Cell ActivityThe Turkish Journal of GastroenterologyMarch 14, 2023Zhezhu Jin, Department of Colorectal Surgery, Hangzhou Red Cross Hospital, Hangzhou Zhejiang, China, Yongjun Jin, Department of Colorectal Surgery, Hangzhou Red Cross Hospital, Hangzhou Zhejiang, Chinawith PBS 3 times was then performed. Cells were then covered with primary antibodies: TRAIL (number 3219S, 1:400, CST), Bcl-2 (ab218123, 1:1000, Abcam), and Bax (ab53154, 1:500, Abcam) at 4°C until the next

(11) An enhancer variant associated with breast cancer susceptibility in Black women regulates TNFSF10 expression and antitumor immunity in triple-negative breast cancerHuman molecular geneticsJanuary 1, 2023Han YJ, Zhang J, Hardeman A, Liu M, Karginova O, Romero R, Khramtsova GF, Zheng Y, Huo D, Olopade OI.conducted western blot analyses as previously described (36), using anti-TNFSF10 (Cell Signaling, #3219, 1:300 dilution), anti-tubulin (Cell Signaling, #2128, 1:2000 dilution) and anti-β-actin (abcam, #ab8227,

(12) TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40CellsOctober 18, 2022Ibraheem K, Yhmed AMA, Nasef MM, Georgopoulos NT.(#9255), phospho-p38 (#9255), Thioredoxin-1 (#2285S), phospho-p40phox (#4311), DR5 (8074), TRAIL (#3219), FasL (#4273) and Bid (2002) (Cell Signalling Technologies, supplied by New England Biolabs, Herts,

(13) DSCAM-AS1 Long Non-Coding RNA Exerts Oncogenic Functions in Endometrial Adenocarcinoma via Activation of a Tumor-Promoting Transcriptome ProfileBiomedicinesJuly 18, 2022Treeck O, Weber F, Fritsch J, Skrzypczak M, Schüler-Toprak S, Buechler C, Ortmann O.(#9542 Cell Signaling; 1:1000), anti-cleaved Caspase-3 (#9661 Cell Signaling; 1:1000), anti-TRAIL (#3219 Cell Signaling; 1:2000), anti-DR4/TRAIL-R1 (#42533 Cell Signaling; 1:1000), anti-DR5/TRAIL-R2 (#8074

(14) Targeting sphingosine kinase 1/2 by a novel dual inhibitor SKI-349 suppresses non-small cell lung cancer cell growthCell death & diseaseJuly 12, 2022Xue Y, Jiang K, Ou L, Shen M, Yang Y, Lu J, Xu W.(Beverly, MA). Antibodies for tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL, #3219), cytochrome c (Cyto-C, #4280), cathepsin B (#31718), cathepsin D (#69854), Bax (#89477) were from Signaling

(15) Understanding of cell death induced by the constituents of Taxus yunnanensis woodScientific reportsApril 15, 2022Akao Y, Terazawa R, Sugito N, Heishima K, Morikawa K, Ito Y, Narui R, Hamaguchi R, Nobukawa T.2.0.0-rc-69/1.52p, NIH). Primary antibodies used were as follows: anti-FAS (#8023), DR5 (#8074), TRAIL (#3219), cyclin D1 (#55506), cleaved caspase-8 (#9496), PARP (#9542), FADD (#2782), and phosphate-FADD (#2781;

(16) Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and ApoptosisCancer discoveryFebruary 1, 2022Togami K, Chung SS, Madan V, Booth CAG, Kenyon CM, Cabal-Hierro L, Taylor J, Kim SS, Griffin GK, Ghandi M, et al.of Massachusetts Medical School, 1:2,000), IRF7 (#4920, 1:1,000; Cell Signaling Technology), TRAIL (#3219, 1:1,000; Cell Signaling Technology), UPF1 (#ab109363, 1:10,000; Abcam), or β-actin (A5441, 1:10,000;

(17) Silencing of Mcl-1 overcomes resistance of melanoma cells against TRAIL-armed oncolytic adenovirus by enhancement of apoptosisJournal of molecular medicine (Berlin, Germany)September 1, 2021Tolksdorf B, Zarif S, Eberle J, Hazini A, Dieringer B, Jönsson F, Kreppel F, Kurreck J, Fechner H.antibodies used were E1A (sc-58658, Santa Cruz Biotechnology, Dallas, TX, USA; diluted 1:1000), TRAIL (3219, Cell Signaling Technology, Danvers, MA, USA; diluted 1:1000), Mcl-1 (4572, Cell Signaling; diluted

(18) Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2eLifeJuly 5, 2021Jeong D, Kim HS, Kim HY, Kang MJ, Jung H, Oh Y, Kim D, Koh J, Cho SY, Jeon YK, et al.RRID:AB_331284,"Western blot (1:1000, v/v)" Antibody,TRAIL (C92B9) Rabbit mAb (C92B9),Cell signaling,Cell signaling:3219S; RRID:AB_2205818,"Western blot (1:1000, v/v)" Antibody,β-Actin (13E5) Rabbit mAb,Cell signaling,Cell signaling

(19) Secreted TRAIL gene‐modified adipose‐derived stem cells exhibited potent tumor‐suppressive effect in hepatocellular carcinoma cellsImmunity, Inflammation and DiseaseMarch 1, 2021Zhuo Liu et al.13116S; Cell Signaling Technology), Vimentin (1:1000; 5741S; Cell Signaling Technology), TRAIL (1:1000; 3219S; Cell Signaling Technology), Snail‐1 (1:500; ab53519; Abcam), Bcl‐2 (1:1000; ab182858, Abcam), Bax (1:2000;

(20) 5-Fluorouracil enhances the chemosensitivity of gastric cancer to TRAIL via inhibition of the MAPK pathwayBiochemical and Biophysical Research CommunicationsFebruary 1, 2021Hui Li, Jing Lv, Jing Guo, Shasha Wang, Shihai Liu, Yingji Ma, Zhiwei Liang, Yunyun Wang, Weiwei Qi, Wensheng Qiuagainst the following proteins were purchased from Cell Signaling Technology (Beverly, MA, USA): TRAIL (#3219), Caspase-3 (#9662), Caspase-8 (#9746), Caspase-9 (#9502), Cleaved Caspase-3 (#9661), Cleaved Caspase-8

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TRAIL (C92B9) Rabbit mAb

TRAIL (C92B9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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TRAIL (C92B9) Rabbit mAb from Cell Signaling Technology

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