Chk2 (DCS-270) Antibody sc-56296 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemChk2 (DCS-270) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-56296
Antibody TypePrimary Antibodies
NCBI Gene AliasesCDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
CloneDCS-270
Quantity200 µg/ml
Reactivityhuman
ApplicationsWB, IP, IF, IHC(P)
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
ClonalityMonoclonal
NCBI Full Gene Namecheckpoint kinase 2
TargetChk2
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinomaNAR CancerJune 13, 2023Jan Benada, Daria Bulanova, Violette Azzoni, Valdemaras Petrosius, Saba Ghazanfar, Krister Wennerberg, Claus Storgaard Sørensenphospho-CDK substrate motif 1:1000, Cell Signaling Technology, cat#9477; CHK2 1:500, Santa Cruz, cat#sc-56296; CHK2pT18 1:500, Cell Signaling Technology, cat#2661; CHK1 1:500, Santa Cruz, cat#sc-56291; CHK2pS345

(2) Kv10.1 Regulates Microtubule Dynamics during MitosisCancersAugust 25, 2020Movsisyan N, Pardo LA.,Santa Cruz Biotechnology p-CHK2 (Thr68)(C13C1),Rb/mcl,1:1000,2197,Cell Signaling CHK2 (DCS-270),Ms/mcl,1:1000,sc-56296,Santa Cruz Biotechnology p21 Waf1/Cip1,Ms/mcl,1:1000,05-345,Merck Millipore p-histone H2AX (Ser139),Rb/mcl,1:1000,sc-101696,Cell

(3) Mahanine induces apoptosis, cell cycle arrest, inhibition of cell migration, invasion and PI3K/AKT/mTOR signalling pathway in glioma cells and inhibits tumor growth in vivoChemico-biological interactionsFebruary 1, 2019Chen M, Yin X, Lu C, Chen X, Ba H, Cai J, Sun J.

(4) The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In VitroMedical science monitor : international medical journal of experimental and clinical researchJuly 16, 2018Zhang SL, Li BL, Li W, Lu M, Ni LY, Ma HL, Meng QG.

(5) Daidzein exerts anticancer activity towards SKOV3 human ovarian cancer cells by inducing apoptosis and cell cycle arrest, and inhibiting the Raf/MEK/ERK cascadeInternational journal of molecular medicineJune 1, 2018Hua F, Li CH, Chen XG, Liu XP.

(6) ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 functionEMBO reportsMay 1, 2016Ahlskog JK, Larsen BD, Achanta K, Sørensen CS.(1:10,000; DCS-310; described by [41], phospho-CHK2-T68 (1:500; 2661, Cell Signaling), CHK2 (1:500; sc56296, Santa Cruz), FBH1 (FBXO18 1:100; sc81563, Santa Cruz), GST (1:2,000; sc138, Santa Cruz), GFP (1:1,000; 1181446000,

(7) FBH1 Catalyzes Regression of Stalled Replication ForksCell reportsMarch 17, 2015Fugger K, Mistrik M, Neelsen KJ, Yao Q, Zellweger R, Kousholt AN, Haahr P, Chu WK, Bartek J, Lopes M, et al.

(8) A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientationCell cycle (Georgetown, Tex.)January 1, 2015Stolz A, Ertych N, Bastians H.

(9) Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cellsNature cell biologyAugust 1, 2014Ertych N, Stolz A, Stenzinger A, Weichert W, Kaulfuß S, Burfeind P, Aigner A, Wordeman L, Bastians H.

(10) Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cellsFood and chemical toxicology : an international journal published for the British Industrial Biological Research AssociationJune 1, 2014Bo S, Hui H, Li W, Hui L, Hong X, Lin D, Dai WX, Wu YH, Ai XH, Hao J, et al.

(11) FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stressNature communicationsJanuary 1, 2013Fugger K, Chu WK, Haahr P, Kousholt AN, Beck H, Payne MJ, Hanada K, Hickson ID, Sørensen CS.

(12) The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cellsNature cell biologyMay 1, 2010Stolz A, Ertych N, Kienitz A, Vogel C, Schneider V, Fritz B, Jacob R, Dittmar G, Weichert W, Petersen I, et al.

(13) Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathwayExperimental cell researchJanuary 15, 2005Agner J, Falck J, Lukas J, Bartek J.

(14) SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replicationNature communicationsJanuary 1, 0001"Walter D, Hoffmann S, Komseli ES, Rappsilber J, Gorgoulis V, Sørensen CS."

(15) CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiationThe Journal of cell biologyJanuary 1, 0001"Kousholt AN, Fugger K, Hoffmann S, Larsen BD, Menzel T, Sartori AA, Sørensen CS."phospho–RPA32 S4/8 (#A300-245). Antibodies from Santa Cruz Biotechnology, Inc. were CDC25A (#F-6), CHK2 (#sc-56296), 53BP1 (#sc-22760), and GFP (#sc-8334). Antibodies from Abcam were TopBP1 (#2402) and DNA2 (ab96488).

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Chk2 (DCS-270) Antibody

Chk2 (DCS-270) Antibody from Santa Cruz Biotechnology, Inc.

Description

Santa Cruz Biotechnology, Inc.

Citations (15)

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Chk2 (DCS-270) Antibody from Santa Cruz Biotechnology, Inc.

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