Phospho-PDGF Receptor beta (Tyr751) (C63G6) Rabbit mAb 4549S from Cell Signaling Technology

Product Specs
ItemPhospho-PDGF Receptor beta (Tyr751) (C63G6) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number4549S
Quantity100 µl
ApplicationsW
ReactivityH, M
TargetPDGFR-b (Tyr751) phosphate
ModificationsPDGFR-b (Tyr751) phosphate
HostRabbit
NCBI Gene AliasesCD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT
ClonalityMonoclonal
NCBI Full Gene Nameplatelet derived growth factor receptor beta
IsotypeIgG
CloneC63G6
Molecular Weight190
Research AreaRTK

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Gut microbiota-derived Metabolite, Shikimic Acid, inhibits vascular smooth muscle cell proliferation and migrationBiochemical PharmacologyNovember 1, 2024Sanjana Kumariya, Arturo Grano Grano de Oro, Andrea L. Nestor-Kalinoski, Bina Joe, Islam Osman(Cell signaling Technology, Danvers, MA, cat. #: 9542, rabbit, 1:1000), pPDGFRβ (Cell signaling Technology, cat. #: 4549, rabbit, 1:1000), PDGFRβ (Cell signaling Technology, cat. #: 3169, rabbit, 1:1000), Cyclin D1 (Cell signaling Technology

(2) Hypoxia Promotes Invadosome Formation by Lung FibroblastsCellsJuly 6, 2024Mégane Lebel, Dominic O. Cliche, Martine Charbonneau, Karine Brochu-Gaudreau, Damien Adam, Emmanuelle Brochiero, Claire M. Dubois, André M. CantinLS-F16526) was from LS-bio (Lynnwood, WS, USA). Anti-PDGFRβ (cat#: 3169), anti-phosphorylated-PDGFRβ (cat#: 4549), anti-Akt (cat#: 9272), anti-phosphorylated-Akt (cat#: 9271), anti-β-actin (cat#: 4967S), and anti-rabbit

(3) Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptorsMolecular cellNovember 18, 2021Pandey S, Kumari P, Baidya M, Kise R, Cao Y, Dwivedi-Agnihotri H, Banerjee R, Li XX, Cui CS, Lee JD, et al.no. 3313, 1:1000), phospho-PKDS744/748 (CST, Cat. no. 2054, 1:1000), phospho-PDGFRY751(CST, Cat. no. 4549, 1:1000), phospho-P90RSKS380 (CST, Cat. no. 11989, 1:500). Blots were stripped with low pH stripping

(4) Efficacy of the Piperidine Nitroxide 4-MethoxyTEMPO in Ameliorating Serum Amyloid A-Mediated Vascular InflammationInternational Journal of Molecular SciencesApril 27, 2021Nathan J. Martin, Belal Chami, Abigail Vallejo, Albaraa A. Mojadadi, Paul K. Witting, Gulfam Ahmad(final dilution 1:2000 v/v; Cell-Signaling Technologies Australia) Int. J. Mol. Sci. 2021, 22, 4549 14 of 19 in 2% w/v BSA/1x TBS-T. Membranes were washed three times in 1 x TBS-T for 5 min and incubated

(5) Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesityCell stem cellApril 1, 2021Shao M, Hepler C, Zhang Q, Shan B, Vishvanath L, Henry GH, Zhao S, An YA, Wu Y, Strand DW, et al.Cell Signaling Technology, #3174 Phospho-PDGFRβ (Tyr751): 1:1000 dilution, Cell Signaling Technology, #4549 PDGFRβ: 1:1000 dilution, Cell Signaling Technology, #3169 β–TUBULIN: 1:1000 dilution, Cell Signaling Technology

(6) Polymer Capsules with Tunable Shell Thickness Synthesized via Janus-to-core shell Transition of Biphasic Droplets Produced in a Microfluidic Flow-Focusing DeviceScientific ReportsDecember 1, 2020Siyuan Xu, Takasi Nisisakojurisdictional claims in published maps and institutional affiliations. Scientific Reports | (2020) 10:4549 | https://doi.org/10.1038/s41598-020-61641-8 9 www.nature.com/scientificreports/ www.nature.com/scientificreports Open

(7) Oil Recovery Efficiency and Mechanism of Low Salinity-Enhanced Oil Recovery for Light Crude Oil with a Low Acid NumberACS OmegaJanuary 28, 2020Abhijit Kakati, Ganesh Kumar, Jitendra S. Sangwaiseawater Na+,11 806,5903,2952,295 Ca2+,1200,600,300,120 Mg2+,3960,1980,990,396 Cl–,18 197,9099,4549,1820 SO42–,2086,1043,522,20 salinity,32 754,16 378,8188,3276 pH,7.23,7.19,7.25,7.15 Ionic Composition

(8) Tau, downstream of IDH mut, inhibits the EGFR/NF-kB/TAZ mesenchymal axis, normalizing the vasculature and impairing glioma aggressivenessScience Translational MedicineJanuary 22, 2020Ricardo Gargini et al.Biotechnology OLIG2 1:100(IHC) Santa Cruz Biotechnology phospho-Ser431 AKT 1:1000 (WB) Cell Signaling (4549) phospho-Tyr751 PDGFRB 1:1000 (WB) Cell Signaling (4549) phospho-Tyr740 PDGFRB 1:100 (IHC) SIGMA

(9) 3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cellsActa pharmacologica SinicaDecember 1, 2019Shan H, Yao S, Ye Y, Yu Q.(1:3000, #9312S), p-Tyk2-Tyr1054/1055 (1:3000, #9321S), p-PDGFRα (1:2000, #4547S), p-PDGFRβ (1:2000, #4549S), p-EGFR (1:2000, #3777S), EGFR (1:2000, #4267T), p-IGF-1R (1:2000, #3024S), IGF-1R (1:2000, #3018S),

(10) Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesisNature communicationsAugust 16, 2019Han T, Jiang S, Zheng H, Yin Q, Xie M, Little MR, Yin X, Chen M, Song SJ, Beg AA, et al.(9198, 1:2000), anti-Exportin-1/CRM1 (46249, 1:1000), anti-PDGFR-β (3169, 1:1000), anti-p-Y751-PDGFR-β (4549, 1:1000), anti-Lamin B1 (13435, 1:1000) and anti-GST (2622, 1:2000) antibodies were purchased from Cell Signaling Technology

(11) The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progressionNature communicationsJuly 24, 2019Lazareth H, Henique C, Lenoir O, Puelles VG, Flamant M, Bollée G, Fligny C, Camus M, Guyonnet L, Millien C, et al.Pharmingen, 553758, 1:1000), rabbit anti-phospho-PDGF receptor-ß Y1009 (Cell Signaling Technology, 4549; 1:1000), rabbit anti-PDGFRβ (Cell Signaling, 3169; 1:1000), rabbit anti-integrin ß1 (Millipore, 04-1109,

(12) Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-ABOncogenesisMay 13, 2019Mahjour F, Dambal V, Shrestha N, Singh V, Noonan V, Kantarci A, Trackman PC.were anti-LOXL2 antibody (#GTX105085, GeneTex), rabbit mAb against phospho-PDGF Receptor β (Tyr751, #4549, Cell Signaling), rabbit mAb against phospho-PDGF Receptor β (Tyr771, #3173, Cell Signaling), rabbit

(13) Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative ProcessesJournal of dental researchOctober 1, 2018Saxena D, Mahjour F, Findlay AD, Mously EA, Kantarci A, Trackman PC.28E1), rabbit mAb (catalogue 3169), and phospho-PDGFRβ (Tyr751) (clone C63G6) rabbit mAb (catalogue 4549S). Recombinant human PDGF-BB (100-14B) was purchased from PeproTech, ECL Western blotting detection reagents

(14) LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signalingInternational journal of oncologySeptember 1, 2018Xiao Q, Dong M, Cheng F, Mao F, Zong W, Wu K, Wang H, Xie R, Wang B, Lei T, et al.rabbit monoclonal antibody 1:100 (cat. no. 3169), anti-pPDGFRβ rabbit monoclonal antibody 1:50 (cat. no. 4549), anti-pAkt rabbit monoclonal antibody 1:100 (cat. no. 4058), anti-pStat3 rabbit monoclonal antibody

(15) Effects of Sunitinib and Other Kinase Inhibitors on Cells Harboring a PDGFRB Mutation Associated with Infantile MyofibromatosisInternational journal of molecular sciencesSeptember 1, 2018Sramek M, Neradil J, Macigova P, Mudry P, Polaskova K, Slaby O, Noskova H, Sterba J, Veselska R.Signaling Technology Cell Signaling Technology A5441 4691 4060 4695 4370 9122 9121 2646 2236 3169 4549 1:20,000 1:1000 1:2000 1:1000 1:2000 1:1000 1:1000 1:1000 1:1000 1:1000 1:1000 Secondary antibodies Specificity Conjugate Manufacturer Catalog

(16) NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathyNature communicationsAugust 27, 2018Dubrac A, Künzel SE, Künzel SH, Li J, Chandran RR, Martin K, Greif DM, Adams RH, Eichmann A.Millipore), anti-α-smooth muscle actin CY3 (1/200, α-SMA, C6198, Sigma), anti-PDGFRβ 751 (1/1000, #4549, Cell Signaling), anti-PDGFRβ 1009 (1/1000, #3124, Cell Signaling), anti-PDGFRβ 1021 (1/1000, #2227,

(17) A novel AGGF1-PDGFRb fusion in pediatric T-cell acute lymphoblastic leukemiaHaematologicaFebruary 1, 2018Matthew S. Zabriskie et al.prepared as described above and immunoblotted for total PDGFRβ (CST #3169), phospho-PDGFRβY751 (CST #4549), and tubulin (CST #2148). haematologica 2018; 103:e89 CASE REPORTS was well tolerated and the

(18) Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinomaOncotargetNovember 24, 2017Barbhuiya MA, Mirando AC, Simons BW, Lemtiri-Chlieh G, Green JJ, Popel AS, Pandey NB, Tran PT.

(19) Chebulinic acid inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expressionScientific reportsSeptember 18, 2017Song IS, Jeong YJ, Park JH, Shim S, Jang SW.(Lexington, KY, USA). Lipofectamine 2000 reagent was purchased from Invitrogen. Anti-p-PDGFRβ (Cat. no. 4549) and anti-p‑Akt (Ser473; Cat. no. 4058) antibodies were obtained from Cell Signaling Technology, Inc.

(20) Free-water and free-water corrected fractional anisotropy in primary and premotor corticospinal tracts in chronic strokeHuman Brain MappingSeptember 1, 2017Derek B. Archer, Carolynn Patten, Stephen A. Coombesdifferences for FAT [t(44) 5 0.15; P 5 0.88] or FW [t(44) 5 0.45; P 5 0.66]. A standard space representation 4549 r r Archer et al. r Figure 1. Lesion conjunction. The lesion conjunction of the M1-CST (blue)

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Phospho-PDGF Receptor beta (Tyr751) (C63G6) Rabbit mAb

Phospho-PDGF Receptor beta (Tyr751) (C63G6) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-PDGF Receptor beta (Tyr751) (C63G6) Rabbit mAb from Cell Signaling Technology

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