PKM1/2 (C5E6) Rabbit mAb 3106S from Cell Signaling Technology

Product Specs
ItemPKM1/2 (C5E6) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3106S
ClonalityMonoclonal
NCBI Full Gene Namepyruvate kinase M1/2
ApplicationsWB, IP
ReactivityHu, Ms, Rt
Research AreaMetabolism
IsotypeIgG
CloneC5E6
Molecular Weight60
NCBI Gene AliasesCTHBP, HEL-S-30, OIP3, PK3, PKM2, TCB, THBP1, p58
HostRabbit
TargetPKM1/2
Quantity100 µl

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Elevated adipose inflammation, but reduced hepatic triacylglycerol storage in diet-induced obese Plin4−/− miceJournal of Biological ChemistryFebruary 1, 2026Atanaska Ivanova Doncheva, Ryoko Higa, Prabhat Khanal, Martine Villemo Øksenvåg Ingebrigtsen, Yuchuan Li, Shrikant Kolan, Pratibha Kolan, Ales Kvasnicka, Ingunn Jermstad, Shaista Khan, et al.Pdha1 (#ABS-194, Milipore), rabbit anti-PERK (#3179, Cell Signaling Technology), rabbit anti-Pkm (#3106, Cell Signaling Technology), rabbit anti-Plin1 antibody from the Londos laboratory (60), guinea pig

(2) Immunoassay for pyruvate kinase M1/2 as an Alzheimer's biomarker in CSFOpen Life SciJuly 7, 2025Matthijs B. de Geus, Pia Kivisäkk, Bianca A. Trombetta, Betty M. Tijms, Pieter Jelle Visser, Steven E. Arnold, Becky C. Carlylemonoclonal antibodies, C103A3 (Cell Signaling Technology, #3190) and C5E6 (Cell Signaling Technology, #3106), were obtained in carrier-free solution, and stored at −20°C. These antibodies bind two different epitopes

(3) SARS-CoV-2 nucleocapsid protein interaction with YBX1 displays oncolytic properties through PKM mRNA destabilizationMolecular CancerNovember 6, 2024Xin Chen, Baohong Jiang, Yu Gu, Zhaoyang Yue, Ying Liu, Zhiwei Lei, Ge Yang, Minhua Deng, Xuelong Zhang, Zhen Luo, et al.Technology, USA, catalog number: 2368), PKM1/2 (1:500, Cell Signaling Technology, USA, catalog number: 3106), LDHA (1:1000, Cell Signaling Technology, USA, catalog number: 3582), BCL-2 (1:1000, Cell Signaling Technology

(4) MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylationNature communicationsJanuary 2, 2024Chi W, Kang N, Sheng L, Liu S, Tao L, Cao X, Liu Y, Zhu C, Zhang Y, Wu B, et al.anti-phospho-AKT (Ser473) (#4060), anti-HK1 (#2024), anti-HK2 (#2867), anti-GAPDH (#2535), anti-PKM1/2 (#3106), anti-PKM2 (#4053), anti-LDHA (#3582), anti-PDHA (#3205), anti-H3K27Ac (#8173) and anti-H3 (#4499)

(5) Warburg-associated acidification represses lactic fermentation independently of lactate, contribution from real-time NMR on cell-free systemsScientific ReportsOctober 18, 2023Zoé Daverio, Maxime Kolkman, Johan Perrier, Lexane Brunet, Nadia Bendridi, Corinne Sanglar, Marie-Agnès Berger, Baptiste Panthu, Gilles J. P. RautureauCell Signaling), pPFK-FB2 (#13064S, Cell Signaling), -aldolase A (#3188S, Cell Signaling), PKM1/2 (#3106S, Cell Signaling), -HK-1 (#2024, Cell Signaling), -HK-2 (#A0994, Cell Signaling), -HK-4 (#3782, Cell Signaling

(6) TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic ComplexNon-coding RNASeptember 15, 2022Polo-Generelo S, Torres B, Guerrero-Martínez JA, Camafeita E, Vázquez J, Reyes JC, Pintor-Toro JA.(Cat# 11217-1-AP; Proteintech, Proteintech Europe Ltd, Manchester, UK), anti-Pyruvate kinase (Cat# 3106; Cell Signaling Technology), anti-Lamin A/C (Cat# sc-376248; Santa Cruz), anti-g-Catenin (Cat# A0963;

(7) Oxidative stress induced by hydrogen peroxide promotes glycolysis by activating CaMKK/LKB1/AMPK pathway in broiler breast musclePoultry ScienceMarch 1, 2022Zuodong Chen, Tong Xing, Jiaolong Li, Lin Zhang, Yun Jiang, Feng Gaomembrane, incubated with 5% bovine serum albumin and photographed. The antibodies for HK1 (#2024S), PK (#3106S), p-AMPKαThr172 (#2535) and horseradish-peroxidase-conjugated (#7074) were purchased from Cell Signaling Technology

(8) Gynura divaricata exerts hypoglycemic effects by regulating the PI3K/AKT signaling pathway and fatty acid metabolism signaling pathwayNutrition & DiabetesDecember 1, 2020Wenjun Xu, Zhongxia Lu, Xin Wang, Man Hei Cheung, Meiai Lin, Changyu Li, Yu Dong, Chun Liang, Yitao Chenagainst glyceraldehyde 3-phosphate dehydrogenase, PI3K, p-AKT, PKM1/2, and GLUT4 (#5174, #4257 S, #4060, #3106, and #2213, respectively, at 1:1000 dilution; Cell Signaling Technology, America). The blot was then

(9) Modulation of PKM activity affects the differentiation of T_H17 cellsScience signalingOctober 27, 2020Seki SM, Posyniak K, McCloud R, Rosen DA, Fernández-Castañeda A, Beiter RM, Serbulea V, Nanziri SC, Hayes N, Spivey C, et al.Phospho-Ser465/Ser467 SMAD2 (E8F3R), STAT5 (#9363S), STAT3 (124H6), SMAD2 (D43B4), PKM1 (D30G6), PKM2 (D784), pan PKM (#3106), Lamin B1 (D4Q4Z), Actin (AC-74). All Western Blotting antibodies were purchased from Cell Signaling Technologies

(10) Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T CellsCell metabolismSeptember 1, 2020Hamaidi I, Zhang L, Kim N, Wang MH, Iclozan C, Fang B, Liu M, Koomen JM, Berglund AE, Yoder SJ, et al.from Sigma-Aldrich, acetyl-lysine (#9441, 1:50), ENO1 (#3810, 1:50), ALDOA (#8060, 1:50), PKM1/2 (#3106, 1:50), OGDH (#26865, 1:50), ACO2 (#6571, 1:50), SDHA (#11998, 1:50) and SUCLG1 (#8071, 1:50) from Cell Signaling

(11) The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcriptionNature communicationsMay 6, 2019Malik N, Yan H, Moshkovich N, Palangat M, Yang H, Sanchez V, Cai Z, Peat TJ, Jiang S, Liu C, et al.(Cell signaling, Cat:4818 S,1:1000), SUFU (Cell signaling, Cat: 2522 S, 1:1000), PKM1/2 (Cell signaling, Cat:3106 S, 1:1000), NUMBL Antibody AbVantage™ Pack (Bethyl, Cat: A310-611A, 1:1000) and Translation Initiation Complex Antibody Sampler Kit

(12) Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cellsOncotargetJune 12, 2018Rauch A, Carlstedt A, Emmerich C, Mustafa AM, Göder A, Knauer SK, Linnebacher M, Heinzel T, Krämer OH.

(13) White Matter Tract Alterations in Drug-NaÃ¯ve Parkinsonâ€™s Disease Patients With Impulse Control DisordersFrontiers in NeurologyMarch 20, 2018Mahtab Mojtahed Zadeh, Amir Ashraf-Ganjouei, Farzaneh Ghazi Sherbaf, Maryam Haghshomar, Mohammad Hadi Aarabicerebellopallidal and subthalamo-cerebellar projections in the human brain. Eur J Neurosci (2013) 38(8):3106–14. doi:10.1111/ejn.12314 Conflict of Interest Statement: The authors declare that the research was

(14) Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophagesJournal of Translational MedicineDecember 1, 2017Shamila D. Alipoor, Esmaeil Mortaz, Payam Tabarsi, Parissa Farnia, Mehdi Mirsaeidi, Johan Garssen, Masoud Movassaghi, Ian M. Adcock

(15) Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stressJournal of molecular and cellular cardiologyAugust 1, 2016Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD.

(16) Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell FateStem Cell ReportsJune 14, 2016Chih-Hong Lou et al.UPF3B (from Jens Lykke-Andersen; 1:1,000 dilution), rabbit anti-mouse SMAD2/3 (Cell Signaling, catalog #3106; 1:500 dilution), rabbit anti-mouse phospho-SMAD2/3 (Cell Signaling, cat: #3108; 1:250 dilution), and

(17) Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent traffickingOncogeneFebruary 6, 2014Y Du et al.Fund. REFERENCES 1 Sorkin A, Goh LK. Endocytosis and intracellular trafﬁcking of ErbBs. Exp Cell Res 2008; 314: 3093–3106. 2 Yarden Y, Shilo BZ. SnapShot: EGFR signaling pathway. Cell 2007; 131: 1018. 3 Lemmon MA, Schlessinger

(18) 5'-AMP Activated Protein Kinase is Involved in the Regulation of Myocardial β-Oxidative Capacity in MiceFrontiers in physiologyJanuary 1, 2012Stride N, Larsen S, Treebak JT, Hansen CN, Hey-Mogensen M, Speerschneider T, Jensen TE, Jeppesen J, Wojtaszewski JF, Richter EA, et al.malonyl-CoA-decarboxylase (MCD), (15265-1-AP, Protein Tech Group), pyruvate kinase – muscle isoform (PK), (#3106, Cell Signaling Technology), phosphorylated acetyl-CoA-carboxylase (ACCphos), (#07-303, Millipore),

(19) Maternal diets deficient in folic acid and related methyl donors modify mechanisms associated with lipid metabolism in the fetal liver of the ratBritish Journal of NutritionNovember 28, 2009Christopher J. McNeil, Susan M. Hay, Garry J. Rucklidge, Martin D. Reid, Gary J. Duncan, William D. Reesmetabolism 6411 3202 4505 3307 2716 2009 4808 4613 6702 Fat metabolism 2104 2302 3206 3501 5203 6109 Cell signalling 3106 8101 1016 3402 2004 Control 2 F, folate-deficient diet; 2F LM LC, folate-deficient diet with low methionine

(20) Enhancement of Brightness Uniformity by a New Voltage-Modulated Pixel Design for AMOLED DisplaysIEEE Electron Device LettersSeptember 1, 2006H.-Y. Lu, P.-T. Liu, T.-C. Chang, S. Chicircuit is a p-type source follower. The next stage is the V th detecting period. Only [n]EM is set 0741-3106/$20.00 © 2006 IEEE 744 IEEE ELECTRON DEVICE LETTERS, VOL. 27, NO. 9, SEPTEMBER 2006 set to high

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(1)

7/12/2019Great Antibody for PKM1/2 from CST Meng SunGreat antibody that is specific and bright.

PKM1/2 (C5E6) Rabbit mAb

PKM1/2 (C5E6) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (20)

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PKM1/2 (C5E6) Rabbit mAb from Cell Signaling Technology

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