p-insulin Rβ (10C3) Antibody sc-81500 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemp-insulin Rβ (10C3) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-81500
Antibody TypePrimary Antibodies
NCBI Gene AliasesIR-B, IR-A, 4932439J01Rik, IR, CD220, HHF5, D630014A15Rik
Clone10C3
Quantity50 µg/0.5 ml
ApplicationsWB, IP
Reactivitymouse, rat, human
FormatPurified
Hostmouse
Conjugate/TagUnconjugated
ClonalityMonoclonal
NCBI Full Gene Nameinsulin receptor
IsotypeIgG1
Targetp-insulin Rβ

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Role of the Insulin Receptor in Mediating Cytosolic Delivery of Proteins by a Modified Cell-Penetrating PeptidePharmaceuticals (Basel)December 12, 2025Keito Sugai, Akiko Okudaincubated with primary monoclonal antibodies against phospho-insulin receptor β (p-IRβ; clone 10C3, sc-81500; Santa Cruz Biotechnology, Dallas, TX, USA), INSR (MAA895Hu21; Cloud-Clone Corp., Houston, TX, USA),

(2) Morpho-Functional Responsiveness of Caco-2 Enterocyte-like Monolayers to Insulin in a Pro-Inflammatory EnvironmentCellsAugust 31, 2025Aurora Mazzei, Marina Damato, Ilenia Iaia, Michele Maffia, Roberta Schiavone, Tiziano Verri, Amilcare BarcaID,Dilution,Incubation Time "Phospho-INSR (Tyr 1150/1151) (Santa Cruz from DBA, Segrate, MI, Italy)",sc81500,1:1000,"Overnight, 4 °C" "INSR (GeneTex from Prodotti Gianni, Milano, Italy)",GTX101136,1:1000,"Overnight,

(3) Exploring the Role of Oleic Acid in Muscle Cell Differentiation: Mechanisms and Implications for Myogenesis and Metabolic Regulation in C2C12 MyoblastsBiomedicinesJune 26, 2025Francesco Vari, Elisa Bisconti, Ilaria Serra, Eleonora Stanca, Marzia Friuli, Daniele Vergara, Anna Maria GiudettiCell Signaling Technology, Danvers, MA, USA), insulin receptor (IR, GTX101136 GeneTex, Irvine, CA, USA), phospho-IR (pIR, SC81500, Santa Cruz Biotechnology, Dallas, TX, USA), GLUT4 (#2213, Cell Signaling Technology, Danvers, MA, USA),

(4) Cocoa and Carob Supplementation, Alone or in Combination with Metformin, Protects against Hepatorenal Injury in Zucker Diabetic Fatty RatsNutrientsSeptember 13, 2024Esther García-Díez, María Elvira López-Oliva, Jara Pérez-Jiménez, María Ángeles Martín, Sonia Ramosanti-Bcl-x, anti-Bax, anti-SIRT-1, and anti-PEPCK antibodies were obtained from Santa Cruz (sc-711, sc-81500, sc-634, sc-526, sc-74465, and sc-32879, respectively; Qimigen, Madrid, Spain). Antiphospho-Nrf2 antibody

(5) Voluntary Wheel Running Reduces Cardiometabolic Risks in Female Offspring Exposed to Lifelong High-Fat, High-Sucrose DietMedicine & Science in Sports & ExerciseAugust 1, 2024KASSANDRA GONZALEZ, ANDREA CHIÑAS MERLIN, ERIN ROYE, BEOMSOO JU, YOUNGIL LEE, ADAM J. CHICCO, EUNHEE CHUNG(sc-56330), nitrotyrosine (sc-32757), MAO-A (sc-271123), CD36 (sc-7309), DGAT1 (sc-271934), p-IRb (sc-81500), Rb (sc-373975), dilution 1:500 (Santa Cruz Biotechnology, Santa Cruz, CA); GLUT4 (NBP1–49533), CuZnSOD

(6) Voluntary Wheel Running Reduces Cardiometabolic Risks in Female Offspring Exposed to Lifelong High-Fat, High-Sucrose DietMed Sci Sports ExercApril 6, 2024Kassandra Gonzalez, Andrea Chiñas Merlin, Erin Roye, Beomsoo Ju, Youngil Lee, Adam J. Chicco, Eunhee Chung(sc-56330), nitrotyrosine (sc-32757), MAO-A (sc-271123), CD36 (sc-7309), DGAT1 (sc-271934), p-IRb (sc-81500), Rb (sc-373975), dilution 1:500 (Santa Cruz Biotechnology, Santa Cruz, CA); GLUT4 (NBP1–49533), CuZnSOD

(7) Beta‐Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5Advanced ScienceApril 1, 2024Lu Ding, Yang Sun, Yan Liang, Jie Zhang, Zhendong Fu, Caiyue Ren, Pengfei Li, Wen Liu, Rong Xiao, Hao Wang, et al.(#4058s, CST), p‐AKT (T308) (#13038S, CST), IR (#sc57342, Santa Cruz Biotechnology), p‐IR (Tyr1150/1151) (#sc‐81500, Santa Cruz Biotechnology), Caspase 3 (#14 220, CST), Caspase 9 (#9508S, CST), Bcl‐2 (#ab182858, Abcam),

(8) Increased IGFBP2 Levels by Placenta-Derived Mesenchymal Stem Cells Enhance Glucose Metabolism in a TAA-Injured Rat Model via AMPK Signaling PathwayInternational journal of molecular sciencesNovember 20, 2023Lee DH, Park H, You JH, Seok J, Kwon DW, Kim YR, Kim GJ.1:2000, rabbit anti-INSR (PA5-27334, Invitrogen) diluted 1:2000, mouse anti-insulin receptor (phospho SC-81500, Santa Cruz) diluted 1:500, mouse anti-Nobox (SC-390016, Santa Cruz) diluted 1:1000, rabbit anti-BMP15

(9) Insulin receptor-inspired soluble insulin binderEuropean journal of cell biologyJune 1, 2023Mendoza C, Hanegan C, Sperry A, Vargas L, Case T, Bikman B, Mizrachi D.

(10) BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptidesMolecular neurodegenerationMay 4, 2023Zhou J, Singh N, Galske J, Hudobenko J, Hu X, Yan R.(D13E1),8690,AB_10999090,Cell Signaling pP38 (Thr180/Tyr182),4511,AB_2139682,Cell Signaling pIRβ (10C3),sc-81500,AB_1125642,Santa Cruz pJun(Ser63),9261,AB_2130162,Cell Signaling pErk1/2 (Thr202/Tyr204),4370,AB_2315112,Cell Signaling

(11) Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD MiceAntioxidants (Basel, Switzerland)March 15, 2023Han S, He Z, Hu X, Li X, Zheng K, Huang Y, Xiao P, Xie Q, Ni J, Liu Q.Cell Signaling Technology, Inc., Boston, MA, USA. Antibodies against IR (Cat#sc-57342), p-IR-Tyr1150 (Cat#sc-81500), and ACSL4 (Cat#sc-271800) were purchased from Santa Cruz Biotechnology, Inc., Dallas, TX, USA. The

(12) PHPB Attenuated Cognitive Impairment in Type 2 Diabetic KK-Ay Mice by Modulating SIRT1/Insulin Signaling Pathway and Inhibiting Generation of AGEsPharmaceuticals (Basel, Switzerland)February 15, 2023Li J, Xu S, Wang L, Wang X.(Cell Signaling Technology, Inc., Danvers, MA, USA), GLO1 (SC-133144) and phosphorylated-insulin RβTyr 1150/1151 (SC-81500) (Santa Cruz Biotechnology, Inc., CA, USA), β-actin (ab8224, Abcam, Cambridge, UK), and then with horseradish

(13) Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structuresNature communicationsOctober 30, 2022Kim J, Yunn NO, Park M, Kim J, Park S, Kim Y, Noh J, Ryu SH, Cho Y.MI, USA). Anti-insulin receptor β-subunit (sc-57342) antibody anti-phospho-insulin receptor (Y1150; sc-81500) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Anti-phospho-insulin receptor (Y1146;

(14) Endurance exercise-mediated metabolic reshuffle attenuates high-caloric diet-induced non-alcoholic fatty liver diseaseAnnals of hepatologyJuly 1, 2022Cook JJ, Wei M, Segovia B, Cosio-Lima L, Simpson J, Taylor S, Koh Y, Kim S, Lee Y.

(15) Metabolic regulation of (-)-epicatechin and the colonic metabolite 2,3-dihydroxybenzoic acid on the glucose uptake, lipid accumulation and insulin signalling in cardiac H9c2 cellsFood & functionMay 23, 2022García-Díez E, López-Oliva ME, Pérez-Jiménez J, Martín MA, Ramos S.

(16) Influence of Liver Cirrhosis on Blood Glucose, Insulin Sensitivity and Islet Function in MiceThe American journal of the medical sciencesOctober 1, 2021Bai XP, Fan YM, Zhang L, Yang GH, Li X.

(17) Dual Targeting of PTP1B and Aldose Reductase with Marine Drug Phosphoeleganin: A Promising Strategy for Treatment of Type 2 DiabetesMarine drugsSeptember 24, 2021Genovese M, Imperatore C, Casertano M, Aiello A, Balestri F, Piazza L, Menna M, Del Corso A, Paoli P.used were purchased by Merck (anti-insulin receptor, MABS65), Santa Cruz Biotechnology (p-insulin Rβ, sc-81500; β-actin, sc-47778), and Cell Signaling (Akt, 9272S; p-Akt, 9271S). Primary antibodies were diluted

(18) Spirulina platensis and its ingredient biopterin glucoside improved insulin sensitivity in non-alcoholic steatohepatitis modelJournal of clinical biochemistry and nutritionSeptember 1, 2021Fujihara Y, Kodo Y, Miyoshi SI, Watanabe R, Toyoda H, Mankura M, Kabuto H, Takayama F.(SREBP-1c) expressions were quantified by using the primary antibodies against these proteins respectively; sc-81500 (mouse mAb; Santa Cruz Biotechnology, Inc.), #4060S (rabbit mAb; Cell Signaling Technology, Inc., Danvers,

(19) Type I T cells sensitize treatment refractory tumors to chemotherapy through inhibition of oncogenic signaling pathwaysJournal for immunotherapy of cancerMarch 1, 2021Cecil D, Park KH, Curtis B, Corulli L, Disis MN.

(20) Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte divisioneLifeDecember 21, 2020Ow JR, Cadez MJ, Zafer G, Foo JC, Li HY, Ghosh S, Wollmann H, Cazenave-Gassiot A, Ong CB, Wenk MR, et al.Santa Cruz Biotechnology Cat#:sc-711; RRID:AB_631835 WB (1:2000) Antibody Anti-pY1151/ 1152-INSRB (Mouse monoclonal) Santa Cruz Biotechnology Cat#:sc-81500; RRID:AB_1125642 WB (1:500) Antibody Anti-LXRa (Mouse monoclonal) Abcam Cat#:ab41902; RRID:AB_776094 ChIP

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p-insulin Rβ (10C3) Antibody

p-insulin Rβ (10C3) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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p-insulin Rβ (10C3) Antibody from Santa Cruz Biotechnology, Inc.

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