EBV LMP-2A (14B7) Antibody sc-101314 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemEBV LMP-2A (14B7) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-101314
Antibody TypePrimary Antibodies
Quantity200 µg/ml
ReactivityEBV
ClonalityMonoclonal
Hostrat
Conjugate/TagUnconjugated
FormatPurified
ApplicationsWB, IF, IP
IsotypeIgG2a
TargetEBV LMP-2A
Clone14B7

Questions and Answers

Can this antibody be used to study the role of LMP2A in nasopharyngeal carcinoma?

Yes, the EBV LMP-2A (14B7) antibody has been utilized in research to investigate the role of LMP2A in promoting epithelial-to-mesenchymal transition in nasopharyngeal carcinoma cells, which is crucial for understanding tumorigenicity and cancer stem cell characteristics ().

Is this antibody effective for detecting LMP2A in different experimental setups?

The EBV LMP-2A antibody has been shown to work effectively in various applications, including Western blotting and immunofluorescence, as evidenced by its use in studies assessing LMP2A expression in model tumor cells ().

What types of cells have been studied using this antibody?

This antibody has been used in studies involving lymphoblastoid cell lines infected with Epstein-Barr virus, specifically to analyze the expression of LMP2A and its effects on cellular behavior in the context of EBV-associated malignancies (; ).

Are there any specific findings related to LMP2A that this antibody has helped uncover?

Research utilizing the EBV LMP-2A antibody has revealed that LMP2A contributes to the lytic phenotype in Type 2 EBV-infected B cells, highlighting its role in the differential gene expression and behavior of these cells compared to Type 1 EBV-infected cells ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Viral and host factors drive a type 1 Epstein–Barr virus spontaneous lytic phenotypemBioNovember 16, 2023Katherine A. Willard, Ashley P. Barry, Cliff I. Oduor, John Michael Ong'echa, Jeffrey A. Bailey, Ann M. Moormann, Micah A. Luftig,Santa Cruz,sc-81581 LMP1,S12,EBV,WB,Hybridoma,N/A EBNALP,JF186,EBV,WB,Hybridoma,N/A Magoh,21B12,Human,WB,Santa Cruz,sc-56724 Annexin V-FITC,N/A,Human,FACS,BioLegend,640906 LMP2A,14B7,EBV,WB,Santa Cruz,sc-101314 c-Myc,9E10,Human,WB,Santa Cruz,sc-40 SLAMF7/CD319-FITC,162.1,Human,FACS,BioLegend,331817 Ea-D,O261,EBV,FACS,Santa Cruz

(2) Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytesPLoS pathogensOctober 1, 2022Singh DR, Nelson SE, Pawelski AS, Cantres-Velez JA, Kansra AS, Pauly NP, Bristol JA, Hayes M, Ohashi M, Casco A, et al.1:500), anti-BMRF1 (Millipore, catalog # MAB8186, dilution 1: 2500), anti LMP2A (Santa Cruz, catalog #sc-101314, dilution 1:500), anti-EBNA1 (Santa Cruz, Catalog #sc-57719, dilution 1:500), anti-EBNA2 (Abcam, catalog

(3) Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cellsPLoS pathogensApril 1, 2022Bristol JA, Brand J, Ohashi M, Eichelberg MR, Casco A, Nelson SE, Hayes M, Romero-Masters JC, Baiu DC, Gumperz JE, et al.(Sigma #T5168), anti-actin (Sigma #A5441), anti-V5 (Santa Cruz #sc—58052), and anti LMP2A (Santa Cruz #sc-101314). The secondary antibodies used were Horseradish peroxide (HRP)- labeled goat anti-mouse antibody (Fisher Scientific

(4) EBV latent membrane proteins promote hybrid epithelial-mesenchymal and extreme mesenchymal states of nasopharyngeal carcinoma cells for tumorigenicityPLoS pathogensAugust 1, 2021Zhu N, Xu X, Wang Y, Zeng MS, Yuan Y.Abcam (Cat #ab78113). Antibody against EBV LMP2A was purchased from Santa Cruz Biotechnology (Cat #sc-101314). CD44 PE (Cat #12-0441-81), CD104 (Cat #PA5-79541), CD104 eFluor 660 (Cat #50-1049-82) antibodies were

(5) EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized micePLoS pathogensJune 1, 2020Li C, Romero-Masters JC, Huebner S, Ohashi M, Hayes M, Bristol JA, Nelson SE, Eichelberg MR, Van Sciver N, Ranheim EA, et al.Inc. ab-7502 IHC IHC&WB LMP1 Novus NBP1-79009 IHC LMP1 Abcam Inc. ab-78113 WB LMP2A Santa Cruz Biotechnology sc-101314 WB LMP2A Santa Cruz Biotechnology sc-101315 IHC BZLF1 Santa Cruz Biotechnology sc-53904 IHC&WB BZLF1 Santa Cruz Biotechnology

(6) F factor plasmid-mediated Epstein-Barr virus genome introduction establishes an EBV positive NPC cell modelCancer management and researchJanuary 1, 2019Duan J, Yang Y, Wu Z, Lin S, Zhou C, Sheng G, Yang F, Bian L, Zhang X, Xiao S.used in Western blot Antibody Primary antibody Species Dilution β-actin ZSGB-BIO (TA-09) Mouse 1:2000 LMP2A Santa Cruz (sc-101314) Rat 1:100 EBNA1 LMP1 Santa Cruz (sc-81581) Abcam (ab78113) Mouse Mouse 1:500 1:500 STAT3 Santa Cruz

(7) Constructing TC-1-GLUC-LMP2 Model Tumor Cells to Evaluate the Anti-Tumor Effects of LMP2-Related VaccinesVirusesMarch 23, 2018Sun L, Hao Y, Wang Z, Zeng Y.Membranes were incubated with EBV LMP2 monoclonal antibody (Santa Cruz Biotechnology, Dallas, TX, USA, #sc-101314) diluted 1:500 in 5% skimmed milk, and a horseradish peroxidase-conjugated goat anti-rat IgG (ZSGB-BIO,

(8) Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathwayExperimental and therapeutic medicineApril 1, 2017Kim D, Ko HS, Park GB, Hur DY, Kim YS, Yang JW.(EBNA) 2 (no. sc-17501; 1:100), EBNA3A (no. sc-23533; 1:100), latent membrane protein (LMP) 2A (no. sc-101314; 1:100), VEGFR2 (no. sc-6251; 1:500), ADAM10 (no. sc-25578; 1:500), ADAM12 (no. sc-25579; 1:500), ADAM17

(9) Epstein-Barr virus-encoded Bcl-2 homologue functions as a survival factor in Wp-restricted Burkitt lymphoma cell line P3HR-1Journal of virologyMarch 1, 2010Watanabe A, Maruo S, Ito T, Ito M, Katsumura KR, Takada K.

(10) Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factorsProceedings of the National Academy of Sciences of the United States of AmericaApril 10, 2001Higuchi M, Izumi KM, Kieff E.

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EBV LMP-2A (14B7) Antibody

EBV LMP-2A (14B7) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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EBV LMP-2A (14B7) Antibody from Santa Cruz Biotechnology, Inc.

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