YAP (63.7) Antibody sc-101199 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemYAP (63.7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $333.00Supplier Page View Company Product Page
Catalog Numbersc-101199
NCBI Gene AliasesYAP-1, YAP65, COB1, Yap, YKI, Yorkie, YAP, Yap65, YAP2, Yki
Antibody TypePrimary Antibodies
Quantity100 µg/ml
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, IHC(P), ELISA
FormatPurified
Hostmouse
Conjugate/TagUnconjugated
ClonalityMonoclonal
NCBI Full Gene Nameyes-associated protein 1, Yes1 associated transcriptional regulator
TargetYAP
IsotypeIgG2a
Clone63.7

Questions and Answers

Can this antibody be used for studying YAP localization in cancer cells?

Yes, the YAP (63.7) Antibody has been shown to effectively detect YAP localization in various cancer cell models, including pancreatic ductal adenocarcinoma cells, where it was utilized to assess the impact of statins on YAP translocation from the nucleus to the cytoplasm ().

Is this antibody suitable for immunofluorescence applications?

The YAP (63.7) Antibody has been successfully used in immunofluorescence assays, as indicated by its application in studies examining YAP's role in neuromuscular junction formation and its interactions with other proteins ().

How does this antibody perform in Western blotting?

The YAP (63.7) Antibody has been utilized in Western blotting to analyze YAP protein levels and phosphorylation status in various studies, including those investigating the role of NEK2 in esophageal squamous cell carcinoma ().

What species can this antibody react with?

The YAP (63.7) Antibody is reactive with multiple species, including human, mouse, and rat, making it versatile for studies across different model organisms ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Nanozyme-crosslinked dual-network hydrogel enables multi-stage modulation of the dysregulated repair cascade for regenerative wound healingBioactive MaterialsDecember 1, 2026Yan Gong, Feiyang Chu, Siyu Liu, Litao Jia, Wenshuai Liu, Haiyue Jiang, Xia Liu(Beyotime, China) for 10 min. Subsequently, cells were incubated with anti-YAP primary antibody (YAP [63.7], sc-101199; Santa Cruz Biotechnology, Inc., USA) diluted 1:250 in antibody diluent for 1 h at 37 °C. After PBS

(2) Hyperwrinkling of the nuclear lamina is associated with attenuated mechanosensitivity in giant nucleated cancer cellsSci AdvJuly 17, 2026Samere Abolghasemzade, Ryan Blanchard, Chance French, Christina R. Dollahon, Harrison Pham, Aidan Atkins, Richard B. Dickinson, Tanmay P. Lelerabbit anti–ɑ-tubulin (Abcam, ab18251; dilution 1:2000), and mouse anti-YAP (Santa Cruz Biotechnology, sc-101199; dilution 1:100) diluted in SuperBlock overnight at 4°C. The sample was washed with PBS thrice and incubated

(3) YAP Regulates the Nrf2 Signaling Axis to Attenuate Oxidative Stress and Neuroinflammation in Retinal Ganglion Cell DegenerationInvest Ophthalmol Vis SciJuly 10, 2026Shirui Zhou, Fumin Yang, Ke Ding, Rui Chen, Mingchang Zhang, Wei Liuprotein, mRNA processing factor (RBPMS; 1:800; 15187-7-AP; Proteintech, Rosemont, IL, USA); or YAP (1:400; sc-101199; Santa Cruz Biotechnology, Dallas, TX, USA). Following phosphate-buffered saline (PBS) washes, Alexa

(4) Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancerEuropean Journal of Medicinal ChemistryJuly 5, 2026David Smil, Yong Liu, Tao Xin, Taira Kiyota, Ahmed Aman, Julie Grouleff, Laurent Hoffer, Dhananjay C. Joshi, Mohammad R. Inanlou, Siyuan Song, et al.h (initially at 6 doses), fixed, and then immunostained using a YAP/TAZ antibody (Santa Cruz, YAP, sc-101199) with nuclei co-stained using DAPI (Sigma-Aldrich, D9542). Images were acquired on an IN Cell Analyzer 6000

(5) Hydrostatic pressure reduces the mechanosensitivity of cell migrationSci AdvJune 26, 2026Ayuba Akinpelu, Abby Weaver, Farnaz Hemmati, Ethan Coker, Farshad Amiri, Chrystalla Stylianou, Ravi S. Vaghasiya, Matthew T. Garnett, Daniel Nweze, Maria Kalli, et al.0.1% (v/v) Triton X-100, and 5% (v/v) bovine serum albumin (BSA) in PBS. Primary antibodies [anti-YAP (sc-101199, Santa Cruz, RRID:AB_1131430; 1:50), anti–pMLC2 (Ser19; 3671, Cell Signaling Technology, RRID:AB_330248;

(6) Identification of Markers on the Basis of Transcriptomic Analysis for Molecular Assignment of MedulloblastomaInternational Journal of Molecular SciencesJune 24, 2026Sergio Juárez-Méndez, Aarón Vázquez-Jiménez, Josselen Carina Ramírez-Chiquito, Vanessa Villegas-Ruíz, Ana Maria Niembro-Zuñiga, José Eduardo Farfán-Morales, Alfonso Marhx-Bracho, Edgar Krötzsch, Miguel Rodríguez-Morales, Emma Segura-Solís, et al.against β-catenin (cat. BD610154 at a 1:500 dilution; BD Bioscience, San Jose, CA, USA), YAP1 (cat. sc-101199 at a 1:300 dilution; Santa Cruz Biotechnology, Santa Cruz, CA, USA) and GAB1 1 (cat. sc-133191 at a

(7) Flow-Induced Yap/Taz Signaling Balances Endothelial and Hematopoietic Stem Cell FatesbioRxivJune 24, 2026Wade W. Sugden, Stephan George, Zachary C. LeBlanc, Morgan T. Walcheck, Eleanor Meader, Julia Goldstein, Elizabeth Molnar, Wandi Zhu, Rubul Mout, Christopher Li, et al.0.1% Triton-X-100 in PBS) for 30 mins at 4°C. Primary antibody (1:50 dilution in blocking buffer, YAP SC-101199, Santa Cruz Biotechnology) staining was carried out for overnight at 4C. Subsequently, cells were washed

(8) Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial CellsAdvanced ScienceJune 17, 2026Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, et al.(1:500, Santa Cruz Biotechnology, sc‐9989), mouse monoclonal anti‐YAP (1:500, Santa Cruz Biotechnology, sc101199), rabbit monoclonal anti‐SNAI1 (1:500, Cell Signaling Technologies, #3879S), mouse monoclonal anti‐vimentin

(9) LATS kinase activity and tumor suppressor function are regulated by a second autophosphorylation siteJournal of Biological ChemistryMay 20, 2026Ruxin Jin, Zhenxing Zhong, Rui Zhu, Anlan Zhang, Jian Li, Fa-Xing Yu, Yu WangFLAG-tagged LATS2 WT or CLS-A mutant. A mouse monoclonal anti-YAP1 antibody (Santa Cruz Biotechnology, #sc-101199, 1:100 diluted) was used to detect YAP. Immunohistochemistry Tumor tissues were fixed in general-purpose

(10) Fluid shear stress enhances pancreatic cancer motility through YAP activationClinical EpigeneticsMay 20, 2026Juan Deng, Giulia Lencioni, Aldo Pastore, Adam E. Frampton, Dongmei Deng, Elisa GiovannettiBSA for 1 h. Samples were incubated with a primary antibody against YAP (Santa Cruz Biotechnology, sc-101199) overnight at 4 °C, followed by incubation with a secondary antibody. The YAP nuclear-to-cytoplasmic

(11) Primary Cilium Forces Neuroendocrine Shift in Prostate Cancer through YAP1 Repression and Reduced Mitochondrial ActivityTheranosticsMay 18, 2026Yingbo Guo, Siyong Peng, Thibaud Jamet, Virginie Firlej, Marie Irondelle, Constance Nau, Christophe A. Girard, Kaushal Asrani, Tamara L. Lotan, Romain Huc, et al.primary and then secondary antibodies in 5% non-fat milk in TN buffer. Mouse monoclonal anti YAP1 (sc-101199) and anti ERK2 (sc-1647) antibodies were from Santa Cruz Biotechnology (Germany). Mouse monoclonal anti

(12) The Ion Channel, CFTR, assembles with HIPPO pathway proteins TAZ and YAP in polycystic kidney diseaseJournal of Biological ChemistryMay 14, 2026Abhishek Sharma, Masoud Afshani, Cristian Ciobanu, Tanvi Sharma, John T. Kress, William B. Guggino, Liudmila CebotaruMouse anti-CFTR (clone M3A7), Mouse anti-TAZ (sc-293183, Santa Cruz Biotechnology), Mouse anti-YAP (sc-101199, Santa Cruz Biotechnology) and loading controls such as Mouse anti-Vinculin (sc-59803, Santa Cruz Biotechnology)

(13) Emerin is necessary for microtubule-organizing center translocation to the nuclear envelope of muscle cellsCell Death & DiseaseMay 12, 2026Elisabetta Mattioli, Vittoria Cenni, Patrizia Sabatelli, Elisa Schena, Spartaco Santi, Chiara Fiorillo, Claudio Bruno, Antonella Pini, Melania Giannotta, Marco Cavallo, et al.MO, USA) used 1:100 for IF; anti-dynein (Ab23905, Abcam, Cambridge, UK) used 1:250 for IF; anti-YAP (sc-101199, Santa Cruz Biotechnology, Dallas, TX, USA) used 1:100 for IF; anti-TOM20 (sc-11415, Santa Cruz Biotechnology,

(14) Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control NodesAdvanced ScienceMay 1, 2026Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, et al.Immunofluorescence Immunofluorescence was performed on 4% PFA‐fixed cells using anti‐YAP/TAZ (Santa Cruz Biotechnology no. sc‐101199 1:100), anti‐vinculin (Invitrogen no. MA5‐11690 1:100), anti‐paxillin (abcam no. ab32084 1:50), anti‐α5β1

(15) Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeletonNature MaterialsApril 29, 2026Amy E. M. Beedle, Vivek Sharma, Jorge Oliver-De La Cruz, Anuja Jaganathan, Aina Albajar-Sigalés, F. Max Yavitt, Kaustav Bera, Ion Andreu, Ignasi Granero-Moya, Dobryna Zalvidea, et al.nuclei, and the samples were washed thoroughly. Primary antibodies and their dilutions YAP (1:300, sc-101199, Santa Cruz Biotechnology) or (1:300, 14074S, Cell Signaling); integrin α5, clone SNAKA51 (1:300, MABT201,

(16) Matrix Stiffness Drives Aggressive Phenotype in Tongue Squamous Cell Carcinoma via Mechanotransduction-Stromal SignallingInt Dent JApril 25, 2026Watcharaphol Tiskratok, Maythwe Kyawsoewin, Rachadol Thuephut, Kansuda Ketkrathok, Chichaya Leerahakanch, Patipan Chanwises, Paiboon Jitprasertwong, Masahiro Yamada, Hiroshi Egusa, Phoonsuk Limraksasincadherin monoclonal antibody (ab98952, diluted 1:200 in 3% BSA) or an anti-YAP monoclonal antibody (sc-101199, diluted 1:200 in 3% BSA, Santa Cruz Biotechnology). Following this step, the samples were treated with

(17) Cyclic mechanical stretch suppresses intrinsic apoptosis in high metastatic melanomaMaterials Today BioApril 22, 2026Taehoon Lee, WonJun Jang, Geonwoo Kim, Giheon Ha, Minseok Kim, Soojin Park, Geonho Lee, Hyun-Jong Cho, Yu Shrike Zhang, Han-Jun Kim, et al.acquired from SPL Life Sciences. Rabbit anti-MKL1 (A8504) was acquired from ABclonal. Mouse anti-YAP (sc-101199) and CD31/PECAM-1 antibody (H-3) (sc-376764) were acquired from Santa Cruz Biotechnology. Alexa Fluor

(18) Mechanical cues regulate in vitro implantation of mouse embryosMater Today BioApril 18, 2026Qian Liu, Kai Chen, Shaoshan Pan, Tao Zhang, Qian Wang, Jiaying Zhu, Jin Zhang, Xiaohua Jiang, Haiying Jia, Shengxia Zheng, et al.E-cadherin (1:100, 20874-1-AP, Proteintech), p-MLC (1:100, 3675T, Cell Signaling Technology), YAP (1:100, sc-101199, Santa Cruz), Vinculin (A2752, Abclonal) and CoraLite Plus 488‐conjugated Phalloidin (PF00001, Proteintech).

(19) The MST4–14-3-3ζ complex promotes pancreatic cancer by activating YAPBiology DirectApril 14, 2026Luyang Tian, Zhangting Zhao, Shisi Ding, Mingquan Li, Yi Han, Chunxiao Zhu, Yu Pan, Xiaowei Wang, Wei Kang, Liwei An, et al.(catalog no. 13008), and β-actin (catalog no. 4967 S) was from Cell Signaling Technology. Antibody to YAP (sc-101199) was from Santa Cruz Biotechnology. Goat anti-rabbit secondary antibody (catalog no. 31460) and goat

(20) ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem CellsAdvanced ScienceApril 10, 2026Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, et al.37°C. Next, the cells/tissue sections were incubated with primary antibodies Yap (1:100, Santa Cruz; sc‐101199) and p‐ERK1/2 (1:200, Cell Signaling Technology; 4376) overnight at 4°C. Subsequently, the cells/tissue

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YAP (63.7) Antibody

YAP (63.7) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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YAP (63.7) Antibody from Santa Cruz Biotechnology, Inc.

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