Bioss Inc.'s LTBP1 Polyclonal Antibody, HRP Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA. The LTBP1 Polyclonal Antibody, HRP Conjugated was generated using LTBP1 as the antigen and it reacts with Homo Sapiens, and Human.
Description
Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1), a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex. LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures. Cleavage of LTBP results in LTBP-1, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation. LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas