Cdk4 (DCS-31) Antibody sc-56277 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCdk4 (DCS-31) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-56277
Quantity200 µg/ml
ApplicationsWB, IP, IF, ELISA
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
FormatPurified
Antibody TypePrimary Antibodies
CloneDCS-31
Hostmouse
TargetCdk4
IsotypeIgG2a
NCBI Gene AliasesPSK-J3, CMM3, Crk3
ClonalityMonoclonal
NCBI Full Gene Namecyclin dependent kinase 4

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Engineering Immortalized Bovine Granulosa Cells Using a Triple‐Gene Approach: Mutant CDK4, Cyclin D1, and TERTCell Biology InternationalFebruary 1, 2026Lanlan Bai, Minami Takahashi, Jin Kobayashi, Takahiro Eitsuka, Himari Matsusaka, Taku Ozaki, Eriko Sugano, Hiroshi Tomita, Yuan Xu, Kazuhiro Kawamura, et al.detected using specific primary antibodies: anti‐CDK4 (mouse monoclonal, Santa Cruz Biotechnology, sc‐56277, 1:2000), anti‐cyclin D1 (rabbit monoclonal, Medical & Biological Laboratories, code no. 553, 1:5000),

(2) The dual HDAC/PI3K inhibitor CUDC-907 inhibits the growth and proliferation of MYC-driven Group 3 medulloblastomaCell Death DiscovApril 14, 2025Pan Gou, Chencheng Fang, Man Xu, Dandan Zhang, Xuanxuan Wu, Li Zhang, Xiao Li, Man Li, Lu Gan, Jinjin Luo, et al.γ-H2AX (#9718 T) antibodies were purchased from Cell Signaling Technology (Beverly, MA, USA). CDK4 (#sc-56277) and CDK6 (#sc-53638) antibodies were purchased from Santa Cruz (Dallas, TX, USA). The cyclin D1 (#A19038),

(3) Targeting N-Myc in neuroblastoma with selective Aurora kinase A degradersCell chemical biologyFebruary 20, 2025Tang J, Moorthy R, Hirsch LE, Demir Ö, Baker ZD, Naumann JA, Jones KFM, Grillo MJ, Haefner ES, Shi K, et al.4718 AURKB/AIM1 1:1000,Cell signaling technology,Cat# 3094 CDK4 (DCS-31) 1:1000,Santa Cruz Biotechnology,Cat# sc-56277 CDK6 (DCS83) 1:500,Cell signaling technology,Cat# 3136 CDK9 (D-7) 1:2000,Santa Cruz Biotechnology,Cat#

(4) Cleft Palate Induced by Mycophenolate Mofetil Is Associated with miR-4680-3p and let-7c-5p in Human Palate CellsNoncoding RNAFebruary 6, 2025Hiroki Yoshioka, Hanane Horita, Yosuke Tsukiboshi, Hisaka Kurita, Aya Ogata, Kenichi Ogata,Santa Cruz Biotechnology,sc-377100,1:1000 CDK2,Santa Cruz Biotechnology,sc-6248,1:1000 CDK4,Santa Cruz Biotechnology,sc-56277,1:1000 CDK6,Santa Cruz Biotechnology,sc-53638,1:500 BACH1,Santa Cruz Biotechnology,sc-271211,1:500 PAX3,Santa Cruz Biotechnology

(5) The Multi-targeted Effect of Fascaplysin on the Proliferation and Dedifferentiation of Schwann Cells Inhibits Peripheral Nerve Degeneration by Blocking CDK4/6 and Androgen ReceptorExp NeurobiolDecember 31, 2024Hyung-Joo Chung, Ja-Eun Kim, Youngbuhm Huh, Jin San Lee, So-Woon Kim, Kiyong Na, Jiwon Kim, Seung Hyeun Lee, Hiroyuki Konishi, Seung Geun Yeo, et al.was performed as previously described [5]. Primary antibodies, anti-cyclin dependent kinase 4 (CDK4, #sc-56277, Santa Cruz Biotechnology), anti-cyclin D1 (CCND1, #ma5-1451, Invitrogen), anti-NF (#n2787, Sigma-Aldrich),

(6) Establishment of immortalized Egyptian Rousettus bat cell linesFEBS Open BioApril 1, 2024Lanlan Bai, Tetsuya Tani, Takeshi Kobayashi, Ryotaro Nouda, Yuta Kanai, Yusuke Sano, Kazutoshi Takami, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, et al.antibodies were used: mouse anti‐CDK4 monoclonal (Santa Cruz Biotechnology, Dallas, TX, USA; code no. sc‐56277, 1 : 2000 dilution), rabbit anti‐cyclin D1 monoclonal (Medical & Biological Laboratories Co., Ltd.,

(7) Cationic nanoplastic causes mitochondrial dysfunction in neural progenitor cells and impairs hippocampal neurogenesisFree radical biology & medicineNovember 1, 2023Yang S, Lee S, Lee Y, Cho JH, Kim SH, Ha ES, Jung YS, Chung HY, Kim MS, Kim HS, et al.

(8) Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/ CDKN2ASignal Transduction and Targeted TherapyOctober 25, 2023Javier Martin-Broto, Jeronimo Martinez-Garcia, David S. Moura, Andres Redondo, Antonio Gutierrez, Antonio Lopez-Pousa, Javier Martinez-Trufero, Isabel Sevilla, Roberto Diaz-Beveridge, Maria Pilar Solis-Hernandez, et al.with immunohistochemistry staining. Immunohistochemistry used an anti-CDK4 mouse monoclonal antibody (sc-56277; Santa Cruz Biotechnology, Inc., Dallas, TX, USA), an anti-cyclin E mouse monoclonal antibody (sc-247;

(9) Sheep-derived cell immortalization through the expression of cell cycle regulators and biological characterization using transcriptomesCell biology internationalSeptember 1, 2023Kikuchi N, Matsusaka H, Bai L, Sano H, Eitsuka T, Nakagawa K, Sugano E, Ozaki T, Tomita H, Kiyono T, et al.

(10) The Protective Role of Glutathione against Doxorubicin-Induced Cardiotoxicity in Human Cardiac Progenitor CellsInternational journal of molecular sciencesJuly 28, 2023Lee EJ, Jang WB, Choi J, Lim HJ, Park S, Rethineswaran VK, Ha JS, Yun J, Hong YJ, Choi YJ, et al.for Cyclin D1 (1:200, Santa Cruz Biotechnology, Dallas, TX, USA; SC-8396), CDK4 (1:200, Santa Cruz, SC-56277), ERK (1:1000, Cell Signaling, 4695S), pERK (1:1000, Cell Signaling, 4376S), AKT (1:1000, Cell Signaling,

(11) Mono-(2-ethylhexyl) Phthalate (MEHP)-Induced Telomere Structure and Function Disorder Mediates Cell Cycle Dysregulation and Apoptosis via c-Myc and Its Upstream Transcription Factors in a Mouse Spermatogonia-Derived (GC-1) Cell LineToxicsMay 10, 2023Zhou F, Guo C, Wang L, Zhang G, Wang J, Chen W, Cui K, Tan Y, Zhou Z.Aldrich (Saint Louis, MO, USA, CAS: 4376-20-9, 97% pure). Commercially available antibodies against CDK4 (sc-56277) and CYCLIN D1 (sc-8396) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). The c-Myc

(12) MiR‑221 and miR‑222 regulate cell cycle progression and affect chemosensitivity in breast cancer by targeting ANXA3Experimental and therapeutic medicineMarch 1, 2023Kim JY, Jung EJ, Kim JM, Son Y, Lee HS, Kwag SJ, Park JH, Cho JK, Kim HG, Park T, et al.sc-20044; Santa Cruz Biotechnology, Inc.); anti-CDK4 (1:500; Santa Cruz Biotechnology, Inc.; cat. no. sc-56277); anti-cyclin B1 (1:500; cat. no. sc-245; Santa Cruz Biotechnology, Inc.); anti-cyclin A (1:500; cat.

(13) PP2A-B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle-related genesThe FEBS journalFebruary 1, 2023Doi K, Takeuchi H, Sakurai H.

(14) Therapeutic targeting of hepatocellular carcinoma cells with antrocinol, a novel, dual-specificity, small-molecule inhibitor of the KRAS and ERK oncogenic signaling pathwaysChemico-biological interactionsJanuary 25, 2023Hsu CH, Weng PW, Chen MY, Yeh CT, Setiawan SA, Yadav VK, Wu ATH, Tzeng DTW, Gong JX, Yang Z, et al.

(15) PFKFB4 facilitates palbociclib resistance in oestrogen receptor-positive breast cancer by enhancing stemnessCell proliferationJanuary 1, 2023Wang S, Bei Y, Tian Q, He J, Wang R, Wang Q, Sun L, Ke J, Xie C, Shen P.conjugated,Abclonal,AC028 Anti‐GAPDH‐HRP conjugated,KANG CHEN,KC‐5G5 OCT4,Bioss,bs‐0830R CDK4,Santa Cruz Biotechnology,sc‐56277 Phospho‐CDK4‐T172,Abclonal,AP0593 CCND1,Bioss,bs‐0623R RB1,Bioss,bs‐2777R Phospho‐ RB‐S780,Bioss,bs‐1347R PFKFB4,Zhengneng

(16) Immortalization of common marmoset-derived fibroblasts via expression of cell cycle regulators using the piggyBac transposonTissue & cellAugust 1, 2022Orimoto A, Shinohara H, Eitsuka T, Nakagawa K, Sasaki E, Kiyono T, Fukuda T.

(17) Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroupScientific reportsJuly 20, 2022Martinez-Monleon A, Kryh Öberg H, Gaarder J, Berbegall AP, Javanmardi N, Djos A, Ussowicz M, Taschner-Mandl S, Ambros IM, Øra I, et al.Supplementary Fig. 9. The blots were probed overnight at 4 °C with the following antibodies: CDK4 (sc-56277), CDK6 (sc-7961), MDM2 (sc-965), p53 (sc-126), PUMA (sc-374223), and RB (sc-102) from Santa Cruz Biotechnology

(18) Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-κB signaling pathway in osteoblastsBMC musculoskeletal disordersApril 11, 2022Guo Y, Fan J, Liu S, Hao D.

(19) Cx43 overexpression is involved in the hyper-proliferation effect of trichloroethylene on human embryonic stem cellsToxicologyJanuary 15, 2022Xia Y, Jiang B, Teng Z, Liu T, Wang J, Aniagu S, Zhang G, Chen T, Jiang Y.

(20) Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC CellsInternational journal of molecular sciencesJanuary 12, 2022Kolloch L, Kreinest T, Meisterernst M, Oeckinghaus A.(Cell Signaling Technology, 77055), pCDK4 Thr172 (Abclonal, Woburn, MA, USA; AP0593), CDK4 (Santa Cruz, sc-56277), CDK2 (Santa Cruz, sc-6248), GAPDH (Proteintech, Planegg, Germany, 60004), Actin (Santa Cruz, sc-1615),

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Cdk4 (DCS-31) Antibody

Cdk4 (DCS-31) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Cdk4 (DCS-31) Antibody from Santa Cruz Biotechnology, Inc.

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