CIP2A (HL1925) Antibody sc-80662 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCIP2A (HL1925) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-80662
Antibody TypePrimary Antibodies
NCBI Gene Aliasesp90, KIAA1524, NOCIVA
Quantity200 µg/ml
CloneHL1925
ApplicationsWB, IP, IF, IHC(P)
Reactivityhuman
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namecellular inhibitor of PP2A
TargetCIP2A
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) ZSCAN4 functions as a safeguard to maintain centromere integrity during oocyte meiosisGenome BiolJuly 15, 2025Da Yi Choi, Jiyeon Leem, Crystal Lee, Jeong Su Ohanti-SMC3 (1:100, ab128919, Abcam), anti-SMC4 (1:100, NBP1-86,635, Novus Biologicals), anti-CIP2A (1:500, sc-80662, Santa Cruz), and anti-p-MDC1 (1:250, ab35967, Abcam). After being washed three times, the oocytes were

(2) Novel BRCA1–PLK1–CIP2A axis orchestrates homologous recombination-mediated DNA repair to maintain chromosome integrity during oocyte meiosisNucleic Acids ResearchJanuary 11, 2025Crystal Lee, Jeong Su OhOocytes were then matured in IBMX-free M2 medium for 5 h before an injection of CIP2A (Santa Cruz, sc-80662), BRCA1 (Abcam, ab17680) or IgG (Santa Cruz, sc-2027) antibodies at a final concentration of 100 ng/μl.

(3) Celastrol impairs tumor growth by modulating the CIP2A-GSK3β-MCL-1 axis in gastric cancer cellsAgingJuly 19, 2023Wu J, Ye F, Xu T.

(4) Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibitionCell reportsJune 27, 2023Cazzoli R, Romeo F, Pallavicini I, Peri S, Romanenghi M, Pérez-Valencia JA, Hagag E, Ferrucci F, Elgendy M, Vittorio O, et al.

(5) Oocytes can repair DNA damage during meiosis via a microtubule-dependent recruitment of CIP2A-MDC1-TOPBP1 complex from spindle pole to chromosomesNucleic acids researchJune 9, 2023Leem J, Kim JS, Oh JS.NBP1-86635, Novus Biologicals), anti-centromere (1:100, 15–234, Antibodies Incorporated), anti-CIP2A (1:500, sc-80662, Santa Cruz), anti-CENP-A (1:200, 2048S, Cell Signaling), anti-HEC1 (1:250, ab3613, Abcam) anti-p-T210-PLK1

(6) (+)-Cyanidan-3-ol inhibits epidermoid squamous cell carcinoma growth via inhibiting AKT/mTOR signaling through modulating CIP2A-PP2A axisPhytomedicine : international journal of phytotherapy and phytopharmacologyJuly 1, 2022Monga J, Suthar SK, Rohila D, Joseph A, Chauhan CS, Sharma M.

(7) Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 AxisCancer cellMay 13, 2019Elgendy M, Cirò M, Hosseini A, Weiszmann J, Mazzarella L, Ferrari E, Cazzoli R, Curigliano G, DeCensi A, Bonanni B, et al.

(8) Cucurbitacin B induces inhibitory effects via the CIP2A/PP2A/C-KIT signaling axis in t(8;21) acute myeloid leukemiaJournal of pharmacological sciencesApril 1, 2019Ma W, Xiang Y, Yang R, Zhang T, Xu J, Wu Y, Liu X, Xiang K, Zhao H, Liu Y, et al.

(9) Direct activation of PP2A for the treatment of tyrosine kinase inhibitor-resistant lung adenocarcinomaJCI insightFebruary 21, 2019Tohmé R, Izadmehr S, Gandhe S, Tabaro G, Vallabhaneni S, Thomas A, Vasireddi N, Dhawan NS, Ma'ayan A, Sharma N, et al.

(10) Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung CancerMolecules (Basel, Switzerland)February 12, 2019Liu P, Xiang Y, Liu X, Zhang T, Yang R, Chen S, Xu L, Yu Q, Zhao H, Zhang L, et al.2038) (all Cell Signaling Technology, Inc., Danvers, MA, USA), anti-CIP2A (1:500 dilution; catalog no. sc-80662), anti-phospho-Akt (S473) (1:500 dilution; catalog no. sc-7985), anti-Akt (1:500 dilution; catalog no.

(11) CIP2A depletion potentiates the chemosensitivity of cisplatin by inducing increased apoptosis in bladder cancer cellsOncology reportsNovember 1, 2018Gao F, Wang X, Chen S, Xu T, Wang X, Shen Y, Dong F, Zhong S, Shen Z.membranes were incubated overnight at 4˚C with the following antibodies: CIP2A (dilution 1:500; cat. no. sc‑80662; Santa Cruz Biotechnology, Inc., Dallas, CA, USA), AKT (dilution 1:1,000; cat. no. 9272S; Cell Signaling Technology

(12) Polyphyllin I Inhibits Proliferation and Induces Apoptosis by Downregulating AML1-ETO and Suppressing C-KIT/Akt Signaling in t(8;21) Acute Myeloid LeukemiaChemistry & biodiversityNovember 1, 2018Chai Y, Si Y, Xu J, Xiang Y, Zhao H, Si Y, Zhang T, Liu Y.

(13) Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancerInternational journal of oncologySeptember 1, 2018Liu X, Sun Z, Deng J, Liu J, Ma K, Si Y, Zhang T, Feng T, Liu Y, Tan Y.(both from ProteinTech Group, Inc., Chicago, IL, USA); anti-MMP9 (1:500; sc-6840), anti‑CIP2A (1:500; sc-80662); anti-Fos-related antigen 1 (FRA-1; 1:500; sc-271657) (Santa Cruz Biotechnology, Santa Cruz, CA, USA),

(14) Cucurbitacin B induces inhibitory effects via CIP2A/PP2A/Akt pathway in glioblastoma multiformeMolecular carcinogenesisJune 1, 2018Qin S, Li J, Si Y, He Z, Zhang T, Wang D, Liu X, Guo Y, Zhang L, Li S, et al.

(15) Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2AInternational journal of oncologyMay 1, 2018Jin L, Si Y, Hong X, Liu P, Zhu B, Yu H, Zhao X, Qin S, Xiong M, Liu Y, et al.saline containing 0.5% Tween-20. The primary antibodies used were anti-CIP2A (1:500 dilution; cat. no. sc-80662), anti-phospho-Akt (S473) (1:500 dilution; catalog no. sc-7985), anti-Akt (1:500 dilution; cat. no.

(16) Increase in CIP2A expression is associated with cisplatin chemoresistance in gastric cancerCancer biomarkers : section A of Disease markersFebruary 6, 2018Ji J, Zhen W, Si Y, Ma W, Zheng L, Li C, Zhang Y, Qin S, Zhang T, Liu P, et al.

(17) CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A during meiotic maturationDevelopment (Cambridge, England)October 15, 2017Wang H, Choe MH, Lee IW, Namgoong S, Kim JS, Kim NH, Oh JS.from Sigma-Aldrich unless stated otherwise. Antibodies used in this study were anti-CIP2A (Santa Cruz, sc80662; 1:500), anti-γ-tubulin (Abcam, ab11317; Sigma-Aldrich, T3320; 1:500), anti-PCNT (Abcam, ab4448; BD

(18) Oridonin induces apoptosis and reverses drug resistance in cisplatin resistant human gastric cancer cellsOncology lettersAugust 1, 2017He Z, Xiao X, Li S, Guo Y, Huang Q, Shi X, Wang X, Liu Y.sc‑13960), anti‑cyclin D1 (1:500 dilution; catalog no. sc‑2044), anti‑CIP2A (1:500 dilution; catalog no. sc‑80662), anti‑Akt (1:500 dilution; catalog no. sc‑8312) and anti‑phosphorylated (p) Akt (Ser473; 1:500 dilution;

(19) Arctigenin inhibits triple-negative breast cancers by targeting CIP2A to reactivate protein phosphatase 2AOncology reportsJuly 1, 2017Huang Q, Qin S, Yuan X, Zhang L, Ji J, Liu X, Ma W, Zhang Y, Liu P, Sun Z, et al.cat. no. 9542) (Cell Signaling Technology, Danvers, MA, USA), anti-CIP2A (1:500 dilation; cat. no. sc‑80662), anti-phospho-Akt (Ser473) (1:500 dilation; cat. no. sc‑7985), anti-Akt (1:500 dilation; cat. no. sc‑8312), anti-CDK2

(20) Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cellsOncology reportsJuly 1, 2017Liu X, Duan C, Ji J, Zhang T, Yuan X, Zhang Y, Ma W, Yang J, Yang L, Jiang Z, et al.used were anti-MRP1 (ratio of 1:500 dilution; catalog no. sc-13960), anti-CIP2A (1:500; catalog no. sc-80662), anti-phospho-Akt (S473) (1:500; catalog no. sc-7985), anti-Akt (1:500; catalog no. sc-8312), (Santa Cruz Biotechnology

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CIP2A (HL1925) Antibody

CIP2A (HL1925) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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CIP2A (HL1925) Antibody from Santa Cruz Biotechnology, Inc.

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