The alpha 2C Adrenergic Receptor Antibody from Bioss Inc. is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The alpha 2C Adrenergic Receptor Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
alpha2C-adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson?s disease, panic disorders, and Huntington disease (HD) progression. A genetic variant in the alpha2C-AR coding region (Del322-325) renders the receptor partially uncoupled from Gi, and is a contributing risk factor for heart failure. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney