Anti-MHC Class II antibody ab180779 from Abcam

Product Specs
ItemAnti-MHC Class II antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab180779
Quantity100 µL
ApplicationsIHC-P, WB
Conjugate/TagUnconjugated
Concentration1 mg/ml
ReactivityHuman
TargetHLA-DPB1
IsotypeIgG
HostRabbit
Gene NameHLA-DPB1
Antibody TypePrimary Antibody
NCBI Gene AliasesDPB1, HLA-DP, HLA-DP1B, HLA-DPB
ClonalityPolyclonal
Research AreaImmuno-oncology
NCBI Full Gene Namemajor histocompatibility complex, class II, DP beta 1

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Forced polarisation of microglia by IL-13 is modified by inflammatory and microenvironmental contextInflammation ResearchDecember 1, 2025Emmanuelle D. Aiyegbusi, James P. Reynolds, Ross O’Carroll, Ruth Colbert, Christopher Carew, Dearbhaile Dooleytemperature using protein block (Abcam, ab64226) After blocking, the primary antibodies, Anti-MHCII (Abcam, ab180779), Anti-Iba1 (FujiFilm Wako, 019–19741), Anti-Arginase 1 (Abcam, ab91279) and Anti-F4/80 (BioRad, MCA497GA)

(2) Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen‐Deficient Environments via the Amplifier Extracellular VesiclesAdvanced ScienceJuly 12, 2025Danfeng Li, Tian Yang, Yuqian Li, Xinwei Lyu, Cheng Hu, Jiayin Yan, Jiali TanUSA), anti‐Myeloperoxidase (MPO) antibody (ab9535, Abcam, USA) and rabbit‐anti‐mouse anti‐MHC antibody (ab180779, Abcam, USA). On the next day, they were washed with PBS three times and stained with goat‐anti‐rabbit

(3) Immune-featured stromal niches associate with response to neoadjuvant immunotherapy in oral squamous cell carcinomaCell Reports MedicineMarch 18, 2025Yu-Tong Liu, Hai-Ming Liu, Jian-Gang Ren, Wei Zhang, Xin-Xin Wang, Zi-Li Yu, Qiu-Yun Fu, Xue-Peng Xiong, Jun Jia, Bing Liu, et al.1:400), SELP (ab6632, Abcam, 1:200), ICAM1 (67836S, CST, 1:200), CD3 (85061S, CST, 1:400), MHC-II (ab180779, Abcam, 1:200), PDGFRα+β (ab32570, Abcam, 1:400), APOD (ab256496, Abcam, 1:400), CD56 (99746S, CST,

(4) Modulation of MHC expression by interferon-gamma and its influence on PBMC-mediated cytotoxicity in canine mast cell tumour cellsScientific reportsAugust 1, 2024Bhanpattanakul S, Tharasanit T, Buranapraditkun S, Sailasuta A, Nakagawa T, Kaewamatawong T.(mouse monoclonal, 1:200, DG-H58A, Novus Biologicals, USA) and anti-MHC II (rabbit polyclonal, 1:500, ab180779, Abcam, USA) at 4 °C overnight. Afterward, the cells were washed with PBS and incubated with the secondary

(5) Artificial Extracellular Vesicles Generated from T Cells Using Different Induction TechniquesBiomedicinesApril 20, 2024Ekaterina A. Zmievskaya, Sabir A. Mukhametshin, Irina A. Ganeeva, Elvina M. Gilyazova, Elvira T. Siraeva, Marianna P. Kutyreva, Artur A. Khannanov, Youyong Yuan, Emil R. Bulatovused: CD3 (ab699, Abcam, Waltham, MA, USA), granzyme B (ab134933, Abcam, Waltham, MA, USA), MHCII (ab180779, Abcam, Waltham, MA, USA), calnexin (MAA280Hu22, Cloud-Clone, Wuhan, China), HSP-70 (AF5466, Affinity,

(6) The application of HER2 and CD47 CAR-macrophage in ovarian cancerJournal of translational medicineSeptember 22, 2023Chen Y, Zhu X, Liu H, Wang C, Chen Y, Wang H, Fang Y, Wu X, Xu Y, Li C, et al.antibodies were included: anti-proliferating cell nuclear antigen (PCNA) (ab92552, Abcam), MHC II (ab180779, Abcam), CD163 (ab182422, Abcam), IFN-γ (ab218426, Abcam), HER2 (ab134182, Abcam), CD47 (ab218810, Abcam),

(7) Gene Immunotherapy of Colon Carcinoma with IL-2 and IL-12 Using Gene ElectrotransferInt J Mol SciAugust 17, 2023Tilen Komel, Masa Omerzel, Urska Kamensek, Katarina Znidar, Ursa Lampreht Tratar, Simona Kranjc Brezar, Klemen Dolinar, Sergej Pirkmajer, Gregor Sersa, Maja Cemazarwere used: 1/100 for rabbit anti-mouse F4/80 (ab111101), 1/200 for rabbit anti-mouse MHC class II (ab180779), 1/100 for rabbit anti-mouse CD4 (ab183685), 1/1000 for rabbit anti-mouse CD8 (ab209775), 1/200 for

(8) Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsisSignal transduction and targeted therapyJune 19, 2023Zhang SY, Xu QP, Shi LN, Li SW, Wang WH, Wang QQ, Lu LX, Xiao H, Wang JH, Li FY, et al.RAB5(AR038) from Beyotime. SHP1 (ab32559), SHP-2 (ab131541), phospho-SHP1 at Y536 (ab51171), anti-MHCII (ab180779), anti-MHCII (ab25681), anti-TLR4 (ab22048), anti-SHP2 (ab131541), anti-P-SHP2 (ab62322) mouse IgG isotype control

(9) miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosisThe Journal of biological chemistryJune 1, 2023Chen F, Ning Y, Liu J, Lian M, Wang J, Dan H.(mice),Rabbit,ab203128,Abcam,1:1000 Mac-1,Rabbit,ab185723,Abcam,1:1000 VLA4,Rabbit,ab81280,Abcam,1:1000 ZEB2,Rabbit,ab191364,Abcam,1:1000 MHC-II (human),Mouse,ab55152,Abcam,1:1000 MHC-II (mice),Rabbit,ab180779,Abcam,1:1000 IL-1β,Mouse,12242,CST,1:1000 CD206,Rabbit,ab64693,Abcam,1:1000 Bcl-2,Rabbit,ab59348,Abcam,1:1000 Bax,Rabbit,ab32503,Abcam,1:1000 C

(10) Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1Cell death & diseaseMay 30, 2023Yang R, Li L, Hou Y, Li Y, Zhang J, Yang N, Zhang Y, Ji W, Yu T, Lv L, et al.scanned with an Odyssey Imaging system (LI-COR, NE, USA). The primary antibodies used were anti-β-MHC (ab180779, Abcam, Cambridge, MA, USA), anti-YBX1 (20339-1-AP, Proteintech, Wuhan, China), and anti-GAPDH (10494-1-AP,

(11) Long noncoding RNA Mhrt alleviates angiotensin II-induced cardiac hypertrophy phenotypes by mediating the miR-765/Wnt family member 7B pathwayOpen Med (Wars)May 12, 2023Manli Yuan, Huaping Jia, Bei Zhao, Can Zhang, Xiaowen Zuoincubated with primary antibodies (anti-ANP: ab209232, 1:1,000; anti-BNP: ab236101, 1:2,000; anti-β-MHC: ab180779, 1:2,000; and anti-β-actin: ab8227, 1:5,000; Abcam, Cambridge, CA, USA) overnight at 4°C and then incubated

(12) Antigen-Loaded Extracellular Vesicles Induce Responsiveness to Anti–PD-1 and Anti–PD-L1 Treatment in a Checkpoint Refractory Melanoma ModelCancer Immunology ResearchFebruary 3, 2023Rosanne E. Veerman, Gözde Güclüler Gucluler Akpinar, Annemarijn Offens, Loïc Steiner, Pia Larssen, Andreas Lundqvist, Mikael C.I. Karlsson, Susanne Gabrielssonprimary antibodies anti-OVA (1: 4,000; clone 0220–1682G, AO Serotec/Bio-Rad), anti-MHCII (1: 4,000; clone ab180779, Abcam), anti-calnexin (1:1,000; ab10286, Abcam), and anti-actin (1:10,000; Sc1616, Santa Cruz), followed

(13) Antigen-Loaded Extracellular Vesicles Induce Responsiveness to Anti–PD-1 and Anti–PD-L1 Treatment in a Checkpoint Refractory Melanoma ModelCancer Immunol ResJanuary 10, 2023Rosanne E. Veerman, Gözde Güclüler Akpinar, Annemarijn Offens, Loïc Steiner, Pia Larssen, Andreas Lundqvist, Mikael C.I. Karlsson, Susanne Gabrielssonprimary antibodies anti-OVA (1: 4,000; clone 0220–1682G, AO Serotec/Bio-Rad), anti-MHCII (1: 4,000; clone ab180779, Abcam), anti-calnexin (1:1,000; ab10286, Abcam), and anti-actin (1:10,000; Sc1616, Santa Cruz), followed

(14) Highly reproducible rat arterial injury model of neointimal hyperplasiaPloS oneJanuary 1, 2023Tan RP, Hung JC, Chan AHP, Grant AJ, Moore MJ, Lam YT, Michael P, Wise SG.contractile and synthetic phenotype respectively, and CD68 (Abcam, ab92552, 1:500), MHC Class II (Abcam, ab180779, 1:500), IL-1β (ThermoFisher, P420B, 1:200), and TNF-α (Abcam, ab6671, 1:200) for vascular inflammation.

(15) CD4(+) CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured LiverAging and diseaseDecember 1, 2022Shen S, Li Y, Jin M, Fan D, Pan R, Lin A, Chen Y, Xiang L, Zhao RC, Shao J.used in western blot and flow cytometry are as follows: anti-MHC-II polyclonal antibody (Abcam, cat. no. ab180779), anti-GAPDH mAb (Invitrogen, cat. no. 398600), Goat anti-Rabbit IgG HRP polyclonal antibody (Abcam,

(16) Tumor Microenvironment and Immune Escape in the Time Course of GlioblastomaMolecular neurobiologyNovember 1, 2022Virtuoso A, De Luca C, Cirillo G, Riva M, Romano G, Bentivegna A, Lavitrano M, Papa M, Giovannoni R.Novus bio, NBP1-07,035, Milan, Italy); rabbit antibodies against MHC Class II (MHCII) (1:500, Abcam, ab180779, Cambridge, UK); rabbit antibodies to MMP9 (1:500, Invitrogen, JA80-73, Waltham, USA); rabbit antibodies

(17) Single-cell transcriptomics reveals functionally specialized vascular endothelium in braineLifeOctober 5, 2022Jeong HW, Diéguez-Hurtado R, Arf H, Song J, Park H, Kruse K, Sorokin L, Adams RH.(Abcam ab53444, 1:200), goat anti-Olig2 (R&D Systems AF2418, 1:100), rabbit anti-MHC Class II (Abcam ab180779, 1:100), rat anti-CD45 (Becton Dickinson 550539, 1:200), and rat anti MBP (Abcam ab7349, 1:200). The

(18) Protective effect of growth differentiation factor 15 in sepsis by regulating macrophage polarization and its mechanismBioengineeredApril 14, 2022Xinliang Zhang, Shimin DongCompany, USA); Ly6C antibody (ab24973; Abcam, UK); Ly6G antibody (ab25377; Abcam, UK); MHC-II antibody (ab180779; Abcam, UK); PI3K inhibitor, LY294002, and corresponding phosphorylated antibody (Cell Signaling Technology,

(19) ACE2 Is Expressed in Immune Cells That Infiltrate the Placenta in Infection-Associated Preterm BirthCellsJuly 8, 2021Lye P, Dunk CE, Zhang J, Wei Y, Nakpu J, Hamada H, Imperio GE, Bloise E, Matthews SG, Lye SJ.anti-rabbit ACE2 (1:200, ab15348, Abcam, Toronto, ON, Canada) rabbit anti-Human MHC-II (M1 marker) (1:400, ab180779, Abcam), anti-rabbit mannose receptor (M2 marker) (CD206, 1:200, ab64693, Abcam), anti-mouse CD68 (macrophage)

(20) Tim-3 Relieves Experimental Autoimmune Encephalomyelitis by Suppressing MHC-IIFrontiers in immunologyJanuary 1, 2021Tang L, Li G, Zheng Y, Hou C, Gao Y, Hao Y, Gao Z, Mo R, Li Y, Shen B, et al.primary antibodies overnight at 4°C: anti-CIITA antibody (Abcam, ab49132), anti-MHC-II antibody (Abcam, ab180779), and anti-mouse β-actin antibody (Abcam, ab8227). The dilution method of the above antibodies is according

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Anti-MHC Class II antibody from Abcam

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Anti-MHC Class II antibody from Abcam

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