MDMX (D-4) Antibody sc-74468 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMDMX (D-4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-74468
Antibody TypePrimary Antibodies
NCBI Gene AliasesBMFS6, Mdmx, 4933417N07Rik, MDMX, HDMX, MRP1
CloneD-4
Quantity200 µg/ml
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, ELISA
ClonalityMonoclonal
Hostmouse
FormatPurified
Conjugate/TagUnconjugated
NCBI Full Gene Nametransformed mouse 3T3 cell double minute 4, MDM4 regulator of p53
TargetMDMX
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosisCell Death DisAugust 23, 2023Fenyong Yao, Shisheng Huang, Jiahui Liu, Chunhua Tan, Mengqi Xu, Dengkui Wang, Maoqing Huang, Yiyao Zhu, Xingxu Huang, Shuijin He(1;1000; Abcam ab26), mouse anti-MDM2 (1:200; Santa Cruz sc-965), mouse anti-MDM4 (1:200; Santa Cruz sc-74468), and anti-β-actin (1:5000; Millipore), followed by incubation with HRP-conjugated secondary antibody.

(2) Involvement of miRNA-34a regulated Krüppel-like factor 4 expression in hyperoxia-induced senescence in lung epithelial cellsRespiratory researchDecember 10, 2022Maeda H, Yao H, Go H, Huntington KE, De Paepe ME, Dennery PA.against p53 (ab131442, Abcam), p21 (ab109199, Abcam), p16 (ab108349, Abcam), MDM4 (ab222905, Abcam or sc-74468, Santa Cruz), E2F1 (ab137415, Abcam), E2F3 (sc-56665, Santa Cruz), CCND1 (ab134175, Abcam), KLF4 (ab129473,

(3) Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitorsEuropean journal of medicinal chemistryNovember 5, 2022Espadinha M, Lopes EA, Marques V, Amaral JD, Dos Santos DJVA, Mori M, Daniele S, Piccarducci R, Zappelli E, Martini C, et al.

(4) CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiformeEuropean journal of pharmacologyApril 15, 2021Daniele S, La Pietra V, Piccarducci R, Pietrobono D, Cavallini C, D'Amore VM, Cerofolini L, Giuntini S, Russomanno P, Puxeddu M, et al.

(5) MDM4 as a Prognostic Factor for Patients With Gastric Cancer With Low Expression of p53Anticancer researchMarch 1, 2021Zhang X, Yamamoto Y, Wang X, Sato M, Imanishi M, Sugaya A, Hirose M, Endo S, Moriwaki T, Yamato K, et al.

(6) Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological ActivityJournal of medicinal chemistryOctober 12, 2017Giustiniano M, Daniele S, Pelliccia S, La Pietra V, Pietrobono D, Brancaccio D, Cosconati S, Messere A, Giuntini S, Cerofolini L, et al.

(7) β-Catenin C-terminal signals suppress p53 and are essential for artery formationNature communicationsAugust 8, 2016Riascos-Bernal DF, Chinnasamy P, Cao LL, Dunaway CM, Valenta T, Basler K, Sibinga NE.(Santa Cruz sc-6243, 1:500 dilution), anti-MDM2 (Santa Cruz sc-965, 1:200 dilution), anti-MDMX (Santa Cruz sc-74468, 1:200 dilution), anti-Lamin A/C (Santa Cruz sc-6215, 1:200 dilution) and anti-CBP (Santa Cruz sc-369,

(8) p53 protects against LPS-induced lung endothelial barrier dysfunctionAmerican journal of physiology. Lung cellular and molecular physiologyApril 15, 2015Barabutis N, Dimitropoulou C, Birmpas C, Joshi A, Thangjam G, Catravas JD.

(9) Melatonin down-regulates MDM2 gene expression and enhances p53 acetylation in MCF-7 cellsJournal of pineal researchAugust 1, 2014Proietti S, Cucina A, Dobrowolny G, D'Anselmi F, Dinicola S, Masiello MG, Pasqualato A, Palombo A, Morini V, Reiter RJ, et al.

(10) p53 is positively regulated by miR-542-3pCancer researchJune 15, 2014Wang Y, Huang JW, Castella M, Huntsman DG, Taniguchi T.RPL22 (sc-373993, Santa Cruz), RPS28 (14796-1-AP, Proteintech Group), MDM2 (04–1530, Millipore), MDM4 (sc-74468, Santa Cruz), PIRH2 (sc-166293, Santa Cruz), p21 (554228, BD Pharmigen), Bax (H00000581-M01, Abnova),

(11) Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cellsCancer scienceMarch 1, 2011Endo S, Yamato K, Hirai S, Moriwaki T, Fukuda K, Suzuki H, Abei M, Nakagawa I, Hyodo I.

(12) 14-3-3Gamma inhibition of MDMX-mediated p21 turnover independent of p53The Journal of biological chemistryFebruary 18, 2011Lee JH, Lu H.

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MDMX (D-4) Antibody

MDMX (D-4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MDMX (D-4) Antibody from Santa Cruz Biotechnology, Inc.

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