Fig 1: Microwaving to 48°C combined with HSP90 and TGF-ß1 inhibitors promotes the apoptosis of VX2 cells. (A) Expression of typical proteins involved in the HSP90 and TGF-ß1/SMAD4 signalling pathway in VX2 cells after microwave ablation combined with inhibitors. (B) Corresponding statistical results of western blotting (n=3). (C) Cell staining and MTT assay of the VX2 cells after microwave ablation combined with inhibitors in the R-BMSC cells; live R-BMSC cells stained with Calcein-AM are green and dead cells are red; scale bar=100 µm. *P<0.05 vs. control group. cyto c, cytochrome c; HSP90, heat shock protein 90; M, microwave; p, PF-04929113; s, SB-525334; TGF-ß1, transforming growth factor-ß1.