DDB2 (2246C4a) Antibody sc-81246 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDDB2 (2246C4a) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $333.00Supplier Page View Company Product Page
Catalog Numbersc-81246
Quantity100 µg/ml
Reactivityhuman
ApplicationsWB, IP, IF, FCM
FormatPurified
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
Clone2246C4a
Hostmouse
TargetDDB2
IsotypeIgG1
NCBI Gene AliasesDDBB, UV-DDB2, XPE
ClonalityMonoclonal
NCBI Full Gene Namedamage specific DNA binding protein 2

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Targeting the m 6 A RNA demethylase FTO enhances UVB ‐induced DNA damage repair and suppresses skin tumor growthPhotochemistry and PhotobiologyDecember 8, 2025Zizhao Yang, Michelle Verghese, Yan‐Hong Cui, Jiangbo Wei, Seungwon Yang, Chuan He, Yu‐Ying Heimmunoblot analysis. The antibodies utilized in this study were as follows: anti-DDB2 (Santa Cruz; sc-81246; diluted at 1:500), anti-FTO (Santa Cruz; SC-271713; diluted at 1:200), anti-GAPDH (Santa Cruz; sc-47724;

(2) The m6A reader YTHDC2 regulates UVB-induced DNA Damage Repair and histone modification‡Photochemistry and PhotobiologyJuly 1, 2024Zizhao Yang, Michelle Verghese, Seungwon Yang, Palak Shah, Yu‐Ying Heantibodies used were as follows: anti-YTHDC2 (Proteintech, 27779–1-AP, 1:4000), anti-DDB2 (Santa Cruz, sc-81246, 1:500), anti-XPA (Santa Cruz, sc-28353, 1:1000), anti-XPB (Santa Cruz, sc-271500, 1:1000), anti-XPC

(3) NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicityToxicology and Applied PharmacologyOctober 1, 2023Zizhao Yang, Emma Wilkinson, Yan-Hong Cui, Haixia Li, Yu-Ying Heanti-XPC (Santa Cruz, sc-74410, 1:800); anti-XPD (Proteintech, 10818–1-AP, 1:1000); anti-DDB2 (Santa Cruz, sc-81246, 1:500); anti-XPF (Santa Cruz, sc-398032, 1:500); anti-XPG (Proteintech, 11331–1-AP, 1:800); anti-GAPDH

(4) Chromatin-remodeling factor BAZ1A/ACF1 targets UV damage sites in an MLL1-dependent manner to facilitate nucleotide excision repairBiochimica et biophysica acta. Molecular cell researchNovember 1, 2022Koyauchi T, Niida H, Motegi A, Sakai S, Uchida C, Ohhata T, Iijima K, Yokoyama A, Suda T, Kitagawa M.

(5) TRABID targets DDB2 for deubiquitination to promote proliferation of hepatocellular carcinoma cellsBiochemical and biophysical research communicationsOctober 15, 2022Chen Y, Zhang X.

(6) Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA FormationJournal of virologyJanuary 26, 2022Marchetti AL, Zhang H, Kim ES, Yu X, Jang S, Wang M, Guo H.

(7) ERα determines the chemo-resistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressionsMolecular therapy. Nucleic acidsSeptember 3, 2021He YH, Yeh MH, Chen HF, Wang TS, Wong RH, Wei YL, Huynh TK, Hu DW, Cheng FJ, Chen JY, et al.sc-393712, RRID: AB_2810840), ERα (sc-8002, RRID: AB_627558), p53 (sc-126, RRID: AB_628082), and DDB2 (sc-81246, RRID: AB_2261381) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). The antibody

(8) HDAC3 Is Required for XPC Recruitment and Nucleotide Excision Repair of DNA Damage Induced by UV IrradiationMolecular cancer research : MCRSeptember 1, 2020Nishimoto K, Niida H, Uchida C, Ohhata T, Kitagawa K, Motegi A, Suda T, Kitagawa M.

(9) CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligasesCell death and differentiationMarch 1, 2020Füzesi-Levi MG, Fainer I, Ivanov Enchev R, Ben-Nissan G, Levin Y, Kupervaser M, Friedlander G, Salame TM, Nevo R, Peter M, et al.fraction was suspended in 250 μl TBS and rotated overnight at 4 °C with 5 μl of anti-DDB2 (Santa Cruz sc81246). Then 30 μl of TBS equilibrated Protein G Sepharose resin (GE) was added for 1 h, and after three washes

(10) Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting ComplexCurrent biology : CBAugust 20, 2018Minamino M, Tei S, Negishi L, Kanemaki MT, Yoshimura A, Sutani T, Bando M, Shirahige K.

(11) Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repairNature communicationsJuly 18, 2017Niida H, Matsunuma R, Horiguchi R, Uchida C, Nakazawa Y, Motegi A, Nishimoto K, Sakai S, Ohhata T, Kitagawa K, et al.anti-HA antibody (sc-57592, Santa Cruz), anti-HBO1 antibody (sc-13284, Santa Cruz), anti-DDB2 antibody (sc-81246, Santa Cruz), anti-XPC antibody (sc-30156, Santa Cruz), anti-TFIIH p89 antibody (sc-293, Santa Cruz),

(12) UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell ProliferationMolecular and cellular biologyFebruary 1, 2016Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, Shiotani B, Matsumoto M, Nakayama KI, Ogura H, et al.anti-CUL2 antibody (sc-166506; Santa Cruz), anti-CUL4 antibody (sc-8557; Santa Cruz), anti-DDB2 antibody (sc-81246; Santa Cruz), anti␤-actin antibody (sc-47778; Santa Cruz Biotechnology), anti-ATM antibody (sc-23921;

(13) The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stabilityCell cycle (Georgetown, Tex.)December 1, 2012Zhang L, Lubin A, Chen H, Sun Z, Gong F.sources: USP24 (1:1,000, Novus, Cat No: NB100–40830), DDB2 (1:500, Santa Cruz biotechnology, Cat No: sc-81246). Micropore UV irradiation and immunofluorescence staining were performed as described previously.47

(14) TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cellsCellular and molecular life sciences : CMLSJanuary 1, 0001Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A.(#13465, Cell Signaling; 1:1000), rabbit anti-DDB1 (#5428, Cell Signaling; 1:1000), mouse anti-DDB2 (sc-81246, Santa Cruz; 1:1000). Mouse anti-β-actin (A5441, Sigma, 1:10000) protein levels were assessed by re-probing

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DDB2 (2246C4a) Antibody

DDB2 (2246C4a) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

Citations (14)

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DDB2 (2246C4a) Antibody from Santa Cruz Biotechnology, Inc.

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