The Tetanus Toxin heavy chain Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to tetX. This antibody recognizes Bacteria/Archaea antigen. The Tetanus Toxin heavy chain Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-:-Phe-77' bond of synaptobrevin-2