MHC Class II RT1Bu Antibody (OX-3) [Alexa Fluor® 647] NB100-65011AF647 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemMHC Class II RT1Bu Antibody (OX-3) [Alexa Fluor® 647]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $719.00Supplier Page View Company Product Page
Catalog NumberNB100-65011AF647
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Gene AliasesDRB1, HLA-DR1B, HLA-DRB, SS1
NCBI Full Gene Namemajor histocompatibility complex, class II, DR beta 1
Research AreaAdaptive Immunity, Asthma, B Cell Development and Differentiation Markers, Cell Biology, Diabetes Research, Immune System Diseases, Immunology, Transcription Factors and Regulators
PurityProtein A or G purified
ReactivityRat (Rt)
ClonalityMonoclonal
ApplicationsFCM, IHC, IHC-fr, IHC-p
ImmunogenRat thymocyte membrane glycoproteins
HostMouse
CloneOX-3
IsotypeIgG1
TargetMHC Class II RT1Bu
Format50mM Sodium Borate
Conjugate/TagAlexa Fluor 647
Quantity0.25 ml

Specifications/Features

Available conjugates: Available conjugates: FITC, Alexa Fluor 647

Specificity: NB100-65011 recognizes a polymorphic determinant of rat Ia antigen (RT1Bu) present on Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains (1,2). This antibody is useful for distinguishing Ia positive cells from different rat strains, e.g. for recognizing cells of donor origin in bone marrow reconstituted radiation chimaeras (3,4). MRC OX-3 cross reacts with mouse strains of MHC haplotypes b and s, and analysis of recombinant mouse strains showed that the determinants mapped to the I-A region. NB100-65011 recognizes Ia antigens on B-cells, dendritic cells and certain epithelial cells (1,3,4). This product is routinely tested in flow cytometry on Lewis rat splenocytes.

Sizes Available: 0.25 ml

Add to Compare List