Notch3 Antibody 2889S from Cell Signaling Technology

Product Specs
ItemNotch3 Antibody
CompanyCell Signaling Technology
Price $394.00 Inquire
Catalog Number2889S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetNotch3
HostRabbit
NCBI Gene AliasesCADASIL, CADASIL1, CASIL, IMF2, LMNS
NCBI Full Gene Namenotch receptor 3
ClonalityPolyclonal
Research AreaDevelopmental Biology
Molecular Weight90, 270

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) HCMV promotes viral reactivation through the coordinated regulation of Notch signaling by UL8 and miR-UL36mBioMarch 11, 2026Aaron Dirck, Nicole Diggins, Wilma Perez, Christopher Parkins, Michael Daily, Rebekah L. Turner, Luke Slind, Linh Nguyen, Daniel Malouli, Guanming Wu, et al.synthesized by Integrated DNA Technologies. The following commercial antibodies were used: Notch3 (2889, Cell Signaling), RBPJ (5442, Cell Signaling), GAPDH (ab8245, Abcam), HCMV IE2 (MAB810, Sigma Aldrich),

(2) NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomasJournal of neuro-oncologyDecember 1, 2025Sadagopan NS, Gomez M, Tripathi S, Billingham LK, DeLay SL, Cady MA, Congivaram HTS, Chia TY, Wan H, Wang S, et al.then incubated overnight at 4 °C with primary antibodies against NOTCH3 (Cell Signaling Technology, #2889, 1:500) and GAPDH (Cell Signaling Technology, #2118, 1:2000). After washing, the membrane was incubated

(3) A Patient-Derived Scaffold-Based 3D Culture Platform for Head and Neck Cancer: Preserving Tumor Heterogeneity for Personalized Drug TestingCellsOctober 2, 2025Alinda Anameriç, Emilia Reszczyńska, Tomasz Stankiewicz, Adrian Andrzejczak, Andrzej Stepulak, Matthias Nees(ab39973, Abcam), anti-Vimentin (sc-6260, Santa Cruz Biotechnology, Dallas, TX, USA), and anti-NOTCH3 (2889S, Cell Signaling Technology, Danvers, MA, USA). The secondary antibodies used were Horseradish peroxidase-conjugated

(4) Investigation of biomarkers and associated molecular mechanism shared between colorectal cancer and lung adenocarcinomaDiscov OncolAugust 12, 2025Kun Gao, Lianyang Yu, Lei Wang, Linlu Gao, Tingting Li, Jing SunCatalog Number: ab13492), anti-NOTCH3 antibody (1:1000, Cell Signaling Technology, Catalog Number: 2889 S), anti-SMAD9 antibody (1:1000, Thermo Fisher Scientific, Catalog Number: PA5-47403), anti-GPD1L antibody

(5) Highly quantitative measurement of differential protein-genome binding with PerCell chromatin sequencingCell Reports MethodsJune 16, 2025Alexi Tallan, Jack Kucinski, Benjamin Sunkel, Cenny Taslim, Stephanie LaHaye, Qi Liu, Jun Qi, Meng Wang, Genevieve C. Kendall, Benjamin Z. StantonRRID:AB_2106495 anti-H3K27ac Ab,Active Motif,Cat#39133; RRID:AB_2561016 anti-CTCF Ab,Cell Signaling Technologies,Cat#2889; RRID:AB_2086794 ,, "Chemicals, peptides, and recombinant proteins","Chemicals, peptides, and recombinant

(6) Induction of T-Cell Differentiation by KLF4 in T-Cell Acute Lymphoblastic Leukemia Cells Harboring Activating Mutation in NOTCH3FASEB JMay 31, 2025Mina Noura, Takahiko Yasuda, Hitoshi Kiyoi, Fumihiko HayakawaSanta Cruz Biotechnology, USA), anti‐KLF4 (#4038; Cell Signaling Technology, USA), and anti‐Notch3 (#2889; Cell Signaling Technology). Horseradish peroxidase (HRP)‐conjugated anti‐rabbit IgG and anti‐mouse

(7) Induction of T‐Cell Differentiation by KLF4 in T‐Cell Acute Lymphoblastic Leukemia Cells Harboring Activating Mutation in NOTCH3FASEB JMay 12, 2025Mina Noura, Takahiko Yasuda, Hitoshi Kiyoi, Fumihiko HayakawaSanta Cruz Biotechnology, USA), anti‐KLF4 (#4038; Cell Signaling Technology, USA), and anti‐Notch3 (#2889; Cell Signaling Technology). Horseradish peroxidase (HRP)‐conjugated anti‐rabbit IgG and anti‐mouse

(8) Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic CellsInternational Journal of Molecular SciencesJanuary 24, 2024Sandesh Kumar Patel, Nadezda Zhdanovskaya, Ilaria Sergio, Antonella Cardinale, Marco Rosichini, Claudia Varricchio, Eleonora Pace, Carlo Capalbo, Franco Locatelli, Alberto Macone, et al.and probed with the following antibodies: NOTCH1Val1744 (#4147), NOTCH3Intracellular (IC) domain (#2889), NOTCH1 IC domain (#3608) all purchased from Cell Signaling Technology, Danvers, MA, USA; and β-actin

(9) Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney diseasebioRxiv : the preprint server for biologySeptember 13, 2023Thornton M, Sommer N, McGonigle M, Ram AK, Yerrathota S, Ehirim H, Chaturvedi A, Phan JD, Chakravarthi PV, Gunewardena S, et al.A5441); anti-p-NF-κB and anti-Notch3 (1:1000; Cell Signaling Technology, Danvers, MA, USA; 3033s and 2889); anti-MMP-10 (1:1000; My Bio Source, San Diego, CA, USA; MBS2027749); anti-Notch3, DLL4, Jagged1 (1:1000;

(10) Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALLCancers (Basel)November 24, 2022Nadezda Zhdanovskaya, Sara Lazzari, Diego Caprioglio, Mariarosaria Firrincieli, Chiara Maioli, Eleonora Pace, Daniela Imperio, Claudio Talora, Diana Bellavia, Saula Checquolo, et al.Cell Signaling Technology, Danvers, MA, USA), Notch1 (D1E11) (3608; Cell Signaling Technology), Notch3 (2889; Cell Signaling Technology), PARP (9542; Cell Signaling Technology), p27 Kip1 (D37H1) (3688; Cell Signaling Technology

(11) GATA2-Mediated Transcriptional Activation of Notch3 Promotes Pancreatic Cancer Liver MetastasisMolecules and cellsMay 31, 2022Lin H, Hu P, Zhang H, Deng Y, Yang Z, Zhang L.from Fusheng Industrial Co., Ltd. (China). Antibodies against NICD1 (Cat No. 3608) and NICD3 (Cat No. 2889) were purchased from Cell Signaling Technology (USA). Antibodies against β-actin (Cat No. sc-47778)

(12) Complex Changes in the Efficiency of the Expression of Many Genes in Monogenic Diseases, Mucopolysaccharidoses, May Arise from Significant Disturbances in the Levels of Factors Involved in the Gene Expression Regulation ProcessesGenes (Basel)March 26, 2022Zuzanna Cyske, Lidia Gaffke, Karolina Pierzynowska, Grzegorz WęgrzynSRSF10 rabbit antibody (#42267S, Cell Signaling Technology, Danvers, MA, USA), NOTCH3 rabbit antibody (#2889S, Cell Signaling Technology). For detection, secondary antirabbit antibodies and an Anti-Rabbit Detection

(13) JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiencyThe Journal of clinical investigationMarch 1, 2022Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, et al.Primary antibodies used for Western blot analysis were rabbit anti-NOTCH3 (Cell Signaling Technology, 2889; 1:500), rabbit anti-NOTCH2 (Cell Signaling Technology, 5732; 1:500), rabbit anti-DNMT1 (Cell Signaling Technology

(14) NOTCH3 limits the epithelial–mesenchymal transition and predicts a favorable clinical outcome in esophageal cancerCancer MedicineJune 1, 2021Norihiro Matsuura et al.Inc.). Sheared chromatin (20 μg) was incubated for immunoprecipitation with an antibody against NOTCH3 (#2889, dilution 1:50, Cell Signaling Technology) or RBPJ (ab25949, dilution 1:100, Abcam), or negative control

(15) Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein responseOncogenesisOctober 18, 2020Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, et al.as previously described23,24. Antibodies: from Cell Signalling (Danvers, MA, USA), anti-Notch3 (Cat#2889); anti-Notch1 (Cat#3608); anti-GRP78/Bip (Cat#3177); anti-IRE1α (Cat#3294); anti-CHOP (Cat#2895); anti-PARP

(16) Thymosin‑β�4 induces angiogenesis in critical limb ischemia mice via regulating Notch/NF‑κB pathwayInternational Journal of Molecular MedicineAugust 11, 2020Shumin Lv, Hongwen Cai, Yifei Xu, Jin Dai, Xiqing Rong, Lanzhi Zhengab86299; Abcam), p65 (1:1,000; 64 kDa; cat. no. ab16502; Abcam), Notch3 (1:1,000; 270 kDa; cat. no. 2889; Cell Signaling Technology, Inc.) and GAPDH (1:1,000; 37 kDa; cat. no. 5174; Cell Signaling Technology,

(17) Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Is a Superior Diagnostic Tool for the Identification and Differentiation of Mycoplasmas Isolated from AnimalsJournal of Clinical MicrobiologySeptember 1, 2019Joachim Spergser, Claudia Hess, Igor Loncaric, Ana S. RamírezCapote 275CT, W13K1, CH571, 1368, GI7, 2911 383T, 347, 1654/13, 2445/6, 201584/10, 4194 M432/72T, 3358, 2889, 2736, 1028, 664 H/T1T, 743, J1, 3026, 48533B, T4C CST, 1950, 1846, 86, 908, 2176, 756 B1/T1T, 2634G,

(18) miR-107 inhibits CDK6 expression, differentiation, and lipid storage in human adipocytesMolecular and cellular endocrinologyJanuary 5, 2019Ahonen MA, Haridas PAN, Mysore R, Wabitsch M, Fischer-Posovszky P, Olkkonen VM.(Sigma A6354), anti-Glut4 (Cell Signaling Technology 2213), anti-Notch3 (Cell Signaling Technology 2889), antiCDK6 (Novus Biologicals NBP1-87262), anti-Hes1 (Santa Cruz 25392), anti-p-Rb (Cell Signaling Technology

(19) Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALLFrontiers in oncologyJanuary 1, 2019Tottone L, Zhdanovskaya N, Carmona Pestaña Á, Zampieri M, Simeoni F, Lazzari S, Ruocco V, Pelullo M, Caiafa P, Felli MP, et al.Cell Signaling Technology, Beverly, MA, USA), Notch1 D1E11 (3608; Cell Signaling Tecnology), Notch3 (2889; Cell Signaling Technology), H3K27me3 (9733; Cell Signaling Technology), H3K27ac (4353; Cell Signaling Technology

(20) Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagationOncogeneDecember 1, 2018Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese AF, Noce C, Ciuffetta A, Vacca A, Besharat ZM, Bellavia D, et al.Anti-Flag(F3165), anti-β-actin(A5441) (Sigma-Aldrich); anti-Phospho-β-arrestin1-Ser412(2416), anti-Notch3(2889) (Cell-Signaling); anti-β-arrestin-1(sc-9182), anti-Phospho-Erk(sc-7383), anti-Erk-1/2(sc-93/sc-154),

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10/7/2015Excellent Antibody for Immunodetection of NOTCH3 in Mammalian Cells Raj KumarMammalian cells were cultured up to 70 percent confluence, serum starved for 12h and treated with growth factor. Proteins were extracted in RIPA buffer and resolved in 8% SDA-PAGE. Resolved proteins ... Read Review

Notch3 Antibody

Notch3 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Notch3 Antibody from Cell Signaling Technology

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