XPC (D-10) Antibody sc-74410 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemXPC (D-10) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-74410
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), ELISA
Reactivitymouse, rat, human
FormatPurified
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
CloneH-300
Hostmouse
TargetXPC
IsotypeIgG2a
NCBI Gene AliasesXP3, p125, RAD4, XPCC
ClonalityMonoclonal
NCBI Full Gene Namexeroderma pigmentosum, complementation group C, XPC complex subunit, DNA damage recognition and repair factor

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Disrupting DDB2-DNA Interaction by Lapatinib Enhances Chemotherapy SensitivityInternational Journal of Biological SciencesSeptember 23, 2025Shih-Chao Hsu, Yu-Hao He, Yun-Ju Chen, Uyen Nguyen Phuong Le, Pei-Tong Liu, Thanh Kieu Huynh, Yi-Ling Chen, Ya-Ling Wei, Hsin-Chiao Chou, Wei-Chien Huang, et al.sc-393712, RRID: AB_2810840), EGFR (sc-03, RRID: AB_631420), p53 (sc-126, RRID: AB_628082), and XPC (sc-74410, RRID: AB_1131407) were purchased from Santa Cruz Biotechnology, Inc., (CA, USA). Triton extraction

(2) Constitutive nitric oxide synthases deficiency impairs cyclobutane pyrimidine dimer repair following solar UV exposure in cells and micePhotochemistry and PhotobiologyAugust 31, 2025Veronica Bahamondes Lorca, Yuxi Zhou, Christina Athans, Hailey Payne, Madison Wright, Zeinab Feyyaz, Lingying Tong, Dawn L. Sammons, Shiyong Wusc‐365062), β‐actin (1:1000, Santa Cruz Biotechnology, sc‐47778), XPC (1:1000, Santa Cruz Biotechnology, sc‐74410), phospho‐p53 (Ser15) (1:1000, Cell Signaling, 9284), p53 (1:1000, Santa Cruz Biotechnology, sc‐126),

(3) Transferrin receptor 1 nuclear translocation facilitates tumor progression via p53-mediated chromatin interactions and genome-wide alterationsSignal Transduct Target TherJuly 8, 2025Yaxin Hou, Guoheng Tang, Qizhi Wang, Meng Zhou, Ran Xu, Xuehui Chen, Guizhi Shi, Zhuoran Wang, Xiyun Yan, Jie Zhuang, et al.sc-126), anti-p53 antibody (CST, 2524), anti-p53 antibody (Abcam, ab26), anti-XPC antibody (Santa Cruz, sc-74410), anti-γH2AX antibody (Abcam, ab81299), anti-Ki67 antibody (CST, 9449), mouse IgG (CST, 5415), rabbit

(4) CARM1/PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activityNucleic Acids ResApril 30, 2025Hiroyuki Niida, Masahiko Ito, Kenta Iijima, Akira Motegi, Rin Ogihara, Hironobu Akiyama, Chiharu Uchida, Satoshi Sakai, Tatsuya Ohhata, Atsushi Hatano, et al.USA",12495, XPF,"Cell Signaling Technology, Danvers, MA, USA",13465, XPC,"Santa Cruz Biotechnology, Dallas, TX, USA",sc-74410, phospho Ser50 and Ser53 HBO1,,,See ref. [38] Myc (9E10),"Santa Cruz Biotechnology, Dallas, TX, USA",sc-40, ERCC1

(5) Poly-(ADP-ribose) serves as a scaffold for the methyltransferase METTL3/14 complex in the DNA damage responseNucleic Acids ResApril 12, 2025Claudia Gonzalez-Leal, Jin Cai, Bram A F J de Groot, Andreas Wegerer, Julia Preisser, Martijn S Luijsterburg, Andreas G Ladurnermouse-anti-XPA (1:1000, Thermo Fischer Scientific, MA5-13835), mouse-anti-XPC (1:1000, Santa Cruz Biotechnology, sc-74410), rabbit-anti-CSB (1:1000, Thermo Fischer Scientific, PA579218), goat-anti-GFP (1:1000, homemade, N/A),

(6) Human-Specific Organization of Proliferation and Stemness in Squamous Epithelia: A Comparative Study to Elucidate Differences in Stem Cell OrganizationInternational Journal of Molecular SciencesMarch 28, 2025Ashlee Harris, Kaylee Burnham, Ram Pradhyumnan, Arthi Jaishankar, Lari Häkkinen, Rafael E. Góngora-Rosero, Yelena Piazza, Claudia D. Andl, Thomas Andl(MECP2 1:100, clone D4F3, #3456, Cell Signaling Technology, Danvers, MA, USA) and XPC 1:100; D-10, sc-74410, Santa Cruz Biotechnology, Dallas, TX, USA) were incubated overnight at room temperature. Secondary

(7) Generation and characterization of CRISPR-Cas9-mediated XPC gene knockout in human skin cellsScientific ReportsDecember 28, 2024Ali Nasrallah, Hamid-Reza Rezvani, Farah Kobaisi, Ahmad Hammoud, Jérôme Rambert, Jos P. H. Smits, Eric Sulpice, Walid RachidiBSA, cells were incubated overnight with 1/200 primary antibodies targeting XPC (mouse, Santa Cruz, sc-74410), or vimentin (rabbit, Abcam, ab92547). Secondary mouse antibody 1/500 FITC (Invitrogen, California,

(8) Xeroderma Pigmentosum Type C Primary Skin Fibroblasts Overexpress HGF and Promote Squamous Cell Carcinoma Invasion in the Absence of Genotoxic StressCancers (Basel)September 26, 2024Sahar Al-qaraghuli, Yannick Gache, Maria Goncalves-Maia, Damien Alcor, Elodie Muzotte, Walid Mahfouf, Hamid-Reza Rezvani, Thierry Magnaldosections were then incubated overnight at 4 °C using the first primary antibody directed against XPC (sc-74410, Santa Cruz, 1/50) and then incubation with Alexa Fluor 568 (#16-237, Normal Rabbit IgG, Alexa Fluor™

(9) The m6A reader YTHDC2 regulates UVB-induced DNA Damage Repair and histone modification‡Photochemistry and PhotobiologyJuly 1, 2024Zizhao Yang, Michelle Verghese, Seungwon Yang, Palak Shah, Yu‐Ying Heanti-XPA (Santa Cruz, sc-28353, 1:1000), anti-XPB (Santa Cruz, sc-271500, 1:1000), anti-XPC (Santa Cruz, sc-74410, 1:800), anti-XPD (Proteintech, 10818–1-AP, 1:1000), anti-XPF (Santa Cruz, sc-398032, 1:500), anti-XPG

(10) Familial Melanoma Phenotype With Xeroderma Pigmentosum Group C (XP-C) Genotype - The Putative Role of MC1R Polymorphism as ModifierDermatology Practical & ConceptualJanuary 31, 2024Franciele Antonieta Bianchi Leidenz, Flavia Vasques Bittencourt, Williana Garcia Braga, Ellio Magno de Sá de Sá Araújo, Carolina Cavalieri Gomes, Vanessa de Fatima de Fatima Bernardes, Eitan Friedman, Luiz De Marcopossibility of residual protein function, we performed immunohistochemical analysis using XPC antibody (D-10: sc-74410, Santa Cruz Biotechnology) both on melanoma tissue from the proband and on normal mucosal tissue from

(11) The Biological Assessment of Shikonin and β,β-dimethylacrylshikonin Using a Cellular Myxofibrosarcoma Tumor Heterogeneity ModelInternational Journal of Molecular SciencesNovember 2, 2023Birgit Lohberger, Heike Kaltenegger, Nicole Eck, Dietmar Glänzer, Andreas Leithner, Nadine Kretschmer13050",rabbit,monoclonal,1:1000,ON 4 °C MSH3,Santa Cruz; Sc-271080,mouse,monoclonal,1:1000,ON 4 °C XPC,Santa Cruz; Sc-74410,mouse,monoclonal,1:1000,ON 4 °C pChk1,"Cell signaling; CS, 2348",rabbit,monoclonal,1:1000,ON 4 °C pCHk2,"Cell signaling

(12) NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicityToxicology and Applied PharmacologyOctober 1, 2023Zizhao Yang, Emma Wilkinson, Yan-Hong Cui, Haixia Li, Yu-Ying Heanti-XPA (Santa Cruz, sc-28353, 1:1000); anti-XPB (Santa Cruz, sc-271500, 1:1000); anti-XPC (Santa Cruz, sc-74410, 1:800); anti-XPD (Proteintech, 10818–1-AP, 1:1000); anti-DDB2 (Santa Cruz, sc-81246, 1:500); anti-XPF

(13) Fluorescence-microscopy-based assay assessing regulatory mechanisms of global genome nucleotide excision repair in cultured cellsSTAR protocolsSeptember 15, 2023Kusakabe M, Sugasawa K.anti-GFP,Bio Academia,Cat#: 60-001 Mouse monoclonal anti-XPC (D-10),Santa Cruz Biotechnology,Cat#: sc-74410; RRID: AB_1131407 Goat polyclonal anti-DDB2,R&D Systems,Cat#: AF3297; RRID: AB_2088829 Mouse monoclonal

(14) TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cellsCellular and molecular life sciences : CMLSSeptember 9, 2023Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A.anti-XPA (PA5-86265, Invitrogen; 1:1000), mouse anti-XPB (#8746, Cell Signaling; 1:1000), mouse anti-XPC (sc-74410, Santa Cruz; 1:1000), rabbit anti-XPD (#11963, Cell Signaling; 1:1000), rabbit anti-XPG (PA5-76039,

(15) Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteinsNucleic acids researchJuly 7, 2023Lindsey-Boltz LA, Yang Y, Kose C, Deger N, Eynullazada K, Kawara H, Sancar A.METHODS Reagents Antibodies used in Western analysis were purchased from Santa Cruz (Actin C-11, sc-1615; XPC D-10, sc-74410; CSB E-6, sc-398022) and Abcam (CSA ab137033). Biological resources The normal human skin fibroblast

(16) Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repairBiochimica et biophysica acta. Molecular cell researchNovember 1, 2022Koyauchi T, Niida H, Motegi A, Sakai S, Uchida C, Ohhata T, Iijima K, Yokoyama A, Suda T, Kitagawa M.

(17) Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC proteiniScienceApril 15, 2022Kusakabe M, Kakumu E, Kurihara F, Tsuchida K, Maeda T, Tada H, Kusao K, Kato A, Yasuda T, Matsuda T, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Mouse monoclonal anti-XPC (D-10),Santa Cruz Biotechnology,Cat#: sc-74410; RRID: AB_1131407 Goat polyclonal anti-DDB2,R&D Systems,Cat#: AF3297; RRID: AB_2088829 Mouse monoclonal

(18) eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damageOncogeneApril 1, 2022Ma S, Dong Z, Huang Y, Liu JY, Zhang JT.(ab109413) were from Abcam (Waltham, MA, USA). Antibodies against HuR (sc-5261), XPA (sc-28353), and XPC (sc-74410), the Protein G PLUS-Agarose, and siRNAs against eIF3a and Raptor were from Santa Cruz Biotechnology

(19) Early recruitment of PARP-dependent m(8)A RNA methylation at DNA lesions is subsequently accompanied by active DNA demethylationRNA biologyJanuary 1, 2022Legartová S, Svobodová Kovaříková A, Běhalová Suchánková J, Polášek-Sedláčková H, Bártová E.anti-γH2AX (#ab2893, Abcam, UK), anti-XRCC1 (#sc56254, Santa Cruz Biotechnology Inc., USA), anti-XPC (#sc74410, Santa Cruz Biotechnology Inc., USA), anti-BRCA1 (#sc6954, Santa Cruz Biotechnolgy Inc., USA), anti-RAD51

(20) Insulin-like Growth Factor-1 Impacts p53 Target Gene Induction in UVB-irradiated Keratinocytes and Human SkinPhotochemistry and photobiologyNovember 1, 2020Alkawar AMM, Castellanos AJ, Carpenter MA, Hutcherson RJ, Madkhali MAO, Johnson RM, Bottomley M, Kemp MG.antibodies against actin (Bethyl A300-485), pol η (Santa Cruz sc-17770 or Bethyl A301-231), XPC (Santa Cruz sc-74410), p21 (Santa Cruz sc-2646), sc-DDB2 (Cell Signaling 5416) or phospho-p53 (Ser15; Cell Signaling 8284)

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11/14/2019Time Course Effect of Chemoattractant on XPC Expression Somasundaram RaghavanThis antibody works great for western blot and signal is very strong. Highly recommended.

XPC (D-10) Antibody

XPC (D-10) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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XPC (D-10) Antibody from Santa Cruz Biotechnology, Inc.

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