Apaf-1 (5E11) Antibody sc-65891 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemApaf-1 (5E11) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-65891
Antibody TypePrimary Antibodies
Quantity50 µg/0.5 ml
Clone5E11
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, IHC(P)
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
NCBI Gene Aliases6230400I06Rik, APAF-1, Apaf-1, mKIAA0413, CED4, fog, Apaf1l
NCBI Full Gene Nameapoptotic peptidase activating factor 1
TargetApaf1
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) LncRNA EGFR-AS1 inhibits ferroptosis to reduce radiosensitivity of cervical cancer through the m6A/IGF2BP3/APAF1 axisBMC CancerMarch 5, 2026Xianglong Chen, Jingyu Li, Yujie Sun, Zhaoyu Ye, Man Long, Junguo Bu, Zirong Fan, Zhaojing Jiangagainst ACSL4 (ab155282, Abcam), and GPX4 (ab125066, Abcam) IGF2BP3 (14642-1-AP, Proteintech), and APAF1 (sc-65891, Santa Cruz) over night at 4 °C. Tissue sections were then washed with PBS and incubated with secondary

(2) Effects of Dexmedetomidine Treatment After Cerebral Ischemia/Reperfusion on Apoptosis and Oxidative Stress: A Rat ModelLife (Basel)February 13, 2026Mahir Kuyumcu, Eda Yıldızhanwas performed to evaluate apoptotic protein expression (Bax, Bcl-2, APAF-1, catalog numbers: sc-7480; sc-65891; sc-13561; Santa Cruz Biotechnology Inc., Heidelberg, Germany; dilution: 1/100, respectively). Paraffin-embedded

(3) Fulvic acid protected hepatic tissue from amoxicillin/clavulanate-induced hepatotoxicityJournal of Veterinary ScienceJanuary 1, 2026Hasan Mansur Durgun, Eda Yildizhansolution for 8 min. The samples were incubated with the primary antibody Bcl-2 and Bax (catalog No. sc-65891 and sc-7480, respectively, Santa Cruz Biotechnology, Germany, dilution ratio:1/100). The samples were

(4) Baicalin Improves Skeletal Muscle Atrophy by Attenuating DRP-1-Mediated Mitochondrial Fission in Aged MiceMusclesAugust 19, 2025Hla Myat Mo Mo, Jong Han Lee(sc-271583, Santa Cruz Biotechnology, Dallas, TX, USA); anti-apoptotic protease activating factor 1 (Apaf-1) (sc-65891, Santa Cruz Biotechnology, Dallas, TX, USA); anti-caspase 3 (14220S, Cell Signaling Tech, Danvers, MA,

(5) Zonisamide Ameliorated the Apoptosis and Inflammation in Cerebellar Tissue of Induced Alcohol Addiction Animal ModelLife (Basel)June 24, 2024Fırat Aşır, Fikri Erdemci, Zuhal Çankırı, Tuğcan Korak, Süreyya Özdemir Başaran, Özge Kaplan, Özkan Yükselmiş, Nilüfer Dönmezdil, Hayat Ayaz, Şehmus Kaplan, et al.sections were incubated overnight at a temperature of 4 °C with primary antibodies APAF-1 (catalog no: sc-65891, Santa Cruz Biotechnology, Inc. 10410 Finnell Street Dallas, TX 75220, USA, 1/100) and TNF-α (catalog

(6) Role of heat shock protein 70 in silibinin-induced apoptosis in bladder cancerJ CancerJanuary 1, 2024Yi Wei, Yanxin Zhuang, Yishuai Zhang, Lei Luo, Bixin Yu, Jin Zengmanufacturer's instructions. Briefly, protein G Dynabeads were coated with rabbit anti-Apaf-1 (cat. no. sc-65891; Santa Cruz Biotechnology, CA) under rotation for 1 hour at 4 °C. In order to eliminate antibody contamination

(7) 3-Deoxysappanchalcone Inhibits Cell Growth of Gefitinib-Resistant Lung Cancer Cells by Simultaneous Targeting of EGFR and MET KinasesBiomolecules & therapeuticsJuly 1, 2023Lee JY, Lee SO, Kwak AW, Chae SB, Cho SS, Yoon G, Kim KT, Choi YH, Lee MH, Joo SH, et al.

(8) Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male miceNature communicationsApril 1, 2023Zhao Q, Dai MY, Huang RY, Duan JY, Zhang T, Bao WM, Zhang JY, Gui SQ, Xia SM, Dai CT, et al.following antibodies were used in western blot, immunohistochemistry and immunofluorescence: Apaf-1 (sc-65891, Santa Cruz Biotechnology, USA; WB 1:200 dilution), Caspase-11 (ab180673, Abcam, UK; WB 1:1000 dilution),

(9) Evaluation of Effect of Honey Sugars Analogue Therapy against Breast Cancer Induced by 1-Methyl-1-nitrosourea in In Vivo Breast Cancer ModelJournal of oncologyJanuary 1, 2022Ahmed S, Nawaz S, Murtey MD, Ibrahim M, Ahmad W, Idrees MA, Che Jalil NA, Othman NH.immunohistochemically stained for the markers. Apaf-1 with mouse monoclonal anti-Rat Apaf-1 antigen (catalog no. SC-65891, Santa Cruz Biotechnology Inc., USA; diluted at 1 : 100), caspase-9 Rabbit polyclonal anti-rat caspase-9

(10) miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite MannerBiomedicinesDecember 25, 2021Marwarha G, Røsand Ø, Scrimgeour N, Slagsvold KH, Høydal MA.µg,Rabbit,Novus Biologicals,NBP1-77000,AB_11008194 APAF1,ELISAcapture,50 ng/well,Mouse,Santa Cruz Biotechnology,sc-65891,AB_1119006 APAF1,ELISAdetection,50 ng/well,Rabbit,Novus Biologicals,NBP1-77000,AB_11008194 c-FLIP,ELISAcapture,50

(11) Apaf-1 Pyroptosome Senses Mitochondrial Permeability TransitionCell metabolismFebruary 2, 2021Xu W, Che Y, Zhang Q, Huang H, Ding C, Wang Y, Wang G, Cao L, Hao H.

(12) Mitochondrial apoptosis and curtailment of hypoxia-inducible factor-1α/fatty acid synthase: A dual edge perspective of gamma linolenic acid in ER+ mammary gland cancerCell biochemistry and functionJuly 1, 2020Roy S, Singh M, Rawat A, Kumar D, Kaithwas G.

(13) PHD-2 activation: a novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtypeNaunyn-Schmiedeberg's archives of pharmacologyOctober 1, 2019Devi U, Singh M, Roy S, Tripathi AC, Gupta PS, Saraf SK, Ansari MN, Saeedan AS, Kaithwas G.

(14) Alpha-linolenic acid based nano-suspension protect against lipopolysaccharides induced mastitis by inhibiting NFκBp65, HIF-1α, and mitochondria-mediated apoptotic pathway in albino Wistar ratsToxicology and applied pharmacologyAugust 15, 2019Yadav RK, Tripathi CB, Saraf SA, Ansari MN, Saeedan AS, Aldosary S, Rajinikanth PS, Kaithwas G.

(15) Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory ImpairmentJournal of clinical medicineJune 14, 2019Ahmad A, Ali T, Rehman SU, Kim MO.

(16) Activation of prolyl hydroxylase-2 for stabilization of mitochondrial stress along with simultaneous downregulation of HIF-1α/FASN in ER + breast cancer subtypeCell biochemistry and functionJune 1, 2019Devi U, Singh M, Roy S, Gupta PS, Ansari MN, Saeedan AS, Kaithwas G.

(17) Transcutaneous Vagus Nerve Stimulation Regulates the Cholinergic Anti-inflammatory Pathway to Counteract 1, 2-Dimethylhydrazine Induced Colon Carcinogenesis in Albino wistar RatsFrontiers in pharmacologyJanuary 1, 2019Rawat JK, Roy S, Singh M, Guatam S, Yadav RK, Ansari MN, Aldossary SA, Saeedan AS, Kaithwas G.

(18) Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different MechanismsCell chemical biologyOctober 18, 2018Park SH, Baek KH, Shin I, Shin I.

(19) GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinomaThe international journal of biochemistry & cell biologyMarch 1, 2018Roy S, Singh M, Rawat A, Devi U, Gautam S, Yadav RK, Rawat JK, Ansari MN, Saeedan AS, Kumar D, et al.

(20) Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemopreventionOncotargetSeptember 19, 2017Roy S, Rawat AK, Sammi SR, Devi U, Singh M, Gautam S, Yadav RK, Rawat JK, Singh L, Ansari MN, et al.

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Apaf-1 (5E11) Antibody

Apaf-1 (5E11) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

Citations (26)

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Apaf-1 (5E11) Antibody from Santa Cruz Biotechnology, Inc.

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