Description
Product Characteristics:
Synonyms: F box gene 1, F box only protein 2, F box protein 2, F box protein only 2, F-box only protein 2, FBG 1, FBG1, Fbs 1, Fbs1, Fbs2, FBX 2, FBX2, FBX2_HUMAN, FBXO 2, FBXO2, Neural F box protein NFB42, Neural F-box protein, 42-KD, rat, homolog of, NFB 42, NFB42, OCP1, Prpl4.
Target Information: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq, Jul 2008]