SUZ12 (D39F6) XP ® Rabbit mAb 3737S from Cell Signaling Technology

Product Specs
ItemSUZ12 (D39F6) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number3737S
Quantity100 µl
ApplicationsW, IP, IF-IC, FC-FP, ChIP, ChIP-seq, C&R, eCLIP
ReactivityH, M, R, Mk
TargetSUZ12
IsotypeIgG
HostRabbit
NCBI Gene AliasesCHET9, IMMAS, JJAZ1
NCBI Full Gene NameSUZ12 polycomb repressive complex 2 subunit
CloneD39F6
Molecular Weight83
ClonalityMonoclonal
Research AreaChromatin Regulation / Nuclear Function

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Embryonic stem cell factors DPPA2/4 amplify active H3K4me3–H2AK119ub chromatin domains in non-small cell lung cancerGenes & DevelopmentMay 4, 2026Janith A. Seneviratne, Clare L. Crisp, Eleanor Glancy, Natalie Choy, Winnie Tan, Matthew Neve, Melanie Stammers, Tongtong Wang, Ruby Johnstone, Arshnoor Kaur, et al.and Abcam ab154642), 4 µg of KDM2A (Invitrogen PA5-40421), 1 µg of SUZ12 (Cell Signaling Technology 3737), 0.5 µg of H3K4me3 (Cell Signaling Technology 9751), 0.5 µg of H3K27me3 (Cell Signaling Technology

(2) UHRF1 drives subtype-independent aggressiveness and immune evasion in small cell lung cancer through PRC2 interactionsiScienceApril 17, 2026Yijun Gu, Jamie-Jean De La Torre, Yasamin Fazeli, J. Mateo Valenzuela, Frederick Guzman, Roberto Tinoco, Claudia A. BenaventeM2,Sigma-Aldrich,F1804 GATA2,Cell Signaling Technology,79802 EZH2,Cell Signaling Technology,5246 SUZ12,Cell Signaling Technology,3737 "goat anti-rabbit, HRP",Vector Laboratories,PI-1000 "horse anti-mouse, HRP",Vector Laboratories,PI-2000 "goat

(3) Xist RNA dependent and independent mechanisms regulate dynamic X chromosome inactivation in B lymphocytesCell ReportsApril 9, 2026Natalie E. Toothacre, Kiara L. Rodríguez-Acevedo, Keenan J. Wiggins, Christopher D. Scharer, Montserrat C. AngueraGenScript), Ring1b (3:50 dilution; Cat #5694, Cell Signaling Technology), or Suz12 (3:50 dilution; Cat #3737, Cell Signaling Technology) were added and beads were rotated at 4°C for 5 hr. Beads were washed with

(4) Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genesMol CellMarch 19, 2026Steven Ingersoll, Abby Trouth, J. Carlos Angel, Xinlong Luo, Axel Espinoza, Joey Wen, Chengjie Zhu, Joseph Tucker, Kalkidan Astatike, Christopher J. Phiel, et al.AB_2267885" Anti-EZH2,Millipore,"Cat# 07-689, , RRID: AB_417397" Anti-SUZ12,Cell Signaling,"Cat# 3737S, RRID: AB_2196850" Anti-OCT3/4,Santa Cruz,"Cat# sc-5279, RRID: AB_628051" Anti-NANOG,Abcam,"Cat# ab14959,

(5) Pseudouridine selects RNAs for extracellular transportbioRxivMarch 8, 2026Alessandro Scacchetti, Tuan D. Tran, Emily J. Shields, Lauren N. Reich, John F. Doherty, Julia A. Tasca, Grace E. Lee, Alejandro A. Vilcaes, Richard Lauman, Natali L. Chanaday, et al.ab19903), 1:500 for αPUS1 (Abcam, Cat. No ab203010), 1:1000 for αSUZ12 (Cell Signaling Technology, Cat. No 3737S), 1:1000 for αTUBB (Abcam, Cat. No ab6046). Export of synthetic sgRNAs sgRNAs containing uridine or

(6) EZH2 PROTACs outperform catalytic inhibitors in prostate cancer by targeting a methylation-independent function of PRC2OncogeneFebruary 18, 2026Wanqing Xie, Qi Chu, Lourdes Brea, Guihua Zeng, Yuan Wang, Xiaodong Lu, Mohan Zheng, Corinne R. Ley, Zhiquan Lei, Hongshun Shi, et al.contamination. The following antibodies were used: rabbit anti-EZH2 (5246S; CST, MA, USA); rabbit anti-SUZ12 (3737S; CST); sheep anti-EED (AF5827; R&D, MN, USA); rabbit anti-VHL (68547S; CST); rabbit anti-AR (06-680;

(7) CBFA2T2: a novel H3K27 reader regulating metabolism and tumor growthMolecular CancerFebruary 17, 2026Shengfei He, Yutian Ou, Fangfang Jiao, Jiuxing Feng, Ping Zhu, Jie Ma, Ning Xu, Haitao Li, Rui GuoAbclonal); H3 (1:6000;# ab1791,Abcam); EZH2(1:1000;# 5246,Cell Signaling Technology); SUZ12(1:1000 ;# 3737,Cell Signaling Technology); EED (1:1000;# 85322,Cell Signaling Technology); UTX (1:1000;# 33510,Cell Signaling Technology

(8) Investigating the oncogenic role of aberrant EZH2 in hepatoblastomaScientific ReportsFebruary 6, 2026Kathryn Glaser, Erica A. K. DePasquale, Lara Berklite, Brian T. Hickner, Priyanka Rao, Roma H. Patel, Andrew A. Badachhape, Somak Roy, Emily Schepers, Nikolai A. Timchenko, et al.H3K27me3 RRID:AB_2616029, 9733, 1:1,000, EED RRID: AB_2923355, 85,322, 1:200, SUZ12 RRID: AB_2196850, 3737, 1:200). CinCseq mutation panel To assess the mutational landscape of HB samples, we performed targeted

(9) A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasisbioRxivJanuary 25, 2026Neil G. Patel, Alexandra Drakaki, Farhan Valummel, Jack C. Moore, Amrita Basu, Bin Hu, Xiaolin Dong, Peng Zhao, Mees Botman, Emily Spector, et al.#39076, 1:200), TRIM28 (Cell Signaling Technology, #85322; 1:1000), SUZ12 (Cell Signaling Technology, #3737; 1:1000), EED (Cell Signaling Technology, #85322; 1:1000), H3K27me3 (Cell Signaling Technology, #9733;

(10) EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerizationNature CommunicationsJanuary 10, 2026Lihu Gong, Xiuli Liu, Xin Yang, Ze Yu, Mohd Younus Bhat, Siming Chen, Andrew Lemoff, Chao Xing, Xin Liudegradation48,49. Methods Antibodies Antibodies used in this study are listed below: SUZ12 antibody (CST, Cat. # 3737S), MTF2 antibody (Proteintech, Cat. # 162081AP), EPOP antibody (Active Motif, Cat. # 61753), JARID2 antibody

(11) Cancer-specific bivalent promoters featuring low-level H3K27me3 signals favor active transcription and govern the cancer cell state transition: Distinctive pattern of bivalency in cancerActa Biochimica et Biophysica SinicaDecember 19, 2025Fan Yang, Guanlan Fan, Jing Cao, Qiuyan Zhao, Kexiu Guo, Min Liu, Xin Yin, Hongying Zong, Feng Li, Fubing Wang, et al.anti-JARID2 (13594; Cell Signaling Technology); anti-PCL2/MTF2 (16208-1-AP; Proteintech); anti-SUZ12 (3737; Cell Signaling Technology); and anti-DYKDDDDK-Tag (M20003F; Abmart, Shanghai, China). Vectors and

(12) RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversionCell Death & DiseaseNovember 30, 2025Shiqi Lin, Dongyang Tang, Josh Haipeng Lei, Xiangpeng Chu, Lijian Wang, Kai Miao, Ping Chen, Jingbo Zhou, Aiping Zhang, Ling Li, et al.(1:1000, CST #13969), Histone 3 (1:1000, CST #9715), Ezh2 (1:1000, CST #5246), Suz12 (1:1000, CST #3737), Aebp2 (1:1000, CST #14129), β-Tubulin (1:1000, CST #2146), phosphor-Ezh2 (Thr345) (1:1000, Affinity

(13) Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2The EMBO JournalOctober 30, 2025Marlena Mucha, Zhihao Lai, Nicholas J McKenzie, Francesca Matrà, Marion Boudes, Sarena F Flanigan, Maria Teresa Alejo-Vinogradova, Craig Monger, Qi Zhang, Darragh Nimmo, et al.(2019), Antibodies,Antibodies,Antibodies AEBP2,Cell Signalling Technology,14129S SUZ12,Cell Signalling Technology,3737S EPOP,Active Motif,61753 MTF2,Proteintech,16208-1-AP GAPDH,Proteintech,60004-1 JARID2,Cell Signalling

(14) Condensation-dependent interactome of a chromatin remodeler underlies tumor suppressor activitiesNat CommunOctober 30, 2025Yasuhiro Tsukamoto, Atsuki Kawamura, Ayhan Yurtsever, Hidefumi Suzuki, Nichole Marcela Rojas-Chaverra, Hiroki Sato, Daisuke Ino, Takehiko Ichikawa, Weilin Wei, Shojiro Haji, et al.anti-ASH2L (Cell Signaling, 5019, immunofluorescence); rabbit monoclonal anti-SUZ12 (Cell Signaling, 3737, immunofluorescence); mouse monoclonal anti-SUZ12 (Santa Cruz, sc-271325, immunofluorescence, PLA);rabbit

(15) KDM4B modulates ERα signaling pathway to participate in vascular smooth muscle cell calcificationCell Death DiscovOctober 7, 2025Fei Liu, Yang Lv, Yanxia Lin, Chunyu Wang, Shengli Wang, Kai Zeng, Baosheng Zhou, Lin Lin, Jianwei Feng, Ge Sun, et al.(Proteintech, #66009-1-AP), anti-EZH2 (Proteintech, #21800-1-AP), anti-SUZ12 (Cell Signaling Technology, #3737), anti-H3K9me3 (Cell Signaling Technology, #13969) and anti-H3K27me3 (Cell Signaling Technology, #9733),

(16) Requirements for establishment and epigenetic stability of mammalian heterochromatinMolecular CellSeptember 18, 2025Antonis Tatarakis, Harleen Saini, Juntao Yu, Wenzhi Feng, Carlos A. Pinzon-Arteaga, Danesh MoazedG, 5 μg anti-G9a (Cell Signal Technology 3306S) with protein G and 5 μg anti-SUZ12 (Cell Signaling 3737S) with protein G. For histone modification ChIPs, we used 3 million cells per ChIP, while for anti-Flag,

(17) EZH2 variants derived from cryptic splice sites govern distinct epigenetic patterns during embryonic developmentNucleic Acids ResearchSeptember 9, 2025Ningning Guo, Qiuxiao Guo, Hongchao Zhan, Jian Lv, Yu Fang, Jiajie Li, Junmei Wang, Die Li, Xiao Ma, Qingqing Yan, et al.specific primary antibodies, including anti-FLAG (Sigma #F3165), anti-HA (CST, #3724), anti-SUZ12 (CST, #3737), anti-EED (CST, 51673), anti-JARID2 (CST, #13594), anti-AEBP2 (CST, #14129), anti-EZH2 (CST, #5246),

(18) Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infectionsImmunitySeptember 9, 2025Marco Di Gioia, Valentina Poli, Piao J. Tan, Roberto Spreafico, Anne Chu, Alex G. Cuenca, Zhongyang Wu, Mehdi Benamar, Laura Pandolfi, Federica Meloni, et al.,Affinity Biosciences,Cat# AF3822; RRID: AB_2847136 UZ12 (D39F6) XP® Rabbit mAb,Cell Signaling Technology,Cat# 3737; RRID: AB_2196850 "Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, HRP",Thermo Fisher Scientific

(19) Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timingNature Cell BiologySeptember 2, 2025Nan Xu, Hyein S. Cho, James O. S. Hackland, Silvia Benito-Kwiecinski, Nathalie Saurat, Oliver Harschnitz, Marco Vincenzo Russo, Ralph Garippa, Gabriele Ciceri, Lorenz Studer#14697S); rabbit anti-Menin (EpiCypher, #13-2021); rabbit anti-SUZ12 (Cell Signaling Technologies, #3737S); HRP-conjugated rabbit anti-GAPDH (Cell Signaling Technologies, #3683S). The following secondary antibodies

(20) Co-profiling of in situ RNA-protein interactions and transcriptome in single cells and tissuesNature MethodsSeptember 1, 2025Qi-Xuan Cheng, Gang Xie, Xiangyu Zhang, Jie Wang, Shuangjin Ding, Yi-Xia Wu, Ming Shi, Fei-Fei Duan, Zi-Li Wan, Jing-Jia Wei, et al.(1:40, ab92545, Abcam), anti-EED (1:80, 85322, CST), anti-EZH2 (1:80, 5246, CST), anti-SUZ12 (1:80, 3737, CST) and anti-CHTOP (1:80, Invitrogen, PA544307). The following secondary antibodies were used: rabbit

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SUZ12 (D39F6) XP ® Rabbit mAb

SUZ12 (D39F6) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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SUZ12 (D39F6) XP ® Rabbit mAb from Cell Signaling Technology

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